chapter 13: memory and learning Flashcards
The most striking impairment suffered by Henry Molaison (patient H.M.) was
anterograde amnesia
Nondeclarative memory is said to deal with _______ questions.
“how” questions
Knowing the meaning of word, without knowing where or when you learned it, describes _______ memory.
semantic memory
Patients with Korsakoff’s syndrome may _______ in an attempt to conceal gaps in their memory.
confabulate
The three successive systems that are necessary for recall of a past event are encoding, ________, and retrieval.
consolidation
Place cells, which are located in the _______, become active when an animal moves through its spatial environment or toward a particular location.
hippocampus
After a tetanus there are _______ AMPA receptors, and these receptors are _______ effective, so the synaptic response to glutamate is _______.
more; more; strengthened
NMDA receptors are gated by…
the ligand glutamate and a strong depolarization of the membrane
After a brief tetanus, the excitatory postsynaptic potential (EPSP) response increases significantly and remains high. This greater responsiveness is called
long-term potentiation (LTP).
learning
process of acquiring new information
memory
the ability to store and retrieve that information
amnesia
severe impairment of memory, usually as a result of accident or disease
retrograde amnesia
loss of memories prior to an event (such as surgery or trauma)
Patient H.M. (henry molaison)
unable to encode new declarative memories because of surgical removal of medial temporal lobe structures
anterograde amnesia
inability to form new memories after an event
hippocampus
a medial temporal lobe structure that is important for spatial cognition, learning, and memory
declarative memory
facts and information acquired through learning (“what” questions)
nondeclarative memory
procedural memory; memory about perceptual or motor procedures showed by performance (“how” questions)
delayed non-matching-to-sample-task
a test in which the individual must respond to the unfamiliar stimulus in a pair of stimuli
Patient N.A.
unable to encode new declarative memories, because of damage to the dorsomedial thalamus and the mammillary bodies