Chapter 1: Introduction to Pathology Flashcards

1
Q

Sequalae

A

Conditions resulting from a disease

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2
Q

Prevalence

A

A statistical measure that refers to the number of cases of a disease found in a given population

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3
Q

Syndrome

A

A group of signs and symptoms that occur together and characterize a specific abnormal disturbance

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4
Q

Traumatic

A

Pertaining to the effects of a wound or injury, whether physical or psychological

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5
Q

Virulence

A

The ease with which an organism overcomes body defenses

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6
Q

Genetic Mapping

A

A map assigning deoxyribonucleic (DNA) fragments to chromosomes.

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7
Q

Manifestations

A

Observable changes resulting from cellular changes in the disease process.

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8
Q

Metaplasia

A

Conversion of a specific type of tissue into a different kind of tissue.

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9
Q

Metastatic spread

A

The spread of cancer cells.

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10
Q

Which of the following terms refers to abnormal changes in mature cells?

A

Dysplasia

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11
Q

Hypertrophy

A

Increase in number of cells and tissue resulting in an increased organ size without the presence of a tumor.

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12
Q

Iatrogenic

A

Pertains to any adverse condition that occurs in a patient as a result of medical treatment.

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13
Q

Mortality Rate

A

Is the average number of deaths caused by a particular disease in a population

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14
Q

Autoantibodies

A

Antibody acting against its own tissue or organism.

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15
Q

Autoimmune Disorders

A

Disease in which antibodies form against and injure the patient’s own tissues, in contrast to the normal process in which antibodies form in response to foreign antigens.

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16
Q

Benign Neoplasm

A

A localized tumor of well-differentiated cells that does not invade surrounding tissue or metastasize to distant areas within the body.

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17
Q

Morphology

A

The form and structure of disease

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18
Q

Idiopathic

A

Having no identifiable causative factor.

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19
Q
  1. If 4000 cases of a given disease are found in a given population, the _______ of the disease is defined.
    a. Incidence
    b. Morphology
    c. Metabolism
    d. Prevalence
A

d. Prevalence

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20
Q

Degenerative

A

Refers to deterioration of the body usually associated with the aging process.

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21
Q

Diagnosis

A

The name of a disease an individual is believed to have.

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22
Q

Disease

A

Any abnormal disturbance of the normal function or structure of a body part, organ, or system; may display a variety of manifestations.

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23
Q
Sickness sufficient to interfere with normal daily routines is termed:
A: Etiology 
B: Morbidity
C: Mortality
D: Pathogenesis
A

B: Morbidity

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24
Q

Invasion

A

The prolapse of a segment of bowel into a distal segment

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25
Q

Lesion

A

General term used to describe the various types of cellular changes that can occur in response to a disease

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26
Q

Leukemia

A

A malignant disease of the leukocytes and their precursor cells in blood and bone marrow

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27
Q

A neoplasticism growth is evaluated to determine its degree of histologic differentiation. This is termed:

A. Grading
B. Metastasis
C. Morphology
D. Staging

A

Grading

28
Q

A DNA sequence variation occurring when a single nucleotide in the genome differs between members of a biological species or paired chromosomes in an individual

A

SINGLE-NUCLEOTIDE POLYMORPHISMS (SNPs)

29
Q

A type of tumor, often highly malignant, composed of a substance similar to embryonic connective tissue

A

Sarcoma

30
Q

Traveling of cancerous cells to a distant site or distant organ

A

SEEDING

31
Q

An objective manifestation of disease that is detected by the physician during examination

A

SIGN

32
Q

Any subjective evidence of a disease as perceived by the patient

A

SYMPTOM

33
Q

A compression fracture of the lumbar spine that results from steroid treatments for pain reduction of arthritis would be an example of ____________ disease.

a. Degenerative
b. Iatrogenic
c. Idiopathic
d. Traumatic

A

b. Iatrogenic

34
Q

Carcinoma

A

A malignant growth composed of epithelial cells that tends to invade surrounding tissues and give rise to metastasis

35
Q

Chronic

A

Presenting slowly and persisting over a long period of time

36
Q

Congenital

A

Existing at, and usually before, birth and resulting from genetic or environmental factors

37
Q
Review question three:
A disease such as Tay-Sachs syndrome that is transmitted genetically is termed:
a. Congenital 
b. Hereditary 
c. Metabolic
d. Neoplastic
A

B

38
Q

Neoplastic

A

Pertaining to new, abnormal tissue growth

39
Q

Morbidity Rate

A

The incidence of sickness sufficient to interfere with an individual’s normal daily routine

40
Q

Acute

A

Having a quick onset and lasting a short period of time with a relatively severe course

41
Q

Pathogenesis

A

Refers to the sequence of events producing cellular changes that ultimately leading to observable changes.

42
Q

Asymptomatic

A

Showing or causing no identifiable symptoms

43
Q

Atrophy

A

A reduction in size or a wasting of cells, tissues, or organs as a result of poor nutrition or nonuse

44
Q

Hematogenous Spread

A

Spread through the blood

45
Q

Physical mapping

A

A form of genetic mapping based on direct analysis of DNA , in which the physical distance between DNA, fragments are measured. This is used to assign DNA fragments to specific chromosomes.

46
Q

Hereditary

A

Genetically transferred from ethier parent to child & derived from ancestors

47
Q

Prognosis

A

The prediction of course and outcome for a given disease.

48
Q

Hyperplasia

A

Overdevelopment

49
Q

The prediction of the course and end of a disease and an outlook based on that prediction best define its:

A) Diagnosis
B) Etiology
C) Prognosis
D) Syndrome

A

C) Prognosis

50
Q

Genome

A

The entirety of an organism’s hereditary information, including both the genes and the non-coding sequences of DNA and ribonucleic acid

51
Q

Haplotype

A

A combination of DNA sequences at adjacent locations on the chromosome that are transmitted together

52
Q

A disease that manifests slowly and is present for a long period is said to be?

A

Chronic

53
Q
Review Question #7: Which of the following disease classifications is usually associated with the normal aging process? 
A. Congenital
B. Degenerative
C.Inflammatory
D. Metabolic
A

B. Degenerative

54
Q

Nosocomial

A

Originating or taking place in a hospital, acquired in a hospital, especially in reference to an infection.

55
Q

Incidence

A

A statistical measure that refers to the number of new cases of a disease found in a given period of time.

56
Q

Infection

A

An inflammatory process caused by exposure to some disease-causing organism.

57
Q

Inflammatory

A

Refers to the body process of destroying, diluting, or walling off a localized injurious agent.

58
Q

Lymphatic spread

A

Spread through the lymphatic system.

59
Q

Lymphoma

A

Neoplasticism growth in the lymphatic system.

60
Q

Malignant neoplasm

A

A lesion that grows, spreads, and invades other tissues.

61
Q

Generalized increase in cell size refers to?

A

Hyperplasia

62
Q
Review Question 5:
Which of the following would be considered a symptom of a disease process?
A. Bloody stool
B. Nausea
C. Skin Rash
D. Swelling
A

B. Nausea

63
Q

Dysplasia

A

the abnormal growth or development of a tissue or organ.

64
Q

Etiology

A

The cause or origin of the disease

65
Q

Epidemiology

A

Study and control of disease or injury patterns in human populations

66
Q

Review Question 9:

The relative ease with which an organism can overcome normal bodily defenses refers to its: 
A. Infection 
B. Necrosis 
C. Pestilence 
D. Virulence
A

D. Virulence.