Chapter 13 Flashcards
the brain!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
four main regions of the brain
cerebrum, diencephalon, brainstem, cerebellum
gyri
ridges
sulci
depressions between ridges
fissures
deep sulci
gray matter
neuron cell bodies, dendrites, unmyelinated axons
cortex
superficial to gray matter
nucleus in gray matter
the region of gray matter; cluster of cell bodies
white matter
myelinated axons
tracts
bundles of myelinated axons
neurulation
formation of nervous tissue
when does neurulation begin?
3rd week of embryonic development
neural tube in the embryo
develops into CNS
step 1/3 of neurulation
neural plate formation - cells at the neural plate margin will become neural folds
step 2/3 of neurulation
tips of folds become neural crest cells; groove deepens, folds rise and “pinch” together
step 3/3 of neurulation
neural crest cells separate from neural folds and form other structures
neural tube formation
folds meet to form neural tube
neural tube surrounds:
neural canal
neuropores
openings at the end of neural tubes
when do neuropores close?
4th week of embryonic development
three primary vesicles
forebrain, midbrain, hindbrain
prosencephalon
forebrain
mesencephalon
midbrain
rhombencephalon
hindbrain
when do primary vesicles form?
late 4th week from the neural tube
secondary vesicles (8)
cerebrum
thalamus
hypothalamus
epithalamus
midbrain
pons
cerebellum
medulla oblongata
telencephalon
becomes cerebrum
diencephalon
becomes thalamus, hypothalamus, epithalamus
mesencephalon (2ndary vesicle)
becomes midbrain
metencephalon
becomes pons and cerebellum
mylencephalon
becomes medulla oblongata
anencephaly
substantial/complete absence of the brain
spina bifida
failure to close caudal part of neural tube
cystica
no formation of vertebral arch, have large cyst instea
occults
partial defect of bony arch
brain development @ 13-26 weeks
telencephalon envelops diencephalon; develops surface folds
brain development @ birth
brain fits in cranial cavity; most gyri and sulci are present
ventricles
cavities in brain
cerebrospinal fluid
contained within ventricles (CSF) and subarachnoid space; clear/colorless
ventricles are lined with:
ependymal cells
four ventricles in the brain
2 lateral ventricles in cerebrum (separated by septum pellucidum)
3rd ventricle in diencephalon (connects to lateral ventricles by interventricular septum
4th ventricle between pons and cerebellum (connects to 3rd ventricle by cerebral aqueduct)
septum pellucidum
partition between 2 lateral ventricles in cerebrum
interventricular septum
connects 3rd ventricle to lateral ventricles
cerebral aqueduct
connects 4th ventricle to 3rd ventricle
cerebral aqueduct
connects 4th ventricle to 3rd ventricle
which ventricle merges with the central canal of the spinal cord?
4th ventricle
functions of CSF
buoyancy (reduces brain weight)
protection (liquid cushion)
environmental stability (nutrient/waste transport)
CSF is formed by:
choroid plexus within ventricles
CSF drained through:
dural venous sinuses
blood-brain barrier
regulates what enters interstitial fluid of the brain
less blood-brain barrier in what regions?
choroid plexus, hypothalamus and pineal gland
cerebrum
origin of all complex intellectual functions
functions of cerebrum
intelligence/reasoning
thought/judgment
voluntary control (skeletal muscle)
conscience/senses
longitudinal fissure
separates left/right hemispheres
corpus callosum
connects hemispheres
hemispheres of brain
left controls right side of body, right controls left
5 lobes of cerebrum
frontal, parietal, temporal, occipital, insula
frontal lobe
biggest lobe of the brain; anterior to central sulcus
pre central gyrus
primary motor cortex of frontal lobe; voluntary movement
functions of cerebrum
motor control of muscles (on opposite side)
concentration
verbal communication
decision making
planning
personality
prefrontal cortex
responsible complex thought, judgment, personality, planning, deciding (not fully developed in adolescents)
Broca’s area
movements for vocalization (left side only)
parietal lobe
posterior to central sulcus
post central gyrus
primary somatosensory cortex; for sensory perception
functions of parietal lobe
general sense; proprioception, touch, pressure, pain, temp reception
(has association areas for identifying the feeling of objects)
temporal lobe
responsible for hearing and smell
primary auditory cortex
receives/processes/stores auditory info in temporal lobe
auditory association area
integrates/interprets sounds in temporal lobe
primary olfactory cortex
receives/processes/stores odor info
Wernicke’s area
language comprehension (left sided only) in temporal lobe
occipital lobe
backside of brain above cerebellum; vision and visual memories
primary visual cortex
received/processes/stores visual info
visual association areas
recognition
insula
deep to lateral sulcus, cannot be seen on surface (under temporal lobe); taste and memory
primary gustatory cortex
taste info in insula
cerebral white matter
myelinated axons grouped into tracts; deep to the cortex
association tracts
connect regions of the cortex within the same hemisphere
arcuate fibers
connect close regions within association tracts
longitudinal fasciculi
connect different lobes
commissural tracts
connect regions in different hemispheres
