Chapter 17 - Special Senses Flashcards
Olfaction
The sense of smell
Olfactory Epithelium
Epithelial cells found in the roof of the nasal cavity
3 Cell Types Found in Olfactory Epithelium
- Supporting (Sustentacular) Cells
- Basal (Stem) Cells
- Olfactory Receptors
Supporting (Sustantecular) Cells
Provide support, insulation, nourishment, and detoxification to the olfactory epithelium
Basal (Stem) Cells
Layer that constantly divides to form new olfactory/gustatory receptors
Olfactory Receptors
- Pseudostratified bipolar sensory neurons sensitive to odorants
- Have 1 olfactory hair + 1 unmyelinated axon
- Bowman’s Glands = secrete mucous
Olfactory Transduction (6 Steps)
- Odorant binds to receptors on olfactory hairs
- G-protein linked activation of adenyl cyclase
- cAMP activation
- Na+ influx
- Generator potential
- Action potential
Olfactory Pathway
Olfactory receptors -> RIght & left olfactory nerves (penetrates cribiform plate) -> Olfactory bulbs (synapses w/ 2nd order relay neurons) -> Olfactory tracts -> Primary olfactory area
- Projections to limbic system & hypothalamus = visceral/emotional responses to smell & memory evoked responses
- Projection to thalamus = odor identification & discrimination area of frontal lobe
Primary Odors
- Hundreds in total
- Nose can recognize approx. 10,000 different odor combinations
- 10 to 100 million olfactory receptors present in epithelium
Odor Thresholds & Adaptation
- Smell threshold may be very low
- Adaptation to odors occurs quickly
- With age, decreased olfactory receptor no. = hyposmia/ anosmia
Gustation
The sense of taste
5 Primary Taste Sensations
- Bitter
- Sour
- Salty
- Sweet
- Savory (Umami)
* Complex flavors = combinations of primary tastes + smell + tactile sensations
* Lowest sensitivity threshold = bitter
* Highest sensitivity threshold = savory
Adaptation
Decreased sensitivity due to constant stimulation
Tastants
Chemical substances that cause gustatory (taste bud) stimulation, as well as olfactory stimulation
Odorants
Chemical substances that cause olfactory stimulation, also affects gustation
3 Types of Epithelial Cells in Taste Buds
- Basal (Stem) Cells
- Supporting Cells
- Gustatory Receptors
Supporting Cells (Gustatory)
Provide nutritional support to other cells in taste buds
Gustatory Receptors
Have 1 gustatory hair (microvillus) which project from the taste pore which synapses w/ the 1st order sensory neuron
Taste Transduction (Ionic Tastes)
Dissolved tastants bind gustatory hairs -> Salty (Na+) and Sour (H+) enter cell via ion channels of different gustatory receptors -> Ca+2 influx -> Exocytotic release of neurotransmitter -> EPSPs in 1st order sensory neuron -> Firing of action potentials
Taste Transduction (Organic Tastes)
Dissolved tastants bind gustatory hairs -> Sweet, bitter, umami bind surface protein receptors of different gustatory receptors -> 2nd messenger release -> Closing of K+ channels, depolarizing cell -> Ca+2 influx + release of stored ER Ca+2 -> Increased cytosolic Ca+2 -> Exocytotic release of neurotransmitter -> EPSPS -> Action potential
4 Different Locations of Taste Buds
- Tongue
- Soft Palate
- Pharynx
- Epiglottis
* More taste buds associated w/ lingual papillae, located on dorsal/lateral tongue surface
4 Papillae Types
- Vallate Papillae
- Fungiform Papillae
- Foliate Papillae
- Filiform Papillae
Vallate Papillae
V-shaped row near back of tongue
Fungiform Papillae
Scattered over dorsal tongue surface
Foliate Papillae
Located on sides of tongue
Filiform Papillae
Most numerous on tongue; no taste buds, contain tactile receptors
Gustatory Pathway
