Ch. 15: Schizophrenia & Psychotic Disorders Flashcards
Intro: schizophrenia is probably caused by a combination of factors, including:
- Genetic predisposition
- Biochemical dysfunction
- Physiological factors
- Psychosocial stress
- We still don’t know the exact cause. More predisposed for it if you have a parent with it. Definitely dysfunctional neurotransmitters. Early onset of drug use can cause more mental illness.
treatment for schizophrenia needs to be…
- comprehensive and presented in a multidisciplinary effort
- There is a sense of loss for people who have schizophrenia. We need to treat with de-stigmatization
- 1/3 of people with schizophrenia die from suicide
- High ongoing SI is common
Of all mental illnesses, schizophrenia probably causes more…
- Lengthy hospitalizations
- Chaos in family life
- Exorbitant costs to people and governments
- Fears
- Majority of people dx w/ it will be dx by age 25
Nature of schizophrenia. It can cause disturbances in:
- Thought processes
- Perception (often paranoid delusions)
- Affect (often blunted)
- there is a severe deterioration of social and occupational functioning
- In the U.S. the lifetime prevalence of schizophrenia is about 1%
- Psychosis: a break from reality
- Sometimes a loss of abstract thinking
4 phases of schizophrenia: phase 1
- Premorbid phase
- Could be seen as a normal part of puberty or middle school
- Social maladjustment, antagonistic thoughts and behavior, shy and withdrawn
- poor peer relationships
- Doing poorly in school
- Antisocial behavior
4 phases of schizophrenia: Phase 2
- Prodromal phase
- A distinct change
- lasts from a few weeks to a few years
- Deterioration in role functioning and social withdrawal
- substancial functional impairment
- Sleep disturbance, anxiety, irritability
- Depressed mood, poor concentration, fatigue
- Perceptual abnormalities, ideas of reference, and suspiciousness herald onset of psychosis
4 phases of schizophrenia: Phase 3
- Schizophrenia
- Acute psychosis. many have hallucinations.
- If one gets tx on first break, then prognosis is better overall
- In the active phase of the disorder, psychotic symptoms are prominent –>
- Delusions
- Hallucinations
- Impairment in work, social relations, and self-care
4 phases of schizophrenia: Phase 4
- Residual phase
- symptoms similar to those of the prodromal phase
- Flat affect and impairment in role functioning are prominent
- One becomes more impaired with the more episodes of psychosis they have
- Meds and other tx’s help
- Talk dismissal to voices can help
- Pts often go off meds
Prognosis of schizophrenia
- A return to full premorbid functioning is not common
- Better is later onset
- More positive prognosis if there is no family history
- And if they are female
Biological Predisposing factors for schizophrenia
- Biological influences: genetics play an important role in dev. of schizophrenia.
- Biochemical influences: one theory suggests that schizophrenia may be caused by an excess of dopamine activity in the brain. Abnormalities in other neurotransmitters have also been suggested.
Other bio Predisposing factors for schizophrenia
- Factors that have been implicated:
- Viral infection
- Anatomical abnormalities
- Electrophysiology
- Epilepsy
- Huntingtons disease
- Birth trauma, head injury in adulthood, alc. abuse, cerebral tumor, cerebrovascular accident, Lupus
Psyc. Predisposing factors for schizophrenia
- These theories no longer hold credibility. Researchers now focus their studies of schizophrenia as a brain disorder.
- Psychosocial theories probably developed early on out of a lack of info related to a bio connection
Environment Predisposing factors for schizophrenia
- Sociocultural factors: poverty has been linked with the development of schizophrenia
- Downward drift hypothesis: Poor social conditions seen as consequence of, rather than a cause of, schizophrenia
more environment Predisposing factors for schizophrenia
- Stressful life events may be associated with exacerbation of schizophrenic symptoms and increased rates of relapse
- Studies of genetic vulnerability for schizophrenia have linked certain genes to increased risk for psychosis and particularly for adolescents who use cannabinoids
Theoretical integration for schizophrenia
- It is likely a biologically based disease, the onset of which is influenced by factors in the internal or external environment
Side note: complication of clozapine
can cause agranulocytosis which one can die from. Rare. A very very effective drug otherwise that can save peoples lives.
Schizophrenia and marijuana use
marijuana can cause schizophrenia in 1/10 people who are predisposed to it. Can be after one use, or chronic use.
Types of schizophrenia: Delusional disorder
- Must be at least one month of 1 of the following (remember this criteria)
- The existence of prominent, nonbizarre delusions
- Erotomanic type (someone like a celebrity is in love with them)
- grandiose type, Jealous, persecutory
- Somatic type or mixed type