Ch 11 and 12 Flashcards
Mendel’s Model for Inheritance
variation in characteristics are from multiple versions of genes, an offspring inherits one allele from each parent per trait, dominant allele determines phenotype
Law of Segregation
each gamete gets only one allele
true breeding
homozygous dominant or recessive parents
test crossing
hybridization by crossing two true breds
monhybrid cross
cross of two heterozygous individuals for one trait
dihybrid cross
cross of two heterozygous individuals for two traits
law of independent assortment
when crossing two traits, they are entirely independent, creating 16 genotypes instead of still just 4
complete dominance
one allele determines the phenotype
incomplete dominance
combination of alleles creates an inbetween phenotype (red + white = pink)
codominance
combination of alleles creates a mix of phenotype (red + white = spotted colors)
epistasis
a double trait relationship in which the second trait alters the state of the first
polygenic inheritance
a trait combination that is on a spectrum of phenotypes (skin color)
multiple alleles
one trait has more than one possible allele (blood type has three)
pleiotropy
a single allele combination that determines multiple characteristics
chromosome theory of inheritance
the way we knew how inheritance worked: 1. chromosomes and genes are both paired with diploid. 2. alleles separate during meiosis. 3. fertilization restores pairs
Morgan’s experiments: why the fly?
used fruit fly, creates hundreds of offspring in one mating, new generation can occur in two weeks, only 4 chromosomes
Morgan’s experiments: sex-linked
discovered flies with red and white eyes and the ratios of males and females, more males had mutation, X-linked traits
Sex-determining region of Y (SRY)
a region that must be present to convert ovaries to testes on the Y chromosome
X-linked genes
have both sex related and non-sex related traits
hemizygous
because Y has no allele, the X has only one allele for males so it cant be homo or hetero, its hemi
X inactivation
most of one female X chromosome is inactivated during pregnancy because don’t need double genes
linked genes
genes located near each other tend to be inherited together
Morgan’s experiment: linked genes
black body and small wings or gray body and normal wings; when parental frequency is more than 1/2 is it linked
recombination of linked genes
when offspring have different phenotypes than parents, close genes evidently did cross-over; often creates entirely new genes
linkage map
shows distance and recombination frequency on genes
Chi-square test
observed and expected frequency value showing that the frequency differences are due to chance OR due to a genetic pattern; based on df and p=0.05
nondisjunction
chromosome separation goes wrong; one gamete has two, one has three
aneuploidy
monosomic = 2n-1; trisomic = 2n+1
polyploidy
created by trisomic aneuploidy on every chromosome so that the organism is 3n
chromosomal deletion
fragment of chromosome deleted
chromosomal duplication
fragment added to a chromosome as an exact copy
chromosomal inversion
reversed segment within a chromosome
translocation
moves a chromosome’s section to a nonhomologous chromosome