Chapter 1 Flashcards
When does upper lip formation begin?
Weeks 6-7 in utero
What structures contribute to the formation of the upper lip?
Medial nasal processes and the maxillary processes
What structures contribute to the formation of the primary palate?
Merging of the medial nasal processes
What structures contribute to the formation of the secondary palate?
Maxillary processes/Palatal shelves
What is cleft lip?
Failure of fusion of the medial nasal process with the maxillary process
What is cleft palate?
Failure of fusion of the palatal shelves
What is the treatment protocol for cleft lip?
Rule of 10 - 10 weeks, 10 pounds, 10 gm %HM
True or False: Most developmental cases of orofacial clefts are cleft palate and cleft lip
True, most cases are combined CL + CP
True or False: Most syndromic cases of orofacial clefts are cleft lip and cleft palate
False, syndromic cases most commonly present as cleft palate only
What are characteristics of Pierre Robin Sequence ?
Cleft palate, Mandibular micrognathia, glossoptosis
What are the 4 common environmental factors that can cause nonsyndromic orofacial clefts?
Maternal alcohol or cigarrette use, folic acid deficiency, corticosteroid use, and anticonvulsant therapy
What are the other more rare orofacial clefts?
Lateral facial cleft, oblique facial cleft, median cleft of the upper lip
In what populations are orofacial clefts most common?
Native American (1/250), Asians (1/300), Caucasians (1/700), African Americans (1/1500)
What is a submucous palatal cleft?
This occurs when the palatal shelves fail to fuse, but the surface is still intact. It appears as a notch in bone, and has a bluish discoloration at the midline.
Who is often involved in the management of orofacial clefts? (There are 9)
Pediatricians, OMFS, ENT, Plastic surgeon, Pediatric dentist, Orthodontist, Prosthodontist, Speech pathologist, Geneticist
What are lip pits?
Mucosal invaginations
When lip pits occur at the corners of the mouth, what are they called?
Commissural lip pits
True or False: Commissural lip pits are NOT associated with facial or palatal clefts
True, and no treatment is required
Congenital invaginations near the median of the lower lip are called ____________.
Paramedian lip pits
What syndrome is assoicated with Paramedian lip pits?
Van der Woude syndrome
What are the characteristics associated with Van der Woude syndrome?
Paramedian lip pits, autosomal dominant, cleft lip and cleft palate
Describe double lip.
A redundant fold of tissue on the mucosal side of lip
What causes double lip? Does is usually occur on the upper or lower lip?
It can be congenital or acquired (due to trauma or oral habits), and usually occurs on the upper lip.
What syndrome is associated with double lip?
Ascher syndrome
What are the characteristics of Ascher syndrome?
Double lip, Blepharochalasis (eyelid edema), Nontoxic thyroid enlargement (which messes with fluid retention)
What are Fordyce Granules?
“Ectopic” sebaceous glands
Where and when do fordyce granules appear?
Buccal and labial mucosa. They usually appear during puberty, so are more common in adults.
Describe Leukoedema.
Typically appear as dffuse gray-white, milky, opalescent lesions found bilaterally on buccal mucosa that do not wipe off.
What is a clinical test for leukoedema?
Stretching the tissue. The white appearance disappears when the cheek is stretched.
What is the term for an abnormally small tongue?
Microglossia
What is the term when there is no tongue?
Aglossia
What is aglossia frequently associated with?
Hypoplasia of the mandible (micrognathia)
What is the term that describe an abnormally large tongue?
Macroglossia
What most frequently causes macroglossia?
Vascular malformations (hemangiomas), muscular hypertrophy (associated with down syndrome), and tumors
What are some signs or macroglossia?
Noisy breathing, drooling, difficulty is eating or speaking
What syndrome is macroglossia associated with?
Beckwith-Wiedmann syndrome, where patients have increased risk for several childhood tumors
Describe ankyloglossia
A developmental tongue abnormality characterized by a short, thick lingual frenum resulting in limitation of tongue movement
When would you normally treat ankyloglossia?
Frenotomy or frenuloplasty at 4-5, unless it is interferring or causing a problem. Also, this condition could be “self correcting” i.e. patient falls down and tears frenum.
Describe lingual thyroid
Failure of migration of primitive thyroid gland during development
Where is the lingual thryoid usually found?
Between the foramen cecum and the epiglottis
Is lingual thyroid more common in males or females?
Females
Why should you avoid biopsy of the lingual thyroid?
In most cases, it is the patients only functioning thyroid tissue, and there is a risk of hemorrhage
What are some symptoms of lingual thyroid and when do they arise?
Dysphagia, dysphonia, dyspnea. Symptoms usually arise during puberty, adolescence, pregnancy, or menopause.
Desrcibe fissured tongue.
Dorsum of tongue exhibits multiple grooves/furrows that can measure from 2-6 mm in depth.