Ch 15

Question 1

What is the most common mode of transmission with the G.I. tract?

Answer 1

Contaminated food and water

Question 2

What is a Parenteral route?

Answer 2

Go through the skin and into the dermis, such as a bite, stab, needle puncture, scrapes, etc.

Question 3

LD50

Answer 3

Lethal Dose
Toxin production, not the infection
Most potent toxins as the lowest LD50
More exact

Question 4

Units for LD50?

Answer 4

Nanogram (ng) or milligram(mg) over kilogram (kg)

Question 5

ID50

Answer 5

Infectious Dose

Using animal models, how many microbes did it take to get half of that population sick with the disease

Question 6

Capsule:

What merges with the phagosome?

Answer 6

Lysosome, and end up with phagolysosome

Question 7

If you’re a bacteria and produce Coagulase, what advantage would that be?

Answer 7

You can surround with the clot, live within the clot so that the defense can’t get you

Question 8

What’s the advantage of kinase?

Answer 8

• Have access to the bloodstream to spread to new tissues and organs
• Cam go systemic and relocate around the body

Question 9

Where are ferritin proteins made?

Answer 9

The liver

Question 10

What do siderophores do?

Answer 10

Bind free iron in the blood

Fe^2+ and Fe^3+

Question 11

Why do siderophores want to bring the iron into the cell?

Answer 11

Iron is an important cofactor for bacterial enzymes so they need it so their enzymes can function properly

Question 12

Ruffling

Answer 12

Where the bacteria alter the apical surface of the cell as they’re entering. They are changing the entire shape of the cell at the area that they’re using for entry and once they get inside to so they can secrete enzymes and kill the cell

Question 13

What do you T cells do?

Answer 13

They secrete a variety of toxic compounds

Question 14

What do the compounds of the T cells do?

Answer 14

They induce inflammation and they damage host cells