Ch12: Pharmacology Flashcards
what is pharmacodynamics?
the effect a drug has on the body
what is an agonist?
a medication that stimulates the receptors
what is an antagonist?
a medication that inhibits a receptor
what does the ‘action’ of a medication mean?
the therapeutic effect of the medication on the body
what is pharmacokinetics?
the processes that the body performs on a medication from absorption, distribution to elimination
what are the pharmacokinetic factors of a drug?
PEDO HAHAHA
Peak = the point when maximal clinical effects of a drug is achieved
Elimination = how the body breaks down and gets rid of medications
Duration = how long is the clinical effect
Onset of action = the time between administration and desired effect
what is the therapeutic effect of a drug?
the desired or intended effect of a medication on the body
what are unintended (adverse) effects?
effects that are undesirable but pose little/no risk
what are adverse effects?
any actions of a medication other than the intended action
what are untoward (adverse) effects?
effects that can be harmful to the patient
what do “contraindications” mean in the context of pharmacology?
reaons or conditions for which a medication should NOT be given to a patient
what are contraindications for nitroglycerin?
severe hypotension
erectile dysfunction medication was taken within 24h (it also dilates blood vessels)
if blood pressure is below 100mmHg = NO NEED
what is a contraindication for taking aspirin?
suspected head bleed
recent internal bleeding e.g. stomach ulcers (contact medical control)
what is a relative contraindication of epinephrine?
glaucoma
what do “indications” mean in the context of pharmacology?
reasons or conditions for which a medication is given
what are the indications for aspirin?
heart attack
pain or fever (rmb medicinal chem!)
what are is the indication for nitroglycerin?
angina (chest pain caused by reduced flow of blood to the heart). nitroglycerin relaxes blood vessel walls, allowing more blood flow (which is why severe hypotension is a contraindication)
what is the indication for diphenhydramine (Benadryl)?
allergic reaction
what is the intended effect of diphenhydramine (Benadryl)
blocks action of histamine in an allergic reaction
what are two unintended effects of diphenhydramine (Benadryl)?
1) dry mouth
2) drowsiness