Chapter 15 Review Flashcards
Glycolysis is the ______ enzymatic _______ of the glucose into _________.
10 step ; breakdown; 2 molecules of pyruvate
Pyruvate can
1) be further oxidized to produce energy
2) used as a precursor in biosynthesis
Glycolysis is a(n) ______ process driven by a large net __________ free energy.
irreversible ; decrease in
The overall glycolysis reaction:
Glucose+___ADP+___NAD+ +___Pi —>
_____Pyruvate+_____ATP+____NADH+____H+ +____H2O
2 ADP, 2 NAD+ , 2 Pi –> 2 Pyruvate, 2 ATP, 2 NADH, 2 H+, 2 H2O
Glycolysis has a net energy of
-85 kJ/mol
The phosphorylation of the glycolysis intermediates has 3 major functions:
1) Stops transportation of intermediates across the cell membrane
2) Activates the intermediates (high-energy metabolites)
3) Plays a role in substrate binding specificity for the enzymes in the glycolytic pathway
Hexokinase phosphorylates glucose at
C6
Hexokinase can phosphorylate :
phosphorylates D-glucose, D-mannose, D-fructose
Mg2+-ATP is a _________.
coenzyme (specifically, a cosubstrate)
Endergonic reactions are coupled to
ATP Hydrolysis
For every 1 glucose in glycolysis, you get
2 NADH and 4 ATP
Stage 1 of glycolysis
2 ATP are used
Stage 2 of glycolysis
4 ATPs are produced
Binding of glucose to ____________ induces a large conformational change.
hexokinase
___________ catalyzes ring opening followed by isomerization to convert G6P to fructose-6-P.
Phosphoglucose isomerase