Cranial nerves 7, 9, & 10 carry taste info -> Gustatory nucleus in medulla (synapse w/ 2nd order relay neurons) -> Limbic system & hypothalamus (emotional response) + Thalamus -> Primary gustatory area of parietal lobe & nearby association areas
3 Different Accessory Structures of the Eye
- Extrinsic Muscles
- Eyelids + Eyelashes
- Lacrimal Apparatus
3 Pairs of Extrinsic Eye Muscles
- Superior + Inferior Rectus: Elevation + Depression of eyeball
- Lateral + Medial Rectus: Abduction + Adduction of eyeball
- Superior + Inferior Oblique: Intorsion + Extorsion of eyeball
3 Cranial Nerves that Control Extrinsic Eye Muscles
- Oculomotor (3) nerve
- Trochlear (4) nerve
- Abducens (6) nerve
* Brainstem & cerebellum control eyeball movements
Functions of the eyelids
To provide shade, protection & lubrication to the eyball
Surface Anatomy of Eyelid (3 Parts)
- Palpebral Fissure = Space between upper & lower eyelids
- Lateral & Medial Commisures = Corners where the upper & lower eyelids meet
- Lacrimal Caruncle = Small, pink, globular nodule at the corner of the eyeball
Palpebral Layers of the Eyelid
- Epidermis
- Dermis
- SubQ tissue
- Orbicularis oculi
- Tarsal plate
- Tarsal gland
- Tarsal plate
- Areolar CT
- Palpebral conjunctiva
2 Eyelid Muscles
- Orbiculars Oculi = Closes eyelids
2. Levator Palpebrae Superioris = Opens eyelids
Tarsal Glands
- Embedded in tarsal plate
- Responsible for lipid-rich secretions
Chalazion
Cyst in the eyelid due to a blocked oil gland
2 Types of Conjuctiva
- Palpebral = Continuous w/ Bulbar Conjunctiva
- Bulbar Conjunctiva = Covers sclera, but not cornea
* Blood shot eyes caused by vasodilation due to irritation of bulbar conjunctiva
Eyelashes
- Blink reflex allows eyelashes to brush off dirt
- Sebaceous ciliary glands secrete oil which lubricates the eyes
- Sty = infection of sebaceous ciliary glands
2 Parts of the Lacrimal Apparatus
- Lacrimal Gland + Excretory Lacrimal Ducts
2. Lacrimal Sac + Superior & Inferior Lacrimal Canaliculi + Nasolacrimal Duct
Lacrimal Gland
- Secretes fluid (tears), contains salt, mucus & lysozyme
- Functions to protecct, clean & lubricate the eyes
- Parasympathetic innervation via Facial (7) nerve
- Tears -> Lacrimal puncta -> Superior & inferior lacrimal canaliculi -> Lacrimal Sac -> Nasolacrimal duct -> Nose
Dacrocystitis
Infection of the lacrimal sac; usually bacterial
3 Coats (Tunics) of the Eyeball
- Fibrous Tunic
- Vascular Tunic
- Retina
Fibrous Tunic (2 Main Parts)
- Sclera
2. Cornea
Sclera
White, dense CT, surrounds eyeball except at cornea
Cornea
Transparent cover over iris
Canal of Schlemm (AKA “Scleral Venous SInus”)
Drains aqueous humor
Vascular Tunic/Uvea (3 Main Parts)
- Choroid
- Ciliary Body
- Iris
Choroid
- Middle, dark brown layer of vascular tunic
- Has many blood vessels
- Absorbs stray light
Ciliary Body
- Runs from ora serrata to corneal/scleral junction
- Contains ciliary muscle (controls shape of lens)
- Ciliary process -> Aqueous humor & attach zonular fibers
- Accommodation for near vision = contraction of ciliary muscle; leads to decreased tension on zonular fibers, which leads to rounding up of lens
Iris
- Circular pigmented diaphragm, which regulates size of pupil
- Eye color = type & amount of melanin
- Eumelanin = black-brown pigment
- Pheomelanin = reddish-yellow pigment
2 Pupillary Responses to Light Intensity
- Miosis
2. Mydriasis
Miosis
Contraction of sphincter pupillae due to bright light (Parasympathetic)
Mydriasis
Contraction of dilator pupillae due to dim light (Sympathetic)
Retina/Inner Tunic (2 Layers)
- Pigmented Layer
2. Neural Layer