Ch.22- The Respiratory System Flashcards

1
Q

The major function of the respiratory system is to…

A

supply the body with oxygen and dispose of carbon dioxide

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2
Q

What is the first stage of respiration and what occurs during this phase?

A

Pulmonary ventilation; air is moved into and out of the lungs

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3
Q

What is the second stage of respiration and what occurs during this phase?

A

External respiration; oxygen diffuses from the lungs to the blood and carbon dioxide diffuses from the blood to the lungs

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4
Q

What is the third stage of respiration and what occurs during this phase?

A

Transport of respiratory gases; oxygen is transported from the lungs to the tissue cells of the body, and carbon dioxide is transported from the tissue cells to the lungs

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5
Q

What is the fourth stage of respiration and what occurs during this phase?

A

Internal respiration; oxygen diffuses from blood to tissue cells, and carbon dioxide diffuses from tissue cells to blood

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6
Q

When does the lower respiratory system begin at?

A

the larynx and all structures below it

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7
Q

Name the 5 functions of the nose.

A

1) airway for respiration
2) moistens and warms entering air
3) filters and cleans inspired air
4) serves as a resonating chamber of speech
5) houses the olfactory receptors

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8
Q

What structure separates the nasal cavity from the oral cavity?

A

The palate (hard and soft)

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9
Q

What structure is located just superior to the nostrils and contains sebaceous and sweat glands and numerous hair follicles?

A

Nasal vestibule

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10
Q

What lines most of the nasal cavity?

A

Respiratory mucosa

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11
Q

What is the role of mucus?

A

to trap inspired dust, bacteria, and other debris. The mucus film also humidifies incoming air because of the high water content

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12
Q

What does a lysozyme do?

A

attacks and destroys bacteria

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13
Q

Natural antibiotics that help kill invading microbes

A

defensins

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14
Q

What benefit do the nasal conchae give?

A

they greatly increase the muscosal surface area exposed to air and enhance air turbulence in the cavity

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15
Q

What do the paranasal sinuses do?

A

they lighten the skull and may help warm and moisten the air

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16
Q

Inflammation of the nasal mucosa accompanied by excessive mucus production, nasal congestion, and postnasal drip

A

rhinitis

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17
Q

Inflamed sinuses

A

sinusitis

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18
Q

Where is mucus produced?

A

in the nose/nasal cavity

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19
Q

This structure connects the nasal cavity and mouth superiorly to the larynx and esophagus inferiorly

A

Pharynx

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20
Q

The pharynx is aka…

A

the throat

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21
Q

This part of the pharynx serves only as an air passageway

A

nasopharynx

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22
Q

During swallowing, what moves superiorly to close off the nasopharynx and prevent food from entering the nasal cavity?

A

soft palate and uvula

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23
Q

This structure traps and destroys pathogens entering the nasopharynx in air

A

pharyngeal tonsil

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24
Q

This structure drains the middle ear cavities and allows middle ear pressure to equalize with atmospheric pressure

A

Pharyngotympanic (auditory) tubes

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25
Q

True or False.

Both swallowed food and inhaled air pass through the nasopharynx

A

False

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26
Q

True or False.

In the oropharynx, both swallowed food and inhaled air pass through

A

True

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27
Q

Similarly to the oropharynx, this structure serves as a passageway for food and air and is lined with stratified squamous epithelium

A

Laryngopharynx

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28
Q

What two processes of respiration is the actual respiratory system responsible for?

A

Pulmonary ventilation and external respiration

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29
Q

What two processes of respiration is the circulatory system responsible for?

A

Transport of respiratory gases, internal respiration

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30
Q

Why is molecular oxygen so important in order to breathe?

A

Because oxygen is the final electron acceptor in the ETC of cellular respiration, which ends up making ATP

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31
Q

What is the site of gas exchange?

A

Respiratory zone

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32
Q

What are the structures of the respiratory zone?

A

respiratory bronchioles, alveolar ducts, and alveoli

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33
Q

Conduits to gas exchange sites

A

Conducting zone

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34
Q

The upper respiratory tract involves…

A

organs in the head and neck, nose through larynx

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35
Q

The lower respiratory tract involves…

A

organs of the thorax, trachea through lungs

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36
Q

Airflow in lungs goes from the bronchi to…

A

bronchi–> bronchioles–> alveoli

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37
Q

What is the voice box?

A

larynx

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38
Q

What constitutes the roof of the nasal cavity?

A

ethmoid and sphenoid bones

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39
Q

What constitutes the floor of the nasal cavity?

A

hard and soft palates

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40
Q

What are vibrissae and what do they do?

A

Hairs that filter coarse particles from inspired air

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41
Q

What type of epithelium tissue makes up the respiratory mucosa?

