Chapter 12: Enzymes

Question 1

________ - is made up of protein and has the suffix “ase”. Very efficient and quick acting substances which increase rate of a reaction by decreasing Activation Energy.

Answer 1

enzyme

Question 2

____________ - “Active Site” of an enzyme resulting in formation of enzyme-substrate complex.

Answer 2

reactant or substrate binds

Question 3

__________ - Is an organic substance, which binds to and activates an enzyme sometimes, necessary for activation of an enzyme.

Answer 3

Cofactor

Question 4

___________ - The changes of enzyme shape upon binding of cofactor to enzyme.

Answer 4

conformational change

Question 5

What are examples of cofactors?

Answer 5

Example of cofactors: zinc and magnesium

Question 6

__________- - Is an organic molecule (cofactor) that directly participates as one of the reactants/substrates in the reaction.

Answer 6

Coenzymes

Question 7

What are the factors that increased enzymes rate of reaction?

Answer 7

Increasing substrate concentration

Increasing enzyme concentration

Using modulators ( changing enzyme activity or affinity )

Question 8

_____________- A metabolic pathway is a sequence of reactions that lead to formation of product(s).

Answer 8

Metabolic Pathways

Question 9

_____________ - slowest reaction in the metabolic pathway and determines the rate of the overall (sequence of) reaction.

Answer 9

Rate-limiting reaction

Question 10

______________ - Term used to describe inhibition of a metabolic pathway by inhibition or decrease in activity of (usually) the rate-limiting enzyme.

Answer 10

End-product inhibition