Chapter 13 Flashcards

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1
Q

endocrine system

A

collection of specialized cells, tissues, and glands that produce and secrete circulating chemical messenger molecules called hormones

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2
Q

endocrine glands

A

ductless organs that secrete their products into interstitial fluid, lymph, and blood. secrete hormones

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3
Q

exocrine glands

A

secrete products such as mucus, sweat, tears, and digestive fluids into ducts that empty into the approprate sites.

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4
Q

hormones

A

bloodborne units of information, just as nerve impulses are units of information carried in nerves. some participate in feedback control loops regulating various body functions

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5
Q

How endocrine system communicates

A
  1. Hormones of the endocrine system reach nearly every living cell. this gives it advantage over nervous system cause it is in the blood and every cell has it
  2. Each hormone acts only on certain cells.
  3. Endocrine control tends to be slower than nervous system control
  4. The endocrine and nervous systems can (and often do) interact with each other.
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6
Q

target cells

A

hormone acts only on a certain group of cells called target cells because only the hormone’s target cells have the appropriate receptor to fit it

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7
Q

Steroid hormones

A

are structurally related to cholesterol and all are lipid soluble. enter the cell, bind to an intracellular receptor, and activate genes that produce new proteins

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8
Q

Nonsteroid hormones

A

structurally related to proteins, are lipid insoluble. bind to receptors on the cell’s surface, initiating a series of events that ultimately alters cellular activity in some way, even though the hormone never entered the cell at all

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9
Q

second messanger

A

carries the message provided by the hormone (the “first messenger”) without the hormone ever entering the cell. common 2nd messagner is cyclic AMP

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10
Q

hypothalamus

A

small region in the brain that serves as a homeostatic control center. produces 2 hormones of its own and it monitors and controls the hormone secretions of the pituitary gland, located directly beneath it and connected to it by a thin stalk of tissue

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11
Q

pituitary gland

A

called “master gland” because it secretes 8 different hormones that in turn regulate many of the other endocrine glands. consists of 2 lobes: posterior lobe and larger more distinct anterior lobe

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12
Q

neuroendocrine cells

A

function as both nerve cells and endocrine cells, because they can generate nerve impulses and secrete hormones into blood vessels

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13
Q

antidiuetic hormone (ADH)

A

or oxytocin made in the hypothalamus and then transport the hormones down the axon for storage in axon endings in the posterior pituitary. regulates water balance. kidneys

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14
Q

Oxytocin

A

Uterus and mammary glands. induces uterine contractions and ejection of milk from mammary glands.

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15
Q

anterior pituitary produces 6 key hormones

A
  1. Adrenocorticotropic hormone (ACTH) - adrenal cortex, stimulates adrenal cortex to release glucocorticoids
  2. Thyroid-stimulating hormone (TSH) - stimulates synthesis and secretion of throid hormones
  3. Follicle-stimulating hormone (FSH) - stimulates egg maturation and formation of sperm
  4. Luteinizing hormone (LH) - stimulates ovulation and testosterone secretion
  5. Prolactin (PRL) - stimulates the development of mammary gland cells and prodcution of milk.
  6. Growth hormone (GH) - stimulate4s growth in young individuals; plays multiple roles in cell division, protein synthesis, and metabolism n adults
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16
Q

pancreas

A

is both endocrine (secreting hormones into the blood) and exocrine gland (secreting enzymes, fluids and ions into the digestive tract to aid in digestion).

17
Q

3 types of cells and 3 hormones produced (pancreas)

A
  1. alpha cells secrete glucagon, which raises blood sugar. Glucagon breaks down glycogen in liver.
  2. betta cells secrete insulin, which lowers blood sugar.
  3. delta cells secrete somatostatin. also secreted by hypothalmus
18
Q

adrenal glands

A

2 small endocrine organs located just above the kidneys. each gland has an outer layer called adrenal cortex and an inner core calle adrenal medulla

19
Q

Cortisol

A

accounts for approximately 95% of glucocorticoids. it assists in maintaing blood glucose levels by promoting the utilization of fats and by increasing the breakdown of proein to amino acids in muscle.

20
Q

aldosterone

A

Mineralocorticoids. is the hormone primarily responsible for regulating the amounts of sodium and potassium in the body. it increases when sodium and water are too low. potassium is too much

21
Q

adrenal medulla

A

produces the nonsteriod hormones epinephrine (adrenaline) and norepinephrine (noradrenaline). play roles in metabolism and controling blood pressure and heart activity

22
Q

Epinephrine and norepinephrine

A

contribute to the fight-orflight response intiated by the sympathetic nervous system.

23
Q

thyroid gland

A

situated just below the larynx at the front of the trachea and the 2 lobes of the thyroid gland wrap part of the way around the trachea. control metabolism. produce throxine and calcitonin

24
Q

parathyroid glands

A

are embedded in the back of the thyroid. both control calcium balance. produce parathryoid hormone

25
Q

thyroxine (T4)

A

contains 4 molecules of iodine. not steriod hormone structurally but acts like one because its lipid soluble. increases production and use of ATP

26
Q

Calcitonin

A

promotes bone growth.

27
Q

parathyroid hormone 3 functions

A
  1. removes calcium and phosphate from bone
  2. increases absorption of calcium by the digestive tract
  3. causes the kidneys to retain calcium and excrete phosphate
28
Q

thymus gland

A

located between the lungs, behind the breastbone and near the heart. secretes several peptide hormones that assist in the development of lymphocytes into mature T cells.

29
Q

pineal gland

A

located deep within the brain, in the roof of the third ventricle. brain’s “third eye”

30
Q

melatonin

A

secreted by pineal gland, “hormone of darkness”

31
Q

3 organs and what they secrete

A
  1. atrial natriuretic hormone (ANH) is a non steriod hormone secreted by the atria of the heart that helps regulate blood pressure
  2. gastrin, secretin and cholecystokinin are allhormones secreted by the digestive system.
  3. erythropoietin and renin are secreted by the kidneys
32
Q

Histamine

A

important in inflammation. increases secretion of mucus, dilates blood vessels, increases leakiness of capillaries

33
Q

prostaglandins

A

control local blood flow; constrict blood vessels, dilate blood vessels, contribute to inflammatory response and blood clotting

34
Q

Diabetes mellitus

A

inadequate control of blood sugar. type 1 - caused by the failure of the pancreas to produce enough insulin. type 2 - represents 90-95% of all cases. its hallmark is insulin resistance. cells fail to respond adequately to insulin even when it is present

35
Q

hypothyroidism

A

underactive thryoid gland

36
Q

hyperthyroidism

A

overactive thryoid gland

37
Q

addison’s disease

A

too little cortisol and aldosterone

38
Q

cushing’s syndrome

A

too much cortisol