A

Pseudostratified ciliated columnar epithelium

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42
Q

What triggers sneezing?

A

Sensory nerve endings

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43
Q

What part of the respiratory mucosa moves contaminated mucus posteriorly to throat?

A

cilia

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44
Q

Inspired air is warmed by what part of the respiratory mucosa?

A

plexuses of capillaries and veins

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45
Q

What is the role of the nasal conchae during exhalation?

A

To reclaim heat and moisture

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46
Q

Passageway for food and air from the level of the soft palate to the epiglottis

A

Oropharynx

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47
Q

What is the opening to the oral cavity?

A

isthmus of the fauces

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48
Q

What is the smallest part of the pharynx?

A

oropharynx

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49
Q

This part of the pharynx extends to the larynx where it is also continuous with the esophagus

A

laryngopharynx

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50
Q

What are the 3 functions of the larynx?

A

1) provides a patent airway
2) routes air and food into proper channels
3) voice production

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51
Q

Splitting point where there is a diversion to esophagus and trachea

A

Larynx

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52
Q

What covers the laryngeal inlet during swallowing?

A

Epiglottis

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53
Q

How do the intrinsic muscles control vocal cords?

A

They pull on the cartilages and cause them to pivot

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54
Q

Are the vestibular folds true or false vocal cords?

A

False

55
Q

Are the false vocal cords superior or inferior?

A

Superior

56
Q

What is the role of the vestibular folds?

A

helps to close the glottis during swallowing

57
Q

Explain valsalva’s maneuver?

A

The glottis closes to prevent exhalation while the abdominal muscles contract and pressure rises. It is used to help empty the rectum or stabilize the trunk during heavy lifting

58
Q

What are the three layers that make up the trachea?

A

mucosa, submucosa, adventitia

59
Q

What layer of the trachea is outermost and made up of connective tissue that encases 16-20 C-shaped rings of hyaline cartilage?

A

adventitia

60
Q

Where does the trachealis muscle connect?

A

posterior parts of cartilage ring

61
Q

What is the carina?

A

Point where trachea branches into two bronchi

62
Q

What propels mucus upward?

A

Cilia

63
Q

What type of cell secretes mucus?

A

Goblet cell

64
Q

The branching pattern of the bronchi is called the…

A

bronchial respiratory tree

65
Q

The right main bronchus is…

A

wider, shorter, and more vertical than the left

66
Q

What does the main bronchus branch into?

A

Lobar bronchi (three for the right, two for left)

67
Q

Is there cartilage found in bronchioles?

A

No

68
Q

As bronchi turns into bronchioles, structural changes occur and one of these is that cartilage rings give way to…

A

Plates

69
Q

The respiratory zone is defined by…

A

the presence of alveoli

70
Q

When does the respiratory zone begin?

A

As the terminal bronchioles feed into respiratory bronchioles

71
Q

What accounts for most of the lungs volume?

A

Alveoli

72
Q

What structure is found within alveoli that allows for gas exchange?

A

Capillaries

73
Q

Histamine is a…

A

Bronchoconstrictor

74
Q

What is the function of alveoli pores?

A

They connect adjacent alveoli and allow air pressure throughout the lung to be equalized

75
Q

Alveolar walls are made up of a single layer of…

A

Type 1 epithelial cells

76
Q

What do alveolar walls allow for?

A

gas exchange by simple diffusion

77
Q

What do the alveolar walls secrete?

A

angiotensin converting enzyme (ACE)

78
Q

What type of cell secretes surfactant?

A

Type II epithelial cells

79
Q

What is the function of surfactant?

A

Keeps alveoli inflated so they don’t collapse

80
Q

Describe the left lung and how it differs from the right.

A

The left lung is smaller, separated into two lobes by an oblique fissure

81
Q

Describe the right lung and how it differs from the left.

A

The right lung has three lobes separated by oblique and horizontal fissures

82
Q

What are the three functions of the pleura and pleural fluid?

A

1) reduction of friction
2) creation of pressure gradients
3) compartmentalization

83
Q

Pulmonary circulation has _____ pressure and ______ volume while systemic circulation has ______ pressure and _____ volume

A

low, high, high, low

84
Q

What provides oxygenated blood to the actual lung tissue?

A

bronchial arteries

85
Q

Bronchial arteries supply all lung tissue except…

A

the alveoli

86
Q

True or False.

In order to breathe in and out, there must be pressure differences

A

True

87
Q

According to Boyle’s law, as pressure increases, volume…

A

Decreases

88
Q

According to Charle’s law, as temperature increases, volume….

