Cerebrovascular Disease Flashcards

1
Q

Hemorrhage accounts for what percent of stroke?

A

10%

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2
Q

What is the stroke mortality at 1 month? 1 year? 3 years? 7 years?

A

19%, 23%, 46%, 60%

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3
Q

What is the angiogram risk of stroke in the general population? In patient’s with atherosclerosis?

A

1-3%

up to 5%

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4
Q

How common do seizures occur in cortical embolic strokes?

A

20%

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5
Q

What is the risk of stroke following TIA? What is the risk of MI?

A

10% at 3 months, 26% over 2 years

21% over 5 years

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6
Q

When is the highest stroke risk following TIA?

A

first 48 hours

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7
Q

What is the risk of ICH with tPA?

A

6%

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8
Q

Endovascular clot retrieval, angioplasty, or intra-arterial tPA may be performed up to ________ after onset of stroke deficit.

A

4.5 to 6 hours

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9
Q

Decompressive hemicraniectomy in stroke has been show to _______ and ________.

A

decrease ICP, increase survival

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10
Q

Why are thrombotic strokes generally slower onset than embolic strokes?

A

more time for collaterals to form in thrombotic strokes

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11
Q

tPA can be given to patients when stroke deficit symptoms onset within _______.

A

3 hours

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12
Q

What histologic finding is seen with lacunar strokes?

A

lipohyalin degeneration of small vessels (lipohyalinosis)

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13
Q

What were the conclusions of the NASCET trial?

A

North American Symptomatic Endarterectomy Trial

  • CEA in symptomatic patients w/ >70% stenosis
  • reduces stroke risk from 26% to 9% over 2 years
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14
Q

What were the conclusions of the ACAS trial?

A

Asymptomatic Carotid Atherosclerosis Study

  • CEA in asymptomatic patients w/ >60% stenosis
  • reduces stroke risk from 11% to 5% over 5 years
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15
Q

Stroke of the anterior choroidal artery territory results in what sympotmology?

A

Contralateral hemiplegia, hemianesthesia, and homonymous hemianopsia

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16
Q

What is Weber’s syndrome?

A

midbrain stroke syndrome from occlusion of interpeduncular branches to the midbrain

ipsilateral CN III palsy w/ contralateral hemiplegia

17
Q

Occlusion of what posterior circulation artery can cause horner’s syndrome?

A

AICA

18
Q

Ventral pontine syndrome is caused by occlusion of what vessel?

A

basilar artery brances (circumfrential/paramedian arteries)

19
Q

What’s another name for ventral pontine syndrome?

A

Millard-Gubler syndrome

20
Q

What are the symptoms in Ventral pontine syndrome?

A

Ipsilateral facial weakness
Contralateral hemiplegia
Horizontal diplopia

21
Q

What is another name for lateral pontine syndrome?

A

Marie-Foix syndrome

22
Q

What vessel is occluded in lateral pontine syndrome?

A

basilar artery circumferential brance or AICA

23
Q

What are the symptoms in lateral pontine syndrome?

A

Contralateral hemiplegia
Contralateral decreased pain and temperature
Ipsilateral ataxia

24
Q

What is another name for medial medullary syndrome?

A

Dejerine’s syndrome

25
Q

What vessel is occluded in medial medullary syndrome?

A

Vertebral artery

26
Q

What are the symptoms in medial medullary syndrome?

A

Contralateral hemiplegia
Contralateral impaired posterior column function
Ipsilateral tongue weakness

27
Q

What is another name for lateral medullary syndrome?

A

Wallengberg’s syndrome

28
Q

What vessel is occluded in lateral medullary syndrome?

A

PICA

29
Q

What are the symptoms in lateral medullary syndrome?

A

Decreased contralateral pain and temperature
Ipsilateral Horner’s syndrome
Ipsilateral decreased facial pain and temperature
(descending fibers and spinal nucleus of V)
Nystagmus
Nausea
Vertigo (vestibular nuclei), Decreased gag
Hoarseness
Dysphagia
Cord paralysis (IX and X)
Decreased taste (solitary tract)
Ipsilateral falling
Ataxia (restiform body)
Hiccups