chapter 10 Flashcards
Affects the hepatocytes and interferes with liver function..
Diffuse hepatocellular disease
Is a parenchymal liver cell that performs all the functions ascribed to the liver.
Hepatocyte
Is an acquired, reversible disorder of metabolism, resulting in an accumulation of triglycerides
Fatty Infiltration
Normal to elevated hepatic enzymes elevated Alk Phos elevated Direct bilirubin
Fatty Infiltration Clinical findings
Echogenicity Attenuation Impaired visualization of borders of portal/hepatic structures (secondary to increased attenuation) Hepatomegaly May be patchy, inhomogeneous Focal sparing
Fatty Infiltration Sonographic findings
Hepatitis
Cirrhosis
Metastases
Fatty Infiltration differential considerations
Elevated AST, ALT
Elevated Bilirubin
Leukopenia
Acute Hepatitis Clinical findings
Nonspecific and variable Normal to slightly elevated Echogenicity Increased brightness of portal vein borders Hepatosplenomegaly Increased thickness of gallbladder wall
Acute hepatitis Sonographic Findings
Fatty liver
Differential considerations Acute hepatitis
Elevated AST, ALT
Elevated bilirubin
Leukopenia
Chronic hepatitis Clinical findings
COarse hepatic parenchyma
Increased echogenicity
Decreased visualization brightness of portal triad
Fibrosis may produce soft shadowing
Chronic Hepatitis Sonographic findings
Cirrhosis
Fatty liver
Chronic Hepatitis Differential considerations
INcreased phos
Increased direct bilirubin
Increased AST, ALT
Leukopenia
Cirrhosis clinical findings
Coarse liver parenchyma with nodularity Increased echogenicity Increased attenuation Decresasd vascular markings with acute cirrhosis Hepatosplenomegaly with ascites Shrunken liver with chronic cirrhosis (also increased nodularity) Regeneration of hepatic nodules Portal hypertension
Sonographic findings Cirrhosis
Fatty liver
Hepatitis
Cirrhosis Differential considerations
Disturbance of acid-base balance
Glycogen Storage Disease Clinical findings
Hepatomegaly
Increased echogenicity
Increased attenuation
Von Gierek’s adenoma (Round, homogeneous)
Glycogen Storage Disease Sonographic findings
Focal nodular hyperplasia
Glycogen Storage Disease differential considerations
Increased Iron levels in blood
Hemochromatosis clinical findings
Increased echogenicity throughout live
Sonographic findings Hemochromatosis
Cirrhosis
Differential considerations hemochromatosis
Obesity Excessive alcohol intake (alcohol stimulates lipolysis Poorly controlled hyperlididemia Diabetes mellitus Excess corticosteriods Pregancy Total parenteral Hyperalimentation (nutrition) Severe hepatitis Glycogen storage disease Cystic fibrosis Pharmaceutical Chronic illness
Causes of fatty liver
Suspected portal hypertension secondary to liver disease
Portal vein compression thrombosis
Acute onset of hepatic vein occlusion (Budd-Chiari syndrome) constrictive pericarditis, or congestive heart failure with tricupsid regurgiatation
Congential, traumatic, or neoplastic arterioportal fistula
Indications for Portal hypertension
Develops when the normal venous channels become obstructed.
Collateral circulation
Ascites, right upper quadrant pain, hepatomegaly
Budd-Chiari syndrome Clinical findings
Increased caudate lobe atrophy in right lobe of the liver
Budd-Chiari syndrome Sonographic findings
Portal hypertension
Budd-Chiari syndrome Differential considerations