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Laboratory Animal Technician > Chapter 1-4 Review > Flashcards

Chapter 1-4 Review Flashcards

1
Q

What is a research study?

A

a systematic investigation to establish facts

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2
Q

which of the following is a primary duty of the IACUC?

A

Review animal welfare concerns

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3
Q

True or False: researchers working for private companies do not need to compete for funding

A

false

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4
Q

Who makes the decision of how to handle any serious deficiencies found during post approval monitoring?

A

IACUC

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5
Q

Which entity in AALAC International approves an institution’s application for accreditation?

A

Council on Accreditation

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6
Q

Who must approve an animal use protocol before a study that involves animals can begin?

A

IACUC

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7
Q

a document that outlines the steps required to clean an animal room is called a:

A

standard operating procedure

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8
Q

Who are the main public granting agencies for scientific research?

A

NIH and NSF

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9
Q

Who monitors PHS Policy compliance?

A

OLAW

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10
Q

Per the AWR, how long can IACUC approve protocols for (for non-USDA covered animals)

A

1 to 3 years

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11
Q

How long can protocols containing USDA covered animals be approved for?

A

1 year

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12
Q

Who has the authority to withhold approval for an investigator to begin a research project?

A

IACUC

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13
Q

The USDA inspects research facilities for compliance with which mandates?

A

the Ag Guide, USDA policies, and AVMA guidelines

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14
Q

Why does the OLAW inspect research facilities

A

routinely and for cause (routine inspections of selected institutions, and potential noncompliance with the PHS policy)

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15
Q

who does the IACUC report to?

A

the IO, which in turn reports to the USDA, OLAW, AAALAC

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16
Q

What does PAM stand for?

A

post-approval monitoring

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17
Q

What does suspension of animal activities by the IACUC warrant?

A

notification to USDA, OLAW, and AAALAC

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18
Q

How often does AAALAC perform site visits?

A

every 3 years

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19
Q

which entity evaluates an institution’s animal research program based on semiannual reviews, annual reports, and three-year site visits?

A

AAALAC

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20
Q

When applying for AAALAC accreditation, the institution submits a detailed document outlining the animal care program called a ___

A

program description

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21
Q

Who is responsible for appointing members to the IACUC?

A

Chief executive officer

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22
Q

Who implements and enforces the Animal welfare act?

A

USDA

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23
Q

Who is responsible for conducting unannounced inspections of registered institutions within their respective regions?

A

USDA Veterinary Medical Officers (VMOs)

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24
Q

What did the USDA create to help institutions meet requirements for VMO visits?

A

Animal Care Inspection Guide

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25
Q

What is the IO referred to as in AWA and AWR?

A

chief executive officer

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26
Q

Who is responsible for monitoring compliance with the NIH Policy, Care, and Treatment of Laboratory Animals, now known as the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy)?

A

OLAW

27
Q

What must a federal grant or contract involving animals in the PHS policy submit before their grant or contract is approved?

A

Animal Welfare Assurance signed by the IO

28
Q

What does the Animal Welfare Assurance commit compliance to?

A

PHS policy, AVMA Guidelines, the Guide, and the AWA

29
Q

How many IACUC members does the PHS policy require?

A

5

30
Q

how many IACUC members does the AWA/R require?

A

3

31
Q

What agencies are responsible for AWR/A?

A

USDA, APHIS

32
Q

How long does an Assurance stay in effect?

A

4-5 years

33
Q

Which mandate includes the full text of the US Government principles for the Utilization and Care of Vertebrate Animals used in Testing, Research, and Training?

A

AWR/A, the Guide, and PHS Policy

34
Q

Although not a regulation, the Guide must be followed for research with animals covered by which mandate?

A

PHS

35
Q

What does the Guide take into consideration?

A

AWA, AWR, PHS Policy, and US Government Principles

36
Q

The Guide is a required mandate for which entities?

A

USDA for enforcement of the AWA, and AAALAC international for accreditation

37
Q

Who requires animal facilities to adhere to the AVMA’s guidelines for euthanasia?

A

USDA, OLAW, AAALAC

38
Q

What are the import requirements for laboratory rodents?

A

animals are shipped from the country of origin, appear health, have necessary export documents and proper identification, and enter the US through designated ports of entry

39
Q

What regulations apply to research or marketing permits for products regulated by the FDA and the EPA?

A

GLP

40
Q

Guidance for controlling laboratory animal allergy can be found in which document?

A

Occupational Health and Safety in the Care and Use of Research Animals

41
Q

Who can restrict or withdraw approval of the Animal Welfare Assurance if an institution fails at its responsibilites?

A

OLAW

42
Q

In the Guide, which word is defined as indicating a suggestion to be considered for the proper humane care and use of lab animals?

A

May

43
Q

The Guide holds which individual responsible for the veterinary oversight of the research program?

A

attending veterinarian

44
Q

What does the Guide acknowledge as determing the necessity for various functional areas in the physical plant of a research program?

A

scope and type of research conducted

45
Q

In the laboratory animal field, biosecurity refers to the protection of an animal colony from:

A

microbial contamination

46
Q

Which of the following is NOT an example of raw data for a GLP study?

A

health certificate

47
Q

___ means those actions taken to assure that laboratory animals are treated according to high ethical and scientific standards.

A

humane care

48
Q

___ is applied to research funded by federal grants and address some of the ethical concerns involved with research studies using animals.

A

US Government Principles

49
Q

when non-animal alternatives or less sentient species can take the place of animals without interfering with the objectives of the study

A

replacement

50
Q

using fewer animals in a study without altering the validity of the study

A

reduction

51
Q

can the procedures used in the study be changed to lessen pain and distress or minimize the number of potentially painful procedures

A

refinement

52
Q

Whistleblower protections are required by which regulation or guidelines?

A

AWR and the Guide

53
Q

What is not a method for the technician to support the ethical treatment of animals?

A

determining if the animal has reached the humane endpoint

54
Q

how long does PHS policy require that all assurance records related directly to grant applications, research proposals, and changes in research activities be maintained for at least, after completion of an activity?

A

3 years

55
Q

How long does the USDA require dog and cat tags to be kept after a study ends?

A

1 year

56
Q

Type of animal care program that is usually a separate department that serves all the institutions animal care needs and requests

A

centralized

57
Q

What type of management is where each department within the institute houses and uses lab animas for research or teaching and maintains its own animal facility and operating budget?

A

decentralized

58
Q

costs that can be attributed to a specific service or project (feed, bedding, labor)

A

direct

59
Q

costs that are required regardless of the service, project, or quantity and type of animals cared for (housekeeping, electricity, security, admin)

A

indirect costs

60
Q

A cost recovery analysis for technical services offered by the vivarium is based on what?

A

revenue for the services compared to expenses for related supplies and labor

61
Q

The NIH is a branch of which of the following?

A

PHS

62
Q

In addition to the federal, state, and local laws and regulations, what two documents are used by AAALAC in the US to evaluate institutions for accreditation?

A

The Guide and the Ag Guide

63
Q

Who is exempt from participating in the animal care training program?

A

no one

64
Q

Which federal mandate provides descriptions of shipping crate sizes and configurations for hamsters?

A

AWR

Laboratory Animal Technician (13 decks)

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