Chap. 7- bipolar

Question 1

BIP is _____ common than MDD

Answer 1

Less

Question 2

About __% of the population, or __ million adults in the US are affected by BIP

Answer 2

0.7%, or 2.3 million

Question 3

Risk for developing bipolar is increased by __% with a first-order relative with ___ or ___

Answer 3

25% increased with relative with

MDD or BIP 1

Question 4

A first-order relative with BIP 2 represents a __% increased risk of developing BIP

Answer 4

5%

Question 5

A diagnosable manic episode lasts at least __ days; a diagnosable hypomanic episode lasts at least __ days

Answer 5

7 days

4 days

Question 6

BIP 1 is characterized by…

Answer 6

occurrence of one or more manic or mixed episodes

Question 7

BIP 2 is characterized by…

Answer 7

occurrence of one or more depressive episodes accompanied by at least one hypomanic episode

Question 8

Rapid cycling is defined as ____ or more mood episodes in the past __ months

Answer 8

4 or more in the last 12 months

Question 9

Antidepressants may _____ mania or rapid cycling

Answer 9

Activate or accelerate

Question 10

Just as with MDD, four labs to draw are…

Answer 10

CMP
CBC
B12
Thyroid panel

Question 11

First manic episode after age 40 is most likely caused by…

Answer 11

Another medical condition

Question 12

_____ are classic for activating mania

Answer 12

Steroids

Question 13

You must not introduce a/an _____ without a _____ _____ on board and established first.

Answer 13

Antidepressant

Mood stabilizer

Question 14

The gold standard for mania treatment

Answer 14

Lithium

Question 15

Lithium has a _____ therapeutic index

Answer 15

Narrow

Question 16

Lithium lab values

Answer 16

0.6-1.2 mEq/L

Question 17

Lithium monitoring:
_____ function via _____ and _____
_____ function via _____ _____
_____ balance via _____

Answer 17

kidney function, BUN and creatinine
thyroid function, thyroid panel
electrolyte balance, CMP

Question 18

Draw a lithium level __ hours post-dose

Answer 18

12 hours (trough level)

Question 19

Lithium, used in pregnancy, is a known risk for _____ _____

Answer 19

Epstein’s anomaly

Question 20

The three mood stabilizers requiring serum monitors

Answer 20

Lithium
Tegretol (carbamazepine)
Depakote (valproic acid)

Question 21

Tegretol level normal

Answer 21

6 - 12 mcg/mL

Question 22

VPA level normal

Answer 22

50 - 125 mcg/mL

Question 23

Lamictal’s biggest risk

Answer 23

Stevens-Johnson syndrome

Question 24

Topamax is also known as “dopamax” because of its…

Answer 24

Cognitive slowing

Question 25

Tegretol’s ER formulation, known as Equetro, has the advantage of…

Answer 25

Not requiring serum monitoring

Question 26

Two screens for BIP

Answer 26

YMRS (Young Mania Rating Scale)

MDQ (Mood Disorder Questionnaire)