Ch 8 Flashcards
A 28-year-old man was seen by a neurologist because he had experienced prolonged episodes of tingling and numbness in his right arm. He underwent a neurologic exam to evaluate his sensory nervous system. Which of the following receptors is correctly paired with the type of stimulus to which it is most apt to respond?
A. Pacinian corpuscle and motion. B. Meissner corpuscle and deep pressure. C. Merkel cells and warmth. D. Ruffini corpuscles and sustained pressure. E. Muscle spindle and tension.
D. Ruffini corpuscles and sustained pressure.
Nociceptors
A. are activated by strong pressure, severe cold, severe heat, and chemicals.
B. are absent in visceral organs.
C. are specialized structures located in the skin and joints.
D. are innervated by group II a erents.
E. are involved in acute but not chronic pain.
A. are activated by strong pressure, severe cold, severe heat, and chemicals.
A generator potential
A. always leads to an action potential.
B. increases in amplitude as a more intense stimulus is applied.
C. is an all-or-none phenomenon.
D. is unchanged when a given stimulus is applied repeatedly
over time.
E. All of the above.
B. increases in amplitude as a more intense stimulus is applied.
Sensory systems code for the following attributes of a stimulus:
A. modality, location, intensity, and duration.
B. threshold, receptive eld, adaptation, and discrimination.
C. touch, taste, hearing, and smell.
D. threshold, laterality, sensation, and duration.
E. sensitization, discrimination, energy, and projection.
A. modality, location, intensity, and duration.
Which of the following are correctly paired?
A. Neuropathic pain and withdrawal re ex B. First pain and dull, intense, di use, and unpleasant feeling C. Physiologic pain and allodynia D. Second pain and C fibers E. Nociceptive pain and nerve damage
D. Second pain and C fibers
A 32-year-old woman experienced the sudden onset of a severe cramping pain in the abdominal region. She also became nauseated. Visceral pain
A. shows relatively rapid adaptation.
B. is mediated by B fibers in the dorsal roots of the spinal
nerves.
C. is poorly localized.
D. resembles “fast pain” produced by noxious stimulation of
the skin.
E. causes relaxation of nearby skeletal muscles.
C. is poorly localized.
A ventrolateral cordotomy is performed that produces relief of pain in the right leg. It is effective because it interrupts the
A. left dorsal column.
B. left ventrolateral spinothalamic tract.
C. right ventrolateral spinothalamic tract.
D. right medial lemniscal pathway.
E. a direct projection to the primary somatosensory cortex.
B. left ventrolateral spinothalamic tract.
Which of the following CNS regions is not correctly paired with a neurotransmitter or a chemical involved in pain modulation?
A. Periaqueductal gray matter and morphine
B. Nucleus raphe magnus and norepinephrine
C. Spinal dorsal horn and enkephalin
D. Dorsal root ganglion and opioids
E. Spinal dorsal horn and serotonin
C. Spinal dorsal horn and enkephalin
A 47-year-old woman experienced migraine headaches that were not relieved by her current pain medications. Her doctor prescribed one of the newer analgesic agents that exert their e ects by targeting synaptic transmission in nociception and peripheral sensory transduction. Which of the following drugs is correctly paired with the type of receptor it acts on to exert its antinociceptive effects?
A. Topiramate and Na+ channel B. Ziconotide and NMDA receptors C. Naloxone and opioid receptors D. Lidocaine and TRPVI channels E. Gabapentin and Nav1.8
A. Topiramate and Na+ channel
A 40-year-old man loses his right hand in a farm accident. Four years later, he has episodes of severe pain in the missing hand (phantom limb pain). A detailed PET scan study of his cerebral cortex might be expected to show
A. expansion of the right hand area in his right primary somatosensory cortex.
B. expansion of the right hand area in his le primary somatosensory cortex.
C. a metabolically inactive spot where his hand area in his le primary somatosensory cortex would normally be.
D. projection of bers from neighboring sensory areas into the right hand area of his right primary somatosensory cortex.
E. projection of fibers from neighboring sensory areas into the right hand area of his left primary somatosensory cortex.
E. projection of fibers from neighboring sensory areas into the right hand area of his left primary somatosensory cortex.
A 50-year-old woman undergoes a neurologic exam that indicates loss of pain and temperature sensitivity, vibratory sense, and proprioception in the le leg. ese symptoms could be explained by
A. a tumor on the right medial lemniscal pathway in the sacral spinal cord.
B. a peripheral neuropathy.
C. a tumor on the le medial lemniscal pathway in the sacral
spinal cord.
D. a tumor affecting the right posterior paracentral gyrus.
E. a large tumor in the right lumbar ventrolateral spinal cord.
D. a tumor affecting the right posterior paracentral gyrus.
