chapter 1 Flashcards
Who identified a language disorder caused by reduced auditory comprehension instead of impaired expression
Wernicke in 1874
How much of the US population is estimated to have some form of a chronic or acquired neurologic disorder
More than 20% (50 million)
What is the leading cause of Aphasia?
Strokes (600-700 thousand people each year)
Vascular disorders
(thrombosis, embolism, hemorrhage)
Neoplastic conditions
(benign or malignant tumors)
Cortical degenerative diseases
(ALS, Pick disease, Alzheimers)
Myelin degeneration
(MS, Guillain-Barre syndrome
Motor disorders
(Parkinson, Huntington chorea)
Bacterial and viral infections
(meningitis, encephalitis)
Other diseases that disrupt the normal structural and physiological properties of the nervous system
Cellular toxicity (drugs)
Epileptic disorders
Traumatic brain injury
Surgical intervention to treat a disease of the nervous system
Removal of tumors
Extraction of blood clots
Excision of vascular aneurysms
Arteriovenous malformations
Neuroanatomy
Structural organization of the nervous system
Defines the structural elements of the nervous system
Neurons
Fiber tracts
Vascular networks
neuroradiology technology
X-ray Angiography CT scan computer tomography MRI magnetic resonance imaging SPECT single photon emission computed tomography PET positron emission tomography MEG magnetoencephalography
neuroembryology
Growth of the nervous system during the embryonic periods of development from conception to 7 weeks all brains structures have anatomically emerged and are in place by 7 weeks
Teratology
Teratology is the study of fetal malformations
neurophysiology
Focuses on the functional properties of the nervous system with respect to structural, chemical, and electrical composition
Neuropathology deals with the nature, cause and diagnosis of diseased tissue in the brain and spinal cord
Principles governing the human brain
- Interrconnectivity in the brain
- Centrality of the central nervous system
- Hierarchy of neuraxial organization
- Laterality of brain organization
- Functional networking
- Topographical representation
- Plasticity in the brain
- Culturally neutral brain
*Interrconnectivity in the brain
Allows the brain to connect messages to the other part of the brain.
What’s the largest connection in the brain?
Corpus Collosum
Centrality of the central nervous system
Everything is midlined. Your brainstem, spinal cord, is all central. Everything fuses center in utero.
Hierarchy of neuraxial organization
There are certain systems that are more important than others. Autonomic, chemical, visceral, and skin and all these systems together regulate blood pressure, body temperature, respiration, sleep)
Interconnectivity in the brain
Specific primary sensory and motor regions in the cerebrum are connected through association and commissural fibers
Cortical association areas are directly connected to each other
Primary cortical areas are ___________through the cortical association areas
Primary cortical areas are indirectly connected through the cortical association areas
The cortical association areas serve as _______ through which the primary cortical areas are ____________
The cortical association areas serve as a hub through which the primary cortical areas are indirectly connected
The two hemispheres are connected through the __________________ fibers
The two hemispheres are connected through the interhemispheric commissural fibers
Centrality of central nervous system
Cns integrates all incoming and outgoing information
- No two parts in the peripheral body can directly communicate with each other
- All forms of communication between the body and its parts is mediated through the CNS
Hierarchy in Neuraxial organization
- Spinal cord lowest level
- Brainstem and diencephalon intermediate level
- Cerebral cortex highest level
*The complexity of information processing increases as the level of processing becomes more brain controlled
Topographical representation (homunculus)
drawing of the brain to represent how much of the motor cortex controls certain functions of the body.
Plasticity in the brain
Also called neuroplasticity
- Ability to change as a result of experience
- Reorganize and gradually modify tissue functions when faced with pathologies
- Greatest in the early years and diminishes with age but never ends
Planes of brain section
Sagittal
Mid sagittal
coronal
Horizontal/transverse
sagittal
right and left halves
Mid sagittal
exactly equal (parasagittal would be not equal left and right halves)