Chapter 11 Flashcards
What percentage of an adults body weight comes from water
60%, varies by age
What does fluid do in the body
-Carries nutrirents and waste products
-Maintains the structure of large molecules
-participates in metabolic reactions
-serves as a solvent
-acts as a lubricant and cushion
-aids in regulation of body temperature
-maintains blood volume
Intracellular fluids
fluid inside the cell
Interstitial fluid
Fluid surrounding the cell
Extracellular fluid
Fluid outside the cell
Intravascular fluid
Fluid within blood vessels (Plasma)
Electrolyte balance
Electrolytes attracts water and carry it with them, cell membranes are selectively permeable and allow for passage of of some molecules
Electrolytes predominantly outside cell
Sodium, chloride, and calcium
Electrolytes predominantly inside cell
Potassium, magnesium, phosphate, and sulfate
Antidiuretic Hormone
(ADH) signalled by the hypothalamus, released in response to thirst
Renin
-Enzyme released by kidney cells when blood pressure is low, causes kidneys to reabsorb sodium, which is accompanied by water retention
- Hydrolyzes angiotensinogen to angiotensin I, inactive until converted to angiotensin II, which stimulates adrenal glands to release aldosterone, signalling kidneys to excrete potassium and retain sodium
Diarrhea/Vomiting
Water moving out of the cell, where salt goes, water flows
Reaction to low blood volume
Angiotensinogen and Renin (triggered by the hypothalamus) Turns inot angiotensin I - Angiotensin II (which constricts blood vessels) triggers ADH (retains water and thereby sodium, excretes potassium) and Aldosterone (retains sodium and excretes potassium thereby retains water) - Blood volume increases
Fluid Volume
Two thirds inside the cell , one third outside to cell
Dissociation of salt
Sodium- cation
Chloride: anion
conducts electricity, forms electrolyte solutions (positive and negative charges perfectly balanced
Acid and Base Balance
Body uses ions to regulate acidity (Narrow pH range to avoid life-threatening consequences, deviations can denature protein.) High concentration of hydrogne ions is acidic , a low concentration of ions is basic
Regulation of buffers
Buffers can neutralize acids or bases
Buffers in the body’s fluids (respiration)
Bicarbonate
Carbonic acid
Buffers in the body’s fluids (Excretion in kidneys)
Bicarbonate
Formation of Carbonic acid
carbon dioxide dissolved in water, lowers body’s pH (H2CO3)
Formation of bicarboniate ion
Carbonic acid dissociates to a hydrogen ion and a bicarbonate ion (HCO3-) which raises the body’s pH
Thirst and satiety
Mouth, hypothalamus, and nerves sense change, thirst response lags behind the body’s need for water (dehydration symptoms
Water intoxication
causes confusion, convulsions, and death, caused by drinking 10-20 litres within a few hours
Water balance health effects
physical and mental performance, proper functioning of kidneys, heart, GI tract, and other systems