CF + bronchiectasis Flashcards
1
Q
what is bronchiectasis
A
abnormal and permanently dilated
2
Q
what is the main cause of bronchiectasis
A
infection (viral and bacterial)
immunodeficiency
asthma
3
Q
risk factors for bronchiectasis
A
immunosuppressive therapy
rheumatoid arthritis
CF
4
Q
what is the characteristic pathology of bronchiectasis
A
dilated and thickened bronchi
5
Q
what is the characteristic symptom of bronchiectasis
A
cough with large amounts of sputum
6
Q
what symptoms are associated with bronchiectasis
A
clubbing
SOB
coarse crackles
Haemoptysis
7
Q
what is CF
A
alteration of the viscosity and the tenacity of mucus
8
Q
what is the genetics of CF
A
autosomal recessive, 1 in 25 people have it
9
Q
what gene is associated with CF
A
CFTR gene
10
Q
what is the diagnosis of CF
A
high sodium sweat testing (1st line)
molecular testing
