Chap. 7- bipolar Flashcards
BIP is _____ common than MDD
Less
About __% of the population, or __ million adults in the US are affected by BIP
0.7%, or 2.3 million
Risk for developing bipolar is increased by __% with a first-order relative with ___ or ___
25% increased with relative with
MDD or BIP 1
A first-order relative with BIP 2 represents a __% increased risk of developing BIP
5%
A diagnosable manic episode lasts at least __ days; a diagnosable hypomanic episode lasts at least __ days
7 days
4 days
BIP 1 is characterized by…
occurrence of one or more manic or mixed episodes
BIP 2 is characterized by…
occurrence of one or more depressive episodes accompanied by at least one hypomanic episode
Rapid cycling is defined as ____ or more mood episodes in the past __ months
4 or more in the last 12 months
Antidepressants may _____ mania or rapid cycling
Activate or accelerate
Just as with MDD, four labs to draw are…
CMP
CBC
B12
Thyroid panel
First manic episode after age 40 is most likely caused by…
Another medical condition
_____ are classic for activating mania
Steroids
You must not introduce a/an _____ without a _____ _____ on board and established first.
Antidepressant
Mood stabilizer
The gold standard for mania treatment
Lithium
Lithium has a _____ therapeutic index
Narrow
Lithium lab values
0.6-1.2 mEq/L
Lithium monitoring:
_____ function via _____ and _____
_____ function via _____ _____
_____ balance via _____
kidney function, BUN and creatinine
thyroid function, thyroid panel
electrolyte balance, CMP
Draw a lithium level __ hours post-dose
12 hours (trough level)
Lithium, used in pregnancy, is a known risk for _____ _____
Epstein’s anomaly
The three mood stabilizers requiring serum monitors
Lithium
Tegretol (carbamazepine)
Depakote (valproic acid)
Tegretol level normal
6 - 12 mcg/mL
VPA level normal
50 - 125 mcg/mL
Lamictal’s biggest risk
Stevens-Johnson syndrome
Topamax is also known as “dopamax” because of its…
Cognitive slowing
Tegretol’s ER formulation, known as Equetro, has the advantage of…
Not requiring serum monitoring
Two screens for BIP
YMRS (Young Mania Rating Scale)
MDQ (Mood Disorder Questionnaire)