Ch 13: Supplements Flashcards
Most Common Supplement
Multivitamin and Mineral formula
Hierarchy of Fitness: highest/Foundational priority
- Daily energy needs according to the client’s goal and demands of the activity
Hierarchy of Fitness: #2 priority
- Meeting daily protein requirements for the desired outcomes
Hierarchy of Fitness: #3 priority
- Tailoring carbohydrate and fat amounts and timing based on client preferences and energy needs for training and competition
Hierarchy of Fitness: #4 priority
Meeting micronutrient needs based on nutritional gaps in the diet
Hierarchy of Fitness: #5 priority
Proper supplementation to support body composition, training, and performance
Something that improves either physical or mental performance.
Ergogenic Aid
Nutrition Coach Prevention with Supplements
Nutrition Coaches can prevent wasteful spending, adverse health effects, inadvertent doping, and subsequent suspensions from athletic competition, all while gaining the benefits certain dietary supplements have to support fitness, exercise, and athletic performance goals.
Current standards of practice set forth by the U.S. Food and Drug Manufacturers for dietary supplement manufacturers.
Current Good Manufacturing Practices (cGMP)
FDA performs random inspections to ensure cGMP
In US, what regulates Supplements
Dietary Supplement and Health and Education Act (DSHEA) of 1994 (U.S. Food and Drug Administration, 2018)
Under the DSHEA, what are herbs, botanicals, vitamins, minerals and other ingredients are regulated by what?
Food
Do not have to be approved by FTC or FDA
What are manufacturers obligated to do?
- Ensure supplements are made properly
- Make accurate label claims
- Prohibited from marketing supplements to prevent, treat, cure, or diagnose a disease
Most common infractions of cGMP
Lack of processes for verifying the identity of raw ingredients and assessing purity, identity, and composition of finished products. This lack of compliance to cGMPs by supplement manufacturers results in poor product quality, including ineffective formulas and contamination with hidden ingredients.
FDA recall of supplements
Serious or sufficient adverse events are reported or new, unapproved ingredients are discovered
- The FDA maintains an online database of over 900 supplements that have been found to be contaminated with prescription drugs and illegal substances
Evidence-based approach to dietary supplements
- Evaluating whether a supplement is safe and effective based on the strength of the research and the population studied;
- Potency of the formula, including the dosages and ingredient forms
- Whether the ingredients are legal
- Whether the finished product has undergone independent testing for accuracy of label claims and absence of contaminants and banned substances.
Credible Sources for Supplements
National Institute of Health’s Office of Dietary Supplements, the Micronutrient Information Center of the Linus Pauling Institute, and other reputable organizations such as the Academy of Dietetics and Nutrition and the International Olympic Committee
Elements of a well-designed clinical trial include the following
Human subjects
Control groups
Randomization of the supplement(s) and placebo
Measurement of relevant outcomes
Control of confounding variables
Creatine monohydrate has been shown to elevate muscular creatine stores when consumed
3 to 5 grams a day over approximately 4 weeks
Major companies in the United States that provide certification to verify the content of their supplements
Consumer Lab
U.S. Pharmacopeia (USP)
Informed Choice
Banned Substances Control Group (BSCG)
NSF International
Consumer Lab’s quality evaluation
Requires that products from consumer channels be randomly tested once a year. Approval indicates the product was tested for ingredient identity, strength (amounts stated on the label), purity (free of specified contaminants), and disintegration
USP’s Dietary Supplement Verification Program
Ensures the product contains the ingredients and amounts listed on the label, is free from harmful levels of specified contaminants (e.g., pesticides, heavy metals, or microbes), is made in a facility that is compliant to cGMPs, and will breakdown in the body within a specified time. Products are also tested annually to retain the USP Verified mark
BSCG’s Certified Drug-Free program, Informed Choice’s Registration Process, and NSF International’s Certified for Sport program.
- Testing for ingredient identity and strength, testing for hidden drugs and banned substances in sports is also conducted to varying degrees and standards
- These programs may include random audits of manufacturing facilities and procedures (cGMPs) and random testing of finished products. On successful completion of the certification process, products are permitted to include the certifier’s logo and are listed on the certifier’s website.
NSF International
Offers a Certification for Sport program that includes testing for banned substances listed by various sports organizations. Major League Baseball, the National Hockey League, and the Canadian Football League require members to utilize only NSF Certified-for-Sport products.
Guidelines for Selecting Dietary Supplements
- Verify the ingredients are supported with solid evidence for efficacy and safety from scientific reviews, reputable organizations, and/or well-designed human studies.
- Determine whether ingredient forms and dosages in product formulas match evidence-based recommendations.
- Check if the product is independently tested to verify label accuracy. For athletes, third-party testing for banned substances is critical.
- Request independent research from companies that verifies the claims for their products.
2015–2020 DGA report identified key nutrients that are under-consumed
Vitamins A, C, D, E, Choline, Potassium, Magnesium, Iron, calcium and fiber
Abbreviation for docosahexaenoic acid, essential omega-3 fatty acid found in marine sources such as fish and krill, highly abundant in the human brain, eyes, and sperm cells.
DHA
Abbreviation for eicosapentaenoic acid, essential omega-3 fatty acid found in marine sources such as fish and krill, serves as a precursor to various compounds that have anti-inflammatory activities in the body in addition to serving as structural components of the brain and eye tissue.
EPA
What should a Multivitamin contain?
Vitamins A, C, D, E, K, B1, B2, B3 B6, B12, Folic Acid, Calcium, Iron, Magnesium, Zinc, Copper, Selenium, Chromium and Potassium
Strong Evidence Muscle-Gain Supplements
Protein
Creatine monohydrate
Essential amino acids
Moderate/Mixed Evidence Muscle-Gain Supplements
BCAAs
HMB
Phosphatidic acid
Weak/Lack of Evidence Muscle-Gain Supplements
Arginine
Glutamine
ATP
Alpha-ketoglutarate
Prohormones
Synthesized endogenously in the liver and kidneys from amino acids and is stored primarily in muscle tissue. Its role is to regenerate intracellular ATP stores via the phosphocreatine system during high-intensity activity
Creatine Monohydrate
Dietary Sources of Creatine monohydrate
Beef, poultry, and seafood
Supplementation with Creatine Monohydrate
- Effectiveness at increasing muscular stores and enhancing muscle mass in conjunction with resistance training
-Greater gains in muscle tissue seem to be a result of superior training adaptations due to increased workload capacity at high intensities. - Individuals who supplement with creatine monohydrate for 1 to 3 months have been shown to gain 1 to 2 more kilograms of mass
Side effects of Creatine Monohydrate
Weight Gain due to water retention and muscle mass increase
Loading phase of Creatine Monohydrate
(With maintenance phase can increase muscular creatine stores by 20 to 40%)
5 - 7 days of consuming 20 to 25 grams daily, or about 0.3 gram/kilogram of body weight in doses split throughout the day
Maintenance phase of Creatine Monohydrate
Consuming a daily dose of 3 to 10 grams daily, with the higher-maintenance dose likely more appropriate for individuals with greater muscle mass
Increases Creatine monohydrate uptake and muscular retention
Co-ingestion of Carbohydrates (with or without protein)
Duration of Creatine Supplementation
The duration of creatine supplementation is dependent on the individual’s desired outcome, length of high-intensity training phase, and time restrictions due to competitive events.
Normalization of Creatine Stores
On cessation of use, creatine stores normalize within 4 to 8 weeks