Cerebellum

Question 1

Climbing fibers enter via the ________ and mossy fibers enter via the _______.

Answer 1

inferior cerebellar peduncle

middle cerebellar peduncle

Question 2

What is the main function of the flocculonodular lobe?

Answer 2

vestibular function (inputs from vestibular apparatus and nuclei)

Question 3

What is the main function/input of the anterior lobe of the cerebellum?

Answer 3

posture, muscle tone, processing information from muscle tendons

input from spinocerebellar tracts

Question 4

What does the anterior lobe of the cerebellum arise from?

Answer 4

dorsal nucleus of Clarke

Question 5

The output of the vermis is via the __________.

Answer 5

fastigial nucleus

Question 6

Output of the intermediate zone is via ______.

Answer 6

globose and emboliform nuclei

Question 7

Output of the latera zone is via ________.

Answer 7

dentate nucleus

Question 8

Anterior lobe of the cerebellum degeneration occurs from _______ or _______.

Answer 8

ethanol and malnutrition

Question 9

What is titubation? If present, where is the pathology?

Answer 9

3 Hz anterior/posterior head bob

cerebellar

Question 10

What causes slurred speech?

Answer 10

corticobulbar tract interruption

Question 11

What is the inheritance pattern of Friedrich’s ataxia?

Answer 11

AR

Question 12

What is the genetic cause of Friedrich’s ataxia?

Answer 12

GAA repeat on Frataxin gene on Ch 9

Question 13

Pathologically what occurs in Friedrich’s ataxia?

Answer 13

Demyelination of posterior columns, corticospinal, ventral, and lateral spinocerebellar tracts, leading to gait ataxia and clumsiness