projection tracts
link cortex to the rest of the brain
internal capsule
between thalamus and cerebrum
cerebral lateralization
the brain is anatomically asymmetrical
left hemisphere
categorical; language/analysis
right hemisphere
representational; imagination/creatiivity, sense comparison
cerebral nuclei
helps regulate motor output
caudate nucleus
controls gait pattern of walking
lentiform nucleus
putamen - subconscious movement
globes pallidus - muscle tone
consciousness
amygdala
mood/emotions
3 parts of diencephalon (thalamus: keyword)
epithalamus, thalamus, hypothalamus
pineal gland
in epithalamus; endocrine gland that secretes melatonin
habenular nuclei
visceral/emotional responses to odors
thalamus
“sorting factory”; receives signals from all conscious senses except sense of smell; relays/filters signals and sends to proper cortex regions
hypothalamus
controls the autonomic nervous and endocrine system, body temp, hunger/thirst, emotional responses (part of limbic system)
pituitary gland
connects hypothalamus with infundibulum
autonomic nervous system
heart rate, blood pressure, digestion, respiration; controlled by hypothalamus
hypothalamus to pineal gland
directs it to secrete melatonin
limbic system
controls emotional responses (hypothalamus); pleasure and fear
brain stem
connects cerebrum, diencephalon, and cerebellum to spinal cord
ascending tracts
going up cerebrum; afferent/sensory info
descending tracts
going down periphery; efferent/motor
three parts of brain stem
midbrain, pons, medulla oblongata
midbrain
superior part of brain stem inferior to thalamus
substantial nigra
cluster of cells that appear black due to melanin; houses dopamine-producing neurons
texting
corpora quadrigemina; superior and inferior colliculi
superior colliculi
visual reflexes; tracking
inferior colliculi
auditory reflexes
pons
middle part of brain stem anterior to cerebellum
pontine respiratory center
controls skeletal muscles of breathing (inner costal muscles, diaphragm)
superior olivary nuclei
localizing sound
medulla oblongata
inferior part of brain stem; connects to spinal cord
pyramids
in medulla oblongata motor control
olives
in medulla oblongata; proprioception relays from cerebellum
cardiovascular center
cardiac and vasomotor center
cardiac center
regulates heart output
vasomotor center
regulates blood vessel diameter
medullary respiratory center
controls breathing rate
cerebellum
left/right hemisphere
three regions of cerebellum
cortex, arbor vitae, deep nuclei
cortex (cerebellum)
outer gray matter
arbor vitae
internal white matter
deep nuclei
gray matter
cerebellar penducles connect cerebellum to brain stem
connect cerebellum to brain stem
cerebellum functions
fine-tunes movement
ensures proper muscle activity patterns
muscle memory
equilibrium/posture
adjust motions to smoothness
motor plans/sensory feedback
vermis
connects two hemispheres of cerebellum
limbic system
emotional brain; processes/experiences emotions
hippocampus
forms long term memories (limbic)
amygdala
(limbic) emotion and memory; especially fear
olfactory components of limbic system
odors can produce emotions
reticular formation
loosely organized gray matter of brain stem; regulates muscle tone
reticular activating system
processes sensory info, sends signals to cortex about alertness
sleep
natural, temporary absences of consciousness; vital brain stems maintained
REM
rapid eye movement
non-REM sleep
growth, rest, energy conservation, strength renewal (75%)
REM sleep
eyes move; brain is active - memorable dreaming, consolidating memories (25%)
cognition
mental processes of awareness, knowledge, memory, perception, thinking
frontal lobe abnormality
personality, planning, decision making is altered
primary somatosensory cortex damage
loss of sensation awareness on opposite side of body
agnosia
cannot recognize stimuli meaning; sensation lost depends on lesion location
sensory memory
associations based on sensory input; few seconds
short term memory
limited capacity; bits of info; seconds to hours
long term memory
encoded from short term memory through repetition; lasts indefinitely, but can be lost if not occasionally retrieved
Wernicke’s area vs Broca’s area
Wernicke’s - language interpretation
Broca’s - language initiation
primary motor cortex
signals motor neurons to produce speech
protection of the brain
bones of skull, meninges, CSF, blood-brain barrier
three consecutive tissue layers of meninges
pia mater (deep), arachnoid mater, dura mater (superficial)
pia mater
innermost layer; directly on brain surface - thin areolar CT
arachnoid mater
middle layer; web of collagen/elastic fibers
(think spider webs! arachnid = spider)
subarachnoid space
deep to arachnoid mater, contains cerebrospinal fluid
subdural space
superficial to arachnoid mater, potential space
dura mater
thick, outer membrane; dense irregular CT
epidural space
superficial to dura mater, potential space
dural septa
dura mater sheets extend into cranial cavity; form partitions
falx cerebri
midline in cerebrum within longitudinal fissure; contains superior/inferior sagittal sinuses
tentorium cerebelli
tent over cerebellum; contains transverse and straight sinus
falx cerebelli
midline in cerebellum; contains occipital sinus
diaphragma sellae
small roof over sella turcica