CH 12 Flashcards
Principles of Pharmacology
Pharmacodynamics
a process by which medication works on the body
Agonist
Causes stimulation of receptors
Antagonist
binds to a receptor and blocks other medications or chemicals
Dose
amount of medication given. Every medication has it’s own dosing.
Action
The therapeutic effect that a medication is expected to have on the body
Pharmacokinetics
Actions of the body upon the medication or chemical: onset of action, duration, elimination, peak
Factors affecting how a medication works
Route of administration
Shock States - if you don’t have blood flow, something moving through the blood doesn’t work.
Indications
Reasons or conditionsCon
Adverse effects
enteral medications
enter the body through the digestive system
Parenteral medications
enter the body through some means other than the digestive track.
PO, PR
by mouth. “Per Os” latin for by mouth. PR is by rectum
IV
intravenous
Transcutaneous
(transdermal): through the skin
Intraosseous
Capsules
filled shell; filled with liquid or powder
Solution
mixture that will not separate
Suspension
Will separate. Often drunk.
Topical medications
Lotions, creams, ointments
Transcutaneous medications
Designed to be absorbed through the skin.
the “rights” of medication administration
Right patient. Right medication and indication. Right dose. Right route. Right time. Right education. Right to refuse. Right response and evaluation. Right documentation.
Oral Glucose
Treats hypoglycemia. Do not give to unconscious patients
Aspirin
Reduces fever, pain, and inflammation.
Inhibits platelet aggregation: makes platelets become slippery. Useful during heart attack.
Contraindications: hypersensitivity to aspirin, liver damage, bleeding disorder, asthma. Never give to children.
Sublingual medications
Advantages: easy to advice patients, quick absorption.
Disadvantages: ?
Example: Nitroglycerin
Nitroglycerin
Epinephrine
Increases heart rate and constricts blood vessels. Do not give to patients with hypertension, hypothermia. . .
Naloxone (Narcan)
Used to reverse the effects of an opioid overdose