Ch 20 Meds For Depressive Disorders Flashcards

1
Q

Name TCA meds

A
Imipramine 
Doxepin
Nortriptyline
Amoxapine
Trimipramine
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2
Q

What are uses for TCAs

A
Depressive disorders
Neuropathic pain
Fibromyalgia 
Anxiety disorders
Insomnia
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3
Q

What are side effects of TCAS

A
Orthostatic hypotension
Anticholinergic effects
Sedation
Decreased seizure threshold
Diaphoresis
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4
Q

TCAs should be used cautiously in who

A

Ppl with coronary artery disease
Diabetes, liver, kidney, and respiratory disorders, urinary retention and obstruction, angle closure glaucoma
Benign prostatic hypertrophy and hyperthyroidism

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5
Q

What are med/ food interactions of TCAs

A

Concurrent use of MAOI can cause hypertensive crisis
The use of antihistamines can cause additive anticholinergic effects
Direct and indirect acting sympathomimetics
Alcohol, benzodiazepines, opioids,

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6
Q

Name SSRI DRUGS

A
Citalopram
Escitalopram 
Paroxetine
Sertraline 
Vilazodone
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7
Q

What are the therapeutic uses of SSRIs

A

Major depression
OCD, bulimia, premenstrual dysphoric disorders
Panic disorders
PTSD

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8
Q

WHAT ARE side effects of SSRIs

A
Sexual dysfunction
CNS stimulation
Wt loss followed by wt gain
Serotonin syndrome
Withdrawal syndrome, hyponatremia, Bruxism
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9
Q

What class of drugs treat depression

A

TCAs
SSRIs
MAOIs
Atypical antidepressants

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10
Q

What are med interactions of SSRIs

A

MAOI, TCA, St. John’s wort increase risk of serotonin syndrome
Coumadin levels will increase if taken concurrently
Lithium
NSAIDS anticoagulants can further suppress platelet aggregation

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11
Q

Name MAOIs

A

Isocarboxazid
Tranylcypromine
Selegiline ( transdermal patch

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12
Q

What are the therapeutic uses of MAOIs

A

Depression

Bulimia

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13
Q

What are side effects of MAOIs

A

CNS stimulation
Orthostatic hypotension
Hypertensive crisis from ingesting tyramine containing foods
Rash with transdermal patch

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14
Q

MAOIs are contraindicated in who

A

Ppl taking SSRIs or TCAs,those with pheochromocytoma, HF,cardiovascular and cerebral vascular disease and or severe renal insufficiency, diabetes or seizure disorder

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15
Q

What is selegiline and what are its contraindications

A

MAOI ( transdermal patch )

Contraindicated in ppl taking carbamazepine or oxcarbazepine because it will increase the levels of the MAOI

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16
Q

Name atypical antidepressants

A

Bupropion

17
Q

What is the therapeutic intent of atypical antidepressants such as bupropion

A

Treats depression
Alternative to SSRIs
Aid to quit smoking
Prevention of seasonal pattern depression

18
Q

What are side effects of atypical antidepressant

A

Headache, dry mouth, GI DISTRESS,constipation
Tachycardia, nausea, restlessness, wt loss, suppression of appetite
Seizures at higher dose ranges

19
Q

Bupropion is contraindicated in who

A

Ppl with seizure disorder
Concurrent use of MAOIs
Anorexia or bulimia because bupropion suppresses the appetite

20
Q

What are med interactions of the atypical antidepressant bupropion

A

Concurrent use of MAOIs may increase risk for toxicity discontinue MAOIs 2 weeks before beginning treatment of bupropion

21
Q

Name other atypical antidepressant drugs

A
Venlafaxine 
Duloxetine 
Desvenlafaxine
Mirtazapine
Reboxetine
Trazadone
22
Q

What are nursing administrations for TCAs

A

Monitor for cardiac dysrhythmia said which are an indication of toxicity
Administer at bedtime because of sedation effects

23
Q

What is nursing administration for SSRIs

A

Take in am to minimize sleep disturbances
Take with food to mimimize GI distress
Monitor sodium levels in older adults taking diuretics

24
Q

For clients with seasonal pattern depression when should they begin taking bupropion

A

In the autumn and gradually taper dose and discontinue by spring

25
Q

Priapism is a side effect of what drug

A

Trazadone which is a atypical antidepressant

26
Q

What is nursing education for trazadone

A

Take at bedtime