Chapter 15: Immune response and defence against disease Flashcards

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1
Q

What is antigen?

A

A substance which triggers and immune response

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2
Q

What are patter recognition receptors?

A

A cell receptor which recognises molecules associated with pathogens

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3
Q

What are pathogen associated molecular patterns?

A

A boarder molecule pattern associated with a pathogen

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4
Q

What is an innate immune response?

A

a non-specific response to pathogens that hasn’t been learnt

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5
Q

What is adaptive immune response?

A

A learnt response to a pathogen the body has faced before

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6
Q

What are the defence strategies in plants?

A

Physical barriers and chemical defence strategies

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7
Q

What are physical barrier in plants?

A

Thick outer bark, roots containing high amounts of waxy, water resistant materials

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8
Q

What are the chemical barriers in plants?

A

Some release toxins

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9
Q

What acts as the first line of defence against pathogens in human?

A

Skin

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10
Q

How is skin a physical barrier?

A

Skin is made up of epithelial cells which protects it from pathogens

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11
Q

What happens if the skin is broken?

A

Platelets are attracted to the site to clot the blood, they create a web like structure made of fibrin protein and forms a scab

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12
Q

How is skin a chemical barrier?

A

Glands in the skin produce oils and sweat which protect it from chemicals

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13
Q

How are we protected in openings?

A

The openings are lined with mucous membranes which produce mucous which traps pathogens

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14
Q

How does cilia help with pathogens?

A

Cilia pushes the mucous up the tract so it can be coughed or sneezed out

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15
Q

Can you pass micro-organisms out through urine?

A

Yes

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16
Q

What are macrophages?

A

Large white blood cells

17
Q

What is cytokines?

A

A small signalling molecule which coordinates inflammation and other immune response

18
Q

What is a mast cell?

A

A cell located in the tissue and released histamine and prostaglandins

19
Q

What is histamine?

A

A chemical that increases blood flow

20
Q

What is prostaglandin?

A

A group of lipids that cause vasodilatation, fever and pain

21
Q

What is vasodilatation?

A

The widening of arterioles

22
Q

What is the complement system?

A

A number of proteins that promote chemotaxis, cell lysis and phagocytosis.

23
Q

What is chemotaxis?

A

The movement of cell along the chemical gradient either away or toward the chemical stimulus

24
Q

What is phagocytosis?

A

The eating of invaders by phagocytes

25
Q

What is opsonisation?

A

A process wen a pathogen is covered in antibodies for ingestion and destruction

26
Q

What lymphocyte?

A

A type o leukocyte involves in adaptive immune repsonse

27
Q

What do b lymphocytes do?

A

Produce antibodies

28
Q

What do antibodies do?

A

They are shaped like a Y and bind cells to specific antigens

29
Q

What are the 2 types of B cells?

A

Plasma cells and memory cells

30
Q

What is the function of plasma cells?

A

They are highly specialised for producing antibodies

31
Q

What is the function of memory cells?

A

They store the information to produce antibodies

32
Q

How can antibodies destroy pathogens once attached?

A

Attracted phagocytes, act as toxins and link together to stop the movement

33
Q

What is cytotoxic T lymphocytes?

A

destroys virally infected or cancerous celled by secreting proteins (cytotoxins), originate in bone marrow

34
Q

What is immunodeficiency?

A

The suppression of the immune system, not able to fight off pathogens

35
Q

What is active immunity?

A

The immunity formed when the immune system is stimulated by memory cells

36
Q

What is passive immunity?

A

Immunity transferred from one person to another, no memory cells

37
Q

What are the two types of passive immunity?

A

Placenta and antibody serum injection