Chapter 12 Flashcards
nucleic acid sequence info used to classify bacteria
classification
to further characterize bacterial species
genotyping
controls for amplification
homologous extrinsic
controls for extraction and amplification
heterologous extrinsic
human gene control
heterologous intrinsic
-static
inhibit growth
-cidal
kill organisms
what is now considered the gold standard when phenotype assays are being developed
molecular methods
rapidly spreading outbreak of infectious disease
epidemic
a disease that sweeps across wide geographical areas
pandemic
collection and Analysis of environmental, microbiology, and clinical data
epidemiology
measures biological characteristics of organisms
phenotypic analysis
a genotypic analysis targeting genomic or plasmid DNA
molecular epidemiology
PCR amplification priming outward from repetitive element generate what products
strain specific products
viruses of detection include antibody detection, antigen detection, or culture
classical methods
viruses of detection include Target, probe, and Signal amplification
molecular methods
number of viruses per milliliter of fluid
viral load
lowest level detected at least 95% of the time
sensitivity
ability to determine True Value
accuracy
reproductibiliy of independently determine test results
precision
negative samples are always negative and positive results are true positives
specificity
a Serial dilution of standard curve closely approximates a straight line
linearity
accuracy of measurement of virus regardless of sequence variations
flexibility
what genes mutate to overcome antiviral agents
viral genes