A

increases

89
Q

Dalton’s law states that…

A

The total pressure of a gas mixture is equal to the sum of the partial pressures of it’s individual gases

90
Q

What is atmospheric pressure?

A

Pressure exerted by the air surrounding the body; 760 mmHg

91
Q

What is negative respiratory pressure?

A

Less than Patm

92
Q

What is positive respiratory pressure?

A

Greater than Patm

93
Q

What is intrapulmonary pressure?

A

Pressure in the alveoli that fluctuates with breathing

94
Q

True or False.

Intrapulmonary pressure always eventually equalizes with Patm

A

True

95
Q

What is intrapleural pressure?

A

Pressure in the alveoli that fluctuates with breathing

96
Q

Which one, intrapulmonary or intrapleural pressure is always negative?

A

Intrapleural; Pip

97
Q

What are the two things that cause negative intrapleural pressure?

A

Elastic recoil of lungs and surface tension of alveolar fluid

98
Q

What is transpulmonary pressure?

A

Intrapulmonary pressure - intrapleural pressure

99
Q

The greater the transpulmonary pressure, the _____ the lungs

A

larger

100
Q

Atelectasis is…

A

lung collapse

101
Q

What is the goal of gas flow?

A

To equalize pressure

102
Q

What happens to intrapulmonary pressure during inspiration?

A

Drops to -1 mmHg

103
Q

What five muscles contribute to inspiration?

A

sternocleidomastoid, scalenes, external intercostals, diaphragm, pectoralis minor

104
Q

What happens to intrapulmonary pressure during quiet expiration?

A

Rises to +1 mmHg

105
Q

What is the difference between quiet and forced expiration?

A

Quiet expiration is normally a passive process and forced expiration if an active process that uses abdominal and internal intercostal muscles

106
Q

Inspiratory muscles must overcome what three factors that hinder air passage and pulmonary ventilation?

A

Airway resistance, alveolar surface tension, and lung compliance

107
Q

What is the major nonelastic source of resistance to gas flow?

A

friction

108
Q

With increased resistance, gas flow ________

A

decreases

109
Q

Where does resistance to flow disappear?

A

At the terminal bronchioles where diffusion drives gas movement

110
Q

What dilates bronchioles and decreases air resistance?

A

Epinephrine

111
Q

What is surface tension in relation to alveoli?

A

Liquid molecules are attracted to one another at the gas-liquid interface of alveoli and they resist any force that tends to increase the surface area of the liquid

112
Q

What does surfactant do?

A

Reduces surface tension of alveolar fluid and discourages alveolar collapse

113
Q

What does the liquid coating of alveoli tend to do?

A

Reduce the alveoli to the smallest possible size

114
Q

How does surfactant reduce surface tension?

A

It disrupts hydrogen bonding by becoming interspersed between H20 molecules

115
Q

A measure of the change in lung volume that occurs with a given change in transpulmonary pressure

A

Lung compliance

116
Q

Distensibility (stretching) of lung tissue and alveolar surface tension create what situation?

A

High lung compliance

117
Q

Name the values for the partial pressures:

Inspired air
Po2:
Pco2:

A

Po2: 159
Pco2:0.3

118
Q

Name the values for the partial pressures:

Alveolar air
Po2:
Pco2:

A

Po2: 104
Pco2:40

119
Q

Name the values for the partial pressures:

Oxygenated blood
Po2:
Pco2:

A

Po2: 95
Pco2: 40

120
Q

Name the values for the partial pressures:

Tissue fluid
Po2:
Pco2:

A

Po2: 40
Pco2: 46

121
Q

Name the values for the partial pressures:

Deoxygenated blood
Po2:
Pco2:

A

Po2: 40
Pco2: 46

122
Q

Name the values for the partial pressures:

Expired air
Po2:
Pco2:

A

Po2: 116
Pco2: 32

123
Q

The central chemoreceptors monitor…

A

CO2

124
Q

The peripheral chemoreceptors in the aortic and carotid bodies monitor…

A

O2

125
Q

The depth and rate of breathing is controlled by…

A

The central chemoreceptors

126
Q

Ventilation increase is controlled by…

A

The peripheral chemoreceptors

127
Q

Where are peripheral chemoreceptors located?

A

Carotid and aortic bodies

128
Q

Where are central chemoreceptors located?

A

Surface of medulla

129
Q

What stimulates the central chemoreceptors?

A

H+

130
Q

Usually due to inadequate pulmonary gas exchange

A

hypoxemic hypoxia

131
Q

Inadequate circulation

A

Ischemic hypoxia

132
Q

Metabolic poison (cyanide)

A

Histotoxic hypoxia

133
Q

The primary effect of hypoxia is what?

A

Tissue necrosis