Chapter 1- Introduction Flashcards

1
Q

What are the levels of organization and the related fields of study?

A

1) . Chemistry (atoms & molecules)
2) . Molecular Biology (cells & molecules)
3) . Cell Biology (molecules, cells, tissues)
4) . Physiology (molecules, cells, tissues, organs, organ systems, organisms, populations)
5) . Ecology (everything & ecosystems of different species &a biosphere)

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2
Q

Consists of heart, blood vessels, & blood

Functions to transport materials between all cells of the body

A

Circulatory system

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3
Q

Stomach, intestine, liver, pancreas

Functions to convert food into particles that can be transported into the body; elimination of some wastes

A

Digestive system

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4
Q

Thyroid gland, adrenal gland

Function: coordination of body function through synthesis and release of regulatory molecules

A

Endocrine system

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5
Q

Thymus, spleen, lymph nodes

Functions to defend against foreign invaders

A

Immune system

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6
Q

Skin

Protection from external environment

A

Integumentary system

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7
Q

Skeletal muscles and bone

Support and movement

A

Musculoskeletal system

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8
Q

Brain & spinal cord

Coordination of body function through electrical signals and release of regulatory molecules

A

Nervous system

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9
Q

Ovaries, uterus, testes

Perpetuation of species

A

Reproductive system

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10
Q

Lungs and airways

Exchange of oxygen and carbon dioxide between the internal and external environments

A

Respiratory system

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11
Q

Kidneys and bladder

Maintenance of water and allures in the internal environment; waste removal

A

Urinary system

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12
Q

Function is the “why” or the adaptive significance of the event

Thinking about the adaptive significance

A

Teleological approach

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13
Q

Examines the process, the “how”

A

Mechanistic approach

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14
Q

What are the themes in physiology?

A

1) . Structure & function (form fits function)
- molecular interactions
- compartmentation
2) . Energy storage, transfer, and use
3) . Information flow within the species, organism, and cell
4) . Homeostasis
- stability of internal environment

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15
Q

Organ systems in the body work to keep the internal environment constant despite changes in the external environment

A

Homeostasis

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16
Q

What does the body’s internal environment consist of?

A

Extracellular fluid (ECF- closely regulated by the body)

Intracellular fluid (ICF)

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17
Q

What separates the cell from the ECF?

A

Cell membrane

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18
Q

What goes in must come out

Open system

Output must equal input

Existing body load + intake or metabolic production - exertion or metabolic removal

A

Mass balance law

19
Q

From outside the body (food, drink, gasses, lipids)

From inside the body (metabolism, CO2)

A

Intake/input

20
Q

Excretion (urine, feces, lungs, skin)

21
Q

Any foreign substance in the body

A

Xenobiotic

22
Q

Use to follow material throughout the body

=concentration of (y) x volume flow

23
Q

The rate at which a substance disappears from the blood

Volume of (x) cleared per unit of time (indirect measure)

24
Q

Physiological normal range

25
What are the two groups of control mechanisms?
1) . Local (paracrine) | 2) . Long-distance, reflex control (endocrine and nervous)
26
What are the basic components of all control systems?
1) . Input signal 2) . Integrating center 3) . Output signal - creates response
27
How do cells in local control respond?
Cells in the vicinity of the change initiate the response
28
How do cells respond in reflex control?
Cells at a distant site control the response
29
Type of response loop Homeostatic
Negative feedback loops
30
Type of feedback loop Not homeostatic
Positive feedback loop
31
When the response of a system goes in a direction opposite to the change that set it in motion The response counteracts the stimulus, shutting off the response loop
Negative feedback
32
When the response of a system goes in the same direction as the change that set it in motion The response reinforced the stimulus, sending the variable farther from the setpoint
Positive feedback
33
When the response loop starts in anticipation of the change Ex- salivation
Feedforward
34
Changes in the set point of a regulated variable Ex- circadian rhythm
Biological rhythms (biorhythms)
35
Quantified the distribution of one variable over a range of values
Histogram
36
Each point represents one member of a test population Points never connect by lines Has best fit line
Scatter plot
37
When the individual is both the experimental subject and control Reduce variability
Crossover study
38
Subjects don't know during the study
Blind study
39
Third party knows what is happening during the study
Double blind
40
Control first half switch to experimental group and vice verses No one involved knows who is taking the active treatment
Double blind crossover study
41
Make comparisons at a single point in time Allows researchers to compare many different variables at the same time
Cross sectional studies
42
Make comparisons over time Researchers can detect developments or changes in the characteristics of the target population at both the group and the indivisible level Can establish sequences of events
Longitudinal studies
43
Watch for outcomes during the study period and relates this to other factors such as suspected risk
Prospective studies
44
Looks backwards and examines exposure to suspected risk factors in relation to an outcome that is established at the start of the study
Retrospective study