Ch11 - Animal Procurement & Quarantine Flashcards
Which federal mandate provided descriptions of shipping crate sizes and configurations for hamsters?
Animal Welfare Regulations
What method of animal identification do most institutions use for animals arriving at a facility?
Cage cards
What species of laboratory animal does NOT have specific identification requirements based on their USDA number?
Horses
What approval is needed before ordering animals?
An approved IACUC protocol
What type of air pressure is maintained in a quarantine room?
Negative (air flows in, preventing inside contaminants from flowing out)
What is a sign of heat stress in rodents?
Excessive salivation
What is the microbiological status of animals that carry an unknown, and uncontrolled variety and number of organisms?
Conventional
What source of animals is MOST likely to harbor disease-causing agents?
A dealer who provides wild caught animals
What are 3 steps that a technician should do to verify and begin processing the contents of a new shipment of animals?
- assess and document that cleanliness of the transporting vehicle
- compare the original animal order with the shipping label info
- report container damage to the supervisor and transportation company
What is the class of dealer who breeds their own animals for sale to research facilities?
Class A dealer
What class of dealer obtains animals from random sources, conditions them, and sells them to research facilities?
Class B dealer
Name 3 work practices that can be used to minimize the risk of transmitting disease between animals in quarantine and those in established clean colonies.
- do this room last (after clean rooms)
- dispose of PPE after exiting room
- work done by trained staff
List 4 items of general information about the animals that should be provided on an animal procurement form.
Age, sex, species, strain or stock
What term refers to the types of organisms that an animal is carrying?
Microbial status
What is the term for the separation of newly received rodents from those already in the facility until the microbial status of the newly received animals has been determined? What type of pressure is this room under?
Quarantine; negative
Animal housing for which the primary goal is keeping an experimental infectious agents restricted within the population is called _________.
Containment
Why do health documents from the vendor accompanying an animal shipment NOT exempt the animals from quarantine?
The animals may have been exposed to infectious agents while in transit
If an animal is exposed to a pathogen while in transit to a research facility, typically how long is it before the animal will test positive for the pathogen?
2-3 weeks
What is the microbial status of lab animals that harbor no detectable bacteria, viruses or other microorganisms; also known as axenic.
Germfree
What is the microbial status of lab animals that are nearly devoid of microorganisms but have been provided with a small number of known bacteria?
Gnotobiotic or defined flora
What is the microbial status of lab animals that are carefully monitored to be sure they do not harbor certain pathogenic organisms?
Specific pathogen-free
Most animals need an acclimation and conditioning time period of _______, however NHPs need _______.
72 hours; 14 days
A period during which newly received animals that are underweight or in poor health are treated to improve their health and body condition is called ______.
Conditioning period
The time for animals to recover from transport and to adjust to new surroundings is called ________.
acclimation period
List 3 things that determine the period of time needed for an animal’s acclimation and conditioning period upon arrival.
- the species
- mode of transportation
- intended use
List 2 documents the technician should compare to confirm that the animals are received are the ones ordered.
purchase orders and shipping invoices
What documents typically contain the species or strain of the animal, the investigator’s name, protocol number, contact info, the source of the animal, and may contain a barcode?
Cage cards
What procedure should an animal technician perform before disposing of animal shipping containers?
Double check the containers for any remaining animals
The Animal Welfare Regulations specify the standards under which covered animals may be transported (ex: it specifies some characteristics of the materials with which shipping cages, boxes or cartons may be made). List 3 other topics covered in the transportation-related regulations of the AWR
Acceptable temp ranges, ventilation, and space;
sufficient room to make normal postural movements;
how often animals should receive food and water during shipment;
how often animals should be observed
Describe why wild caught animals should be housed away from the rest of the animals in the facility.
Wild caught animals have an unknown health status, and they are more likely to carry parasites and pathogens than animals purchased from a dealer
