Central Nervous System Flashcards
What does the nervous system do?
It is the “hard wire” control for the body
2 divisions of nervous system
CNS
PNS
What makes up CNS
Brain and spinal cord
What is PNS?
Nerves that extend out
2 parts of PNS
1) Afferent
2) Efferent
What is Afferent?
Sensory (flows up)
What is Efferent?
Carries out command (down)
2 parts of Efferent
1) Somatic
2) Autonomic
What is somatosensory?
Division of afferent that we feel consciously (pain, smell, equilibrium)
What is visceral stimuli?
Afferent; involuntary sensation that controls things like blood pressure
-gets info from sympathetic/parasympathetic
Somatic nervous system
Part of efferent; motor neurons that go to skeletal muscle and under our control.
Autonomic
Part of efferent; controls visceral function (involuntary)
2 parts of autonomic
Sympathetic
Parasympathetic
What is a sympathetic responses
Fight/Flight
What is a parasympathetic response?
Rest/Relax
What 3 body parts does sympathetic/parasympathetic control?
1) Smooth muscle
2) cardiac muscle
3) glands
What is Ramon y Cajal responsible for?
Golgi staining to see neuronal cells
Another name for cell body of a neuron
Soma
What is in cell body?
Nucleus and organelles
What are dendrites of nerve cell?
Extensions from cell body (dendritic trees)
What do dendrites do?
Provide input to nerve cell
What is axon hillock?
Where action potential begins after stimulation
What is axon?
Tail of nerve cell
What is the end point of the axon called?
Axon terminal
Where does one cell communicate to another cell?
From axon terminals to dendrites
What is insulation of axon called?
Myelination
What helps to speed up and preserve electrical signal along an axon?
Myelin sheath
What is myelin sheath in PNS called?
Schwan cells
Spaces between myelination?
Nodes of Ranvier
What is myelination of CNS called?
Oligodendrocytes
What is another name for oligodendrocytes?
Glial cells
How do oligodendrocytes myelinate?
With foot-like projections that wrap around the axon
What is a neuronal cell that connects Afferent and Efferent neurons?
Interneuron
What is difference in voltage across a membrane called?
Membrane potential
What is the charge of ECF?
Positive
What is charge of ICF?
Negative
What is resting membrane potential for a cell?
-70mV
What is the major ion of ECF?
Na+
What are major components in ICF?
K+
Amino Acids and proteins (negatively charged)
What is a separation or difference in charge called?
Potential
What is the separation of charge across the membrane called?
Membrane potential
If chemical and electrical are equal in size and pointed in opposite directions (equilibrium reached), what is that called?
Equilibrium potential
What are 2 types of tissue where membrane potential will change dramatically?
Muscle and nerves
Why do muscle and nerve cells change?
Because they are excitable cells
What is a major fluctuation in membrane potential called?
Action potential
What charge is the threshold potential?
-50mV
What does -50mV trigger the opening of in the membrane?
Voltage gated Na+ channels
What causes repolarization/hyper polarization of the cell after action potential is maxed?
Leaking of K+ from the cell
What are the protections to the CNS?
1) skull and meninges
2) CSF
3) blood brain barrier
What are tough connective tissues that protect the brain?
Meninges
What are the 3 meninges?
1) dura
2) arachnoid
3) pia mater
Which meninge has blood vessels?
Arachnoid
Where is CSF formed?
Choroid plexus
How much CSF is there?
125-150ml
What is the difference of CSF compared to blood?
Lower K+
Lower protein
Higher Na+
Cells of CNS have what resting membrane potential?
-85mV
Cells of the body have action potential more easily than the cells of the brain and spinal cord, t/f?
True
What would happen if cells of the brain and spinal cord were excited too easily?
Seizures
What is the highly selective network of cells and capillaries that protects the brain from substances crossing?
Blood brain barrier
What is the primary energy source of the CNS?
Oxygen and glucose
What do astrocytes and ependymal cells do in BBB?
Prevent substances from entering
How is glucose transferred through the BBB from plasma to IF?
Insulin independent membrane transporters
What are basic functions of the brain?
Regulate Homeostasis
Emotion
Movement
Senses
Memory
Cognition
Which matter has cell bodies, synapses, dendrites, neuroglia?
Gray matter
What matter has myelinated axon fibers?
White matter
What is CNS gray matter called?
Nucleus
What is gray matter of PNS called?
Ganglion
What lobe deals with vision
Occipital
What lobe for hearing?
Temporal
What lobe for motor?
Frontal
What part in frontal lobe controls voluntary movement?
Primary motor cortex
What part in frontal lobe controls learned/planned movement (tie shoes)?
Pre-motor cortex
What part in frontal lobe controls sequenced movement (dance)?
Supplementary motor area
What lobe deals with body sensations?
Parietal
Primary somatosenory cortex senses body sensations, t/f?
True
Somatosensory association area (behind primary) senses what?
Texture, shape
What part of frontal lobe deals with emotion and social integration?
Prefrontal cortex
What doesn’t fully develop until adulthood?
Prefrontal cortex
In what hemisphere are language areas?
Left
What part of left frontal lobe is responsible for muscles involved in speech?
Broca’s area
What area in left temporal lobe is AV processing and comprehension?
Wernicke’s area
What is responsible for fine tuning of motor, sensory and emotional input/output
Basal nuclei (aka basal ganglia)
Where is basal nuclei?
Deep in cerebrum (gray matter)
What part of the brain is involved in balance, movement planning and execution?
Cerebellum
What is the function of the cerebellum?
Subconscious motor coordination
What part of the brain is affected in Parkinson’s?
Basal nuclei
What part of the brain is affected if there are constant tremors?
Cerebellum
What is sensory filter?
Thalamus
What controls homeostasis and endocrine system?
Hypothalamus
What regulates body temperature?
Hypothalamus
What regulates water balance and thirst?
Hypothalamus
What is our emotional response system?
Limbic system
3 parts of brain stem
Midbrain
Pons
Medula
Where is the Reticular Activating System (RAS)?
Midbrain
What does RAS do?
Filters sensory input, attention, arousal of cerebral cortex
What does midbrain control?
Superior = visual
Inferior = hearing
What does Pons control?
Breathing rhythm
What do pyramids of medulla contain?
Motor fibers
What do medulla olives do?
Relay info to cerebrum and cerebellum
What do autonomic nuclei of medulla control?
Heart rate
BP
Breathing
Vomiting, coughing…
Dorsal spinal cord
Afferent
Ventral spinal cord
Efferent
How many pairs of spinal nerves?
31
What is a specific surface region of the body innervate by a spinal nerve?
Dermatome
How many pairs of cranial nerves?
12
Cranial nerves connect directly to the
