Chapter 1 Flashcards
When does upper lip formation begin?
Weeks 6-7 in utero
What structures contribute to the formation of the upper lip?
Medial nasal processes and the maxillary processes
What structures contribute to the formation of the primary palate?
Merging of the medial nasal processes
What structures contribute to the formation of the secondary palate?
Maxillary processes/Palatal shelves
What is cleft lip?
Failure of fusion of the medial nasal process with the maxillary process
What is cleft palate?
Failure of fusion of the palatal shelves
What is the treatment protocol for cleft lip?
Rule of 10 - 10 weeks, 10 pounds, 10 gm %HM
True or False: Most developmental cases of orofacial clefts are cleft palate and cleft lip
True, most cases are combined CL + CP
True or False: Most syndromic cases of orofacial clefts are cleft lip and cleft palate
False, syndromic cases most commonly present as cleft palate only
What are characteristics of Pierre Robin Sequence ?
Cleft palate, Mandibular micrognathia, glossoptosis
What are the 4 common environmental factors that can cause nonsyndromic orofacial clefts?
Maternal alcohol or cigarrette use, folic acid deficiency, corticosteroid use, and anticonvulsant therapy
What are the other more rare orofacial clefts?
Lateral facial cleft, oblique facial cleft, median cleft of the upper lip
In what populations are orofacial clefts most common?
Native American (1/250), Asians (1/300), Caucasians (1/700), African Americans (1/1500)
What is a submucous palatal cleft?
This occurs when the palatal shelves fail to fuse, but the surface is still intact. It appears as a notch in bone, and has a bluish discoloration at the midline.
Who is often involved in the management of orofacial clefts? (There are 9)
Pediatricians, OMFS, ENT, Plastic surgeon, Pediatric dentist, Orthodontist, Prosthodontist, Speech pathologist, Geneticist
What are lip pits?
Mucosal invaginations
When lip pits occur at the corners of the mouth, what are they called?
Commissural lip pits
True or False: Commissural lip pits are NOT associated with facial or palatal clefts
True, and no treatment is required
Congenital invaginations near the median of the lower lip are called ____________.
Paramedian lip pits
What syndrome is assoicated with Paramedian lip pits?
Van der Woude syndrome
What are the characteristics associated with Van der Woude syndrome?
Paramedian lip pits, autosomal dominant, cleft lip and cleft palate
Describe double lip.
A redundant fold of tissue on the mucosal side of lip
What causes double lip? Does is usually occur on the upper or lower lip?
It can be congenital or acquired (due to trauma or oral habits), and usually occurs on the upper lip.
What syndrome is associated with double lip?
Ascher syndrome