chapter 17- analgesia

Question 1

what can the metabolite of meperidine cause

Answer 1

seizures and CNS excitability

Question 2

what are some adverse effects seem with tramadol

Answer 2

MI, pancreatitis, anaphylaxis, seizure

Question 3

what is the sole anesthetic agent for procedures that do not require skeletal muscle relaxation

Answer 3

ketamine

Question 4

what is the clinical use for morphine

Answer 4

pain (moderate to severe); analgesia for mechanically ventilated patient

Question 5

what are some contraindications for codeine use

Answer 5

during delivery of premature infant; premature infant

Question 6

what can be used for acute opioid toxicity

Answer 6

naloxone

Question 7

what metabolizes morphine

Answer 7

liver

Question 8

what is an absolute contraindication for dextromethorphan use and why

Answer 8

cadmic of MAOI because of risk of serotonin syndrome

Question 9

what are some additional side effects seen with meperidine

Answer 9

euphoria and mydriasis

Question 10

what drug used in combination with naloxone results in greater anxiety tremors, palpitations, hot and cold flashes, and elevated plasma cortisol levels

Answer 10

yohimbine

Question 11

what medication is likely used for long-lasting pain relief in cancer patients

Answer 11

methadone

Question 12

what are some contraindications for naltrexone use

Answer 12

acute hepatitis or liver failure

Question 13

what opioid receptor antagonist can adversely cause pulmonary embolisms

Answer 13

naltrexone

Question 14

what is a contraindication for tramadol use

Answer 14

respiratory depression

Question 15

what is a contraindication for meperidine use

Answer 15

recent or concomitant MAOI use

Question 16

what forms are levorphanol available in

Answer 16

IV and oral forms

Question 17

how desk quinidine reduce analgesic effects of codeine

Answer 17

by inhibiting bioactivation of codeine to morphine

Question 18

what can be used for detoxification of patients with opioid addiction

Answer 18

methadone

Question 19

what does propoxyphene markedly increase the serum levels of a

Answer 19

carbamazepine

Question 20

what can be used for opioid, alcohol addiction

Answer 20

naltrexone

Question 21

what is the clinical application of dextromethorphan

Answer 21

cough, neuropathic pain

Question 22

why is a wider application of ketamine limited

Answer 22

its psychomimetic effects

Question 23

what is the clinical use of codeine

Answer 23

pain (mild to moderate); antitussive

Question 24

what are some adverse effects seen with dextromethorphan

Answer 24

dizziness, somnolence, fatigue

Question 25

what are some contraindications of morphine use

Answer 25

severe asthma, paralytic ileus, upper airway obstruction

Question 26

what are the clinical uses for alvimopan and methylnaltrexone use

Answer 26

postoperative ileus, opioid-mediated bowel dysfunction

Question 27

what are some adverse effects seen with methadone (in addition to those seen with morphine)

Answer 27

delayed respiratory depression, prolonged QT interval, torsades de pointes

Question 28

what adverse effect can be caused when codeine is given in excessive dose

Answer 28

codeine

Question 29

what type of pain is oxycodone and hydrocodone used for

Answer 29

moderate to severe

Question 30

what are some adverse effects seen with morphine use

Answer 30

respiratory depression, hypotension, confusion, abuse potential, constipation, urinary retention