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biology > Chapter 13,14&15 communication and homeostasis > Flashcards

Chapter 13,14&15 communication and homeostasis Flashcards

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1
Q

why do we need communication systems?

A

changing external environments
changing internal environments
co-ordinating different organs

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2
Q

how do changing external environments impact organisms

A

change places stress on the living organism
the environment change is a stimulus and the way the organism changes its behaviour or physiology is its response
abiotic - temperature
biotic - predator/prey interactions

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3
Q

why do we need a constant internal environment

A

all living things need to maintain a certain limited set of conditions inside cells to ensure optimum conditions for enzyme action

suitable temperature, pH, Aqueous environment, no toxins/ inhibitors

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4
Q

what are the features of a good communication system

A

whole body
cell communication
specific
rapid
short and long term

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5
Q

what are the two ways cells communicate with each other

A

neuronal - network of interconnecting neurones that produce rapid responses to changing stimuli

hormonal - uses the blood to transport hormones from endocrine glands to target organs. can be used to produce longer term responses

both systems utilise cell surface receptors, with specific shapes, to enable receipt of cell signals

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6
Q

define cell body

A

nucleus and large amounts of RER associated with production of proteins and neurotransmitter

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7
Q

what is the function dendrons (dendrites)

A

carry nerve impulses towards the cell body

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8
Q

define axon and its function

A

single long fibre that carries nerve impulses away from the cell body

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9
Q

define schwann cells

A

surround axon by wrapping around many times, protecting it and providing electrical insulation
phagocytosis and nerve regeneration

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10
Q

what is the function of the myelin sheath

A

forms covering of axon and made of membranes of the schwann cells.
rich in a lipid known as myelin
myelinated neurones transmit nerve impulses faster

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11
Q

define the “Nodes of Ranvier”

A

gaps between adjacent schwann cells where there is no myelin sheath. gaps 2-3um and occur every 1-3mm

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12
Q

what are the 3 types of neurone

A

sensory
relay
motor

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13
Q

what is the function and structure of sensory neurones

A

transmit impulses from a sensory receptor cell to a relay neurone, motor neurone or the brain.
They have one dendron, which carries the impulse to the cell body, and one axon which carries the impulse away from the cell body
sensory neurones are unipolar - one process coming off the cell body)

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14
Q

what is the function and structure of relay neurones

A

these neurones transmit impulses between neurones. E.g. between sensory neurones and motor neurones, they have many short axons and dendrons

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15
Q

what are the similarities and differences between motor and sensory neurones

A

similarities:
both have axon terminals
both have dendrites
both have cell bodies

differences:
s=unipolar, m=multipolar
s= has a dendron
s= connected to CNS/relay neurone, m=connected to motor end plate
motor’s axon is longer, s=shorter axon

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16
Q

what is the function and structure of motor neurones

A

neurones transmit impulses from a relay neurone or sensory neurone to an effector such as a muscle or a gland. they have one long axon and many short dendrites (multipolar)

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17
Q

what is the nervous response’s electrical impulse pathway

A

receptor -> sensory neurone -> relay neurone -> motor neurone -> effector cell

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18
Q

what is the function of the myelin sheath in myelinated neurones

A

electrical impulse “jumps” from one node to the next as it travels along the neurone. allows the impulse to be transmitted much faster

also the myelin sheath is made of lipoprotein (myelin) which means ions remain in the neurone - cannot diffuse out as not water soluble.

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19
Q

define ectotherm

A

an organism whose body temperature fluctuates with external temperatures

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20
Q

what are the advantages and disadvantages of ectotherms

A

advantages: use less food in respiration
need less food
greater energy proportion used for growth

disadvantages: less active in cooler temperatures
may not be capable of activity in winter months

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21
Q

define endotherms

A

organisms which use internal sources of heat to maintain body temperature.
many chemical reactions in the body are exergonic (release heat)
endotherms show behavioural and physiological adaptations

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22
Q

what are the physiological adaptations of endotherms to regulate temperature

A

too hot - secrete more sweat, panting, lie flat, vasodilation, reduce rate of metabolism

too cold - less sweat secreted, no panting, raised/ increased movement, vasoconstriction, increased rate of metabolism, spontaneous contractions/ shivering

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23
Q

what are endotherms’ behavioural adaptations to regulate temperature

A

too hot - move to shade, increased exposed surface area, remain inactive

too cold - move to sunlight, decreased exposed surface area, move to generate heat in muscles, roll into ball - decrease surface area

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24
Q

what are the advantages and disadvantages of endotherms

A

advantages - constant optimal body temperature
activity possible even when cold
inhabit colder parts of the planet

disadvantages - energy used up to maintain temperature
more food required
less energy used in growth

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25
how do endotherms monitor the temperature of the blood
using the thermoregulatory centre in the hypothalamus of the brain
26
what are peripheral temperature receptors
receptors in the skin monitor the temperature in the extremities and feed information to the thermoregulatory centre
27
what are effector cells and what is their role in vasodilation/ constriction
smooth muscle in arterioles and pre-capillary sphincter muscles at the skin surface relax to dilate and contract to constrict
28
what is the purpose of increasing vessel diameter
increased blood flow to the skin and in turn the amount of heat lost by radiation to the air
29
how does sweating reduce body temperature
stimulated by motor neurones from hypothalamus effector cells in sweat glands as water has high latent heat of vaporisation, a significant amount of heat energy is lost
30
how do hairs and feathers regulate body temperature
too cold - erector muscles contract to raise hairs/ feathers trapped air acts as an insulator reducing heat loss too hot - erector muscles relax - hairs/ feathers lie flat insulation reduced so more heat lost to air by radiation
31
how does metabolic activity change if temperature is too low
thyroid and adrenal glands release thyroxine and adrenaline to increase metabolic activity leading to more exogenic reactions and more heat released involuntary muscle spasm (shivering) causing more respiration and therefore release more heat
32
what is the process of transmission of an action potential in UNmyelinated neurones
1. Na+ ion diffuses into the neurone through a channel 2. there is a localised high concentration of Na+ inside the neurone 3. Na+ diffuses along the inside of the neurone 4. Na+ gate, initially closed, opens due to depolarisation 5. there is a series of 'local circuits' or 'currents'
33
what is the process of transmission of action potential in myelinated neurones
1. ionic changes can only occur at the "Nodes of Ranvier" as Na+ and K+ gated channels are found here 2. Na+ and K+ ions cannot diffuse through myelin 3. there are elongated total circuits/ currents 4. action potential 'jumps' from one node to the next 5. called saltatory conduction
34
what are the advantages of the myelin sheath in neurones
insulates speeds up transmission fewer channels needed (less protein, amino acid, ATP etc)
35
what effects the speed of an impulse in neurones
myelin sheath - increases speed axon diameter - greater diameter= faster temperature - higher temperature= faster speed temperature also effects rate of diffusion of ions
36
what happens to an impulse in neurones of temperature is too high
channel denatures and impulse not transmitted
37
what is the synapse
the gap between the presynaptic and postsynaptic neurones synaptic vesicles contain neurotransmitters to be transported across the synapse
38
what are the 5 examples of neurotransmitters
1. Acetylcholine (ACh) - cholinergic synapse 2. noradrenaline 3. dopamine 4. glutamic acid 5. serotonin
39
what are the key features of synapses
synaptic cleft - gap which separates the axon of one neurone from the dendrite of the next (20-30nm across) presynaptic neurone - neurone along which the impulse has arrived postsynaptic neurone - neurone that receives the neurotransmitter presynaptic knob - the swollen end of the presynaptic neurone - contains many mitochondria and ER to enable it to manufacture neurotransmitters synaptic vesicles - vesicles containing neurotransmitters neurotransmitter receptors - receptor molecules which the neurotransmitter binds with in the postsynaptic membrane
40
what are the types of neurotransmitter
excitatory - result in the depolarisation of the postsynaptic neurone. If the threshold is reached in the postsynaptic membrane an action potential is triggered. eg. acetylcholine inhibitory - result in the hyperpolarisation of the postsynaptic membrane. preventing action potential from being triggered. eg. gamma-aminobutyric acid (GABA)
41
what are the 7 features of synapses
1. several presynaptic neurones "converge" to one postsynaptic neurone 2. one presynaptic neurone "diverges" into several postsynaptic neurones 3. unidirectionality - message can only be sent from pre to post synaptic neurones 4. filter out low level stimuli 5. acclimatisation - background sounds or smells repeated stimulation results in "fatigued" synapse 6. summation - pick up multiple stimuli for enough neurotransmitter to generate action potentials (spatial or temporal) 7. inhibition - there are chloride ion channels on the postsynaptic membrane, if Cl- ions flood into the postsynaptic membrane, it can become hyperpolarised - unable to achieve an action potential
42
what are the two types of summation
spatial - different presynaptic neurones share the same synaptic cleft (convergent) - multiple neurones temporal - a single presynaptic neurone releases many neurotransmitter over a short period of time (one neurone) - total amount exceeds the threshold value
43
state the: stimulus example of receptor and example of sense organ for a "mechanoreceptor"
stimulus = pressure and movement receptor = Pacinian corpuscle sense organ = skin
44
state the: stimulus example of receptor and example of sense organ for a "chemoreceptor"
stimulus = chemicals receptor = olfactory receptor (detects smells) sense organ = nose
45
state the: stimulus example of receptor and example of sense organ for a "thermoreceptor"
stimulus = heat receptor = end-bulbs of Krause sense organ = tongue
46
state the: stimulus example of receptor and example of sense organ for a "photoreceptor"
stimulus = light receptor = cone cell (detects different light wavelengths) sense organ = eye
47
what are the two features of sensory receptors
act as transducers - convert a stimulus into a nerve impulse they are specific to a single type of stimulus
48
describe the basic structure of a Pacinian corpuscle
single nerve fibre surrounded by layers of connective tissue which are separated by viscous gel and contained by a capsule stretch-medicated Na+ channels on plasma membrane capillary runs along base layer of tissue
49
what stimulus does a Pacinian corpuscle respond to? and how?
pressure deforms membrane, causing "stretch-mediated Na+ ion channels" to open if influx of Na+ raises membrane to threshold potential, a generator potential is produced. action potential moves along sensory neurone
50
what are the 3 processes Schwann cells are involved in?
electrical insulation phagocytosis nerve regeneration
51
where are myelinated neurones found in the body
most in central and peripheral nervous systems
52
where are non-myelinated neurones found in the body
group C nerve fibres involved in transmitting secondary pain
53
name the stages in generating an action potential
1. depolarisation 2. repolarisation 3. hyperpolarisation 4. return to resting potential
54
explain the importance of the refractory period
no action potential generated ensures unidirectional impulse ensures discrete impulses limits frequency of impulse transmission larger stimuli have higher frequency
55
how do neurotransmitters pass across the synaptic cleft
simple diffusion
56
why is the pancreas both endocrine and exocrine?
exocrine - secretes digestive enzymes into pancreatic duct endocrine - secretes hormones directly into blood (insulin and glucagon)
57
what is the islet of langerhans in the pancreas
cluster of beta and alpha cells that secrete hormones
58
what are acini in the pancreas
cluster of acinus cells surrounding a tubule in the centre acinus cells secrete enzymes - exocrines
59
what do alpha cells do in the pancreas
manufacture and secrete glucagon
60
what do beta cells do in the pancreas
manufacture and secrete insulin
61
what is pancreatic juice made up of
amylase (type of carbohydrase) trypsinogen (inactive protein) lipase
62
define genesis
to make
63
define lysis
to break
64
define -neo
new
65
define glycogenolysis
the breakdown of glycogen into glucose
66
define glycogenesis
the formation of glycogen to glucose
67
how do beta cells manufacture insulin (8 steps)
1. potassium and calcium ion channels on cell membrane 2. K+ channels normally open so K+ diffuses out 3. stimulus - causes blood glucose to rise, glucose diffuses into cell 4. glucose metabolised into ATP 5. ATP closes the K+ ion channels 6. accumulation of K+ ions alters the potential difference - inside the cell is less negative 7. change in P.D. causes voltage gated Ca+ channels to open 8. Ca+ ions diffuse into cell and cause vesicles containing insulin to fuse with plasma membrane and insulin is released - exocytosis
68
what happens in the pancreas when blood glucose levels are raised
alpha cells decrease glucagon secretion beta cells increase insulin secretion target cells = Hepatocytes - liver cells muscle cells adipose (fat cells) brain cells action 1. more glucose channels on membrane 2. more glucose enters cell 3. glucose into glycogen (glycogenesis) 4. glucose converted into fats 5. more glucose used in respiration blood glucose decreases
69
what is the non-steroid hormone mechanism
hydrophilic the hormone is the FIRST MESSENGER binds to receptors on the cell surface membrane (complimentary) - cannot pass directly through the cell membrane G protein is activated - activates an enzyme ADENYL CYCLASE adenal cyclase converts ATP to cAMP cAMP = second messenger cAMP acts directly on another protein, stimulate change and initiates a "cascade of enzyme controlled reactions"
70
what is the mechanism for steroid hormones
lipid soluble pass through plasma membrane bind to receptors in the cytoplasm or nucleus - forms hormone-receptor complex complex acts as a transcription factor either facilitating or inhibiting the transcription of a specific gene
71
what are the 3 layers in adrenal glands - outer to inner
outer = capsule middle = cortex inner = medulla
72
what hormones are produced by the adrenal cortex and how?
- uses cholesterol to produce steroid hormones ALSOSTERONE (mineralocorticoid) - controls Na+ and K+ levels via the kidney and impacts water retention and blood pressure CORTISOL (glucocorticoid) controls metabolism in the liver decreasing the synthesis of glycogen from glucose precursor molecules of the sex hormones also produced
73
what hormones are secreted by the adrenal Medulla and why
secretes adrenaline in response to stress - prepare body for "fight or flight"
74
how does adrenaline effect the body
relaxes smooth muscle in bronchioles - larger diameter for more air - O2 needed for respiration - more energy increases stroke volume of the heart and heart rate- transports more O2 and glucose for more respiration vasoconstriction (general) - increases blood pressure - restricts blood flow - sends blood to vital brain and muscles stimulates breakdown of glycogen - more glucose more respiration pupils dilate - more light enters eyes - increased vision increased mental awareness - make faster decisions as more energy into the brain so more neurotransmitters firing action potentials inhibits action of the gut - diverts blood away via vasoconstriction to more essential organs
75
what is the official name for diabetes
diabetes mellitus
76
what is the name for high blood glucose
hyperglycaemia
77
what is the name for low blood glucose
hypoglycaemia
78
what are the causes of type 1 diabetes mellitus
unable to produce insulin may arise due to an autoimmune response - immune system destroys beta cells usually developed during early childhood
79
what are the causes of type 2 diabetes mellitus
develops later in life body stops responding to insulin or beta cells don't produce enough insulin resistance - receptors (glycoprotein) do not work cells lose responsiveness to insulin therefore do not take up glucose, glucose left in the blood stream "everyone will eventually get it as body deteriorates" chances increased by: excess body weight physical inactivity excessive overeating of refined carbohydrates
80
what is the treatment for type 1 diabetes mellitus
regular blood glucose monitoring - analysed by machine insulin injections - increased glycogenesis
81
what is the treatments for type 2 diabetes mellitus
regulation of carbohydrate intake exercise weight loss drugs - stimulate insulin production insulin injections
82
what are the past, present and future sources for manufactured insulin
past: extracted from pancreas of animals eg. pigs present: genetically engineered bacteria future: stem cell therapies - promote embryonic stem cells to differentiate into beta cells
83
what are the advantages of using genetically engineered bacteria to produce insulin for injections
cost effective - higher quantities produced removes ethical concerns over using animals or embryonic stem cells pure form therefore less likely to produce allergic reactions/ rejection
84
what are the advantages and disadvantages of stem cell therapy for diabetes mellitus
advantages: donor availability wouldn't be an issue reduced likely-hood of rejection - less immune response removal of need for patients to inject insulin disadvantages: do not yet know how to control growth and differentiation - could cause tumours due to unlimited cell growth embryonic stem cells - must destroy embryo - ethical obligations
85
what two hormones promote glycogenolysis
glucagon and adrenaline (during the fight or flight response)
86
where are the glands that secrete steroid hormones eg. Corticosteroids found?
in the cortex/ cortical region
87
describe the sequence of events leading up to the secretion of insulin by beta cells
1. glucose respired (metabolized) to produce ATP. 2. ATP closes potassium ion channels so K+ build up inside cell and cannot leave 3. Voltage gated calcium ion channels open and calcium ions enter cell by diffusion 4. More calcium ions result in movement of vesicles to membrane/ exocytosis - insulin leaves cell - is secreted
88
after an initial release of insulin, why does insulin secretion continue even when there is no further glucose intake?
1. Because as long as blood glucose concentration remains higher than normal, 2. sufficient ATP is still present and so K+ channels remain closed 3. exocytosis still being triggered by calcium ions
89
describe two similarities in the action of plant and animal hormones in cell signalling
1. hormone binds to receptor causing cascade of events/ enzyme reactions 2. hormones only needed in small quantities/ concentrations to have an effect.
90
explain why plants are more able to form natural reproductive clones than animals
most plant cells retain ability to differentiate - totipotent plants have meristematic tissue plants can de-differentiate then differentiate into a different cell type most animal cells are differentiated/ not totipotent or pluripotent - only able to differentiate into the same type of cell - multipotent
91
define saltatory conduction
where action potential jumps from one node of Ranvier to the next

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