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Patho Test 1 Evolve/Elsevier > Ch. 7 Adaptive Immunity > Flashcards

Ch. 7 Adaptive Immunity Flashcards

1
Q 
Which of the following best describes foreign or nonself substances?
  Immunoglobulins
  Lymphocytes
  Antibodies
  Antigens
A

Antigens

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2
Q

Which of the following is a TRUE statement regarding the immune response in humans?
Before birth there is no production of lymphocytes.
B lymphocytes come from the thymus.
The thymus releases mature lymphocytes.
Generation of clonal diversity occurs in primary lymphoid organs.

A

Generation of clonal diversity occurs in primary lymphoid organs

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3
Q

Which of the following is a description of the cells and their functions in the humoral arm of the immune system?
Cells undergo differentiation and develop into subpopulations.
Cells attack cancerous cells.
Antibodies are primarily responsible for protection.
Is also called cellular immunity.

A

Antibodies are primarily responsible for protection

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4
Q 
Which of the following terms describes the type of immunity that occurs when preformed antibodies are transferred from donor to recipient?
  Passive immunity
  Active immunity
  Memory immunity
  Cellular immunity
A

Passive immunity

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5
Q 
Which of the following best describes the precise portion of the antigen that is configured for recognition and binding of an antibody?
  Paratope
  Epitope
  Self-antigen
  Immunogen
A

Epitope

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6
Q 
Which of the following is NOT a criterion that influences the degree of immunogenicity?
  Foreignness to the host
  Appropriate size
  Appropriate quantity
  Simple chemical complexity
A

Simple chemical complexity

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7
Q 
Which of the following best describes an antigen that is too small to initiate an immune response?
  Carrier
  Allergen
  Hapten 
  Self-antigen
A

Hapten

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8
Q 
Which of the following is NOT one of the five molecular classes of immunoglobulins?
  IgG
  IgN 
  IgM
  IgE
A

IgN

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9
Q

9.ID: 37598660
Which of the following is TRUE regarding IgA antibodies?
IgA-2 is predominantly found in blood.
IgA-1 is predominantly found in the body’s secretions.
The J chain anchors together the IgA molecules.
The gamma heavy chain is predominant.

A

The J chain anchors together the IgA molecules

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10
Q

Which of the following is the function of the cytotoxic T lymphocyte?
Activation of macrophages
Direct stimulation of B-cell maturation
Isotype switching
Direct killing of foreign and abnormal cells

A

Direct killing of foreign and abnormal cells

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11
Q 
Which of the following best describes inactivation or blocking of the binding of the antigen to the receptor?
  Agglutination
  Precipitation
  Neutralization
  Attenuation
A

Neutralization

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12
Q

Which of the following is a correct description of IgE?
It is designed to protect the host from large viruses.
It is the primary cause of common allergies.
This is the only inflammatory cell that can damage a virus.
It is designed specifically to prevent the invasion and attachment of pathogens through mucous membranes.

A

It is the primary cause of common allergies

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13
Q

Which of the following is accurate in describing the humoral response?
The B-cell population can respond to only a certain number of antigens.
B cells become activated on recognition of an antigen.
Clonal diversity is generated by the foreignness of the antigen.
Immunoglobulins are composed of six polypeptide changes.

A

B cells become activated on recognition of an antigen

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14
Q

Which of the following is a TRUE statement regarding fetal and neonatal immune function?
The primary immune system is adequate.
The secondary immune system is adequate.
The immune response does not fully develop until 6 years of age.
Maternal antibodies are catabolized fully by 10 weeks of age.

A

The secondary immune system is adequate

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15
Q

Which of the following is a TRUE statement regarding aging and the immune system function?
Older adults have decreased circulating antibodies.
T-cell function is increased.
B-cell production is inferior.
Response to infection is more rapid.

A

B-cell production is inferior

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16
Q 
Which is NOT a true statement regarding central tolerance?
  Autoreactive T cells are allowed to leave the thymus.
  Autoreactive T cells are deleted in the thymus.
  Double-positive T cells that react with MHC class I or class II are deleted.
  Immature T cells that have a TCR that binds self-antigens are deleted.
A

Autoreactive T cells are allowed to leave the thymus

17
Q 
Which T cell types regulate the overactivation of the immune response?
  Th cells
  Treg cells
  Memory T cells
  Cytotoxic T cells
A

Treg cells

Patho Test 1 Evolve/Elsevier (19 decks)

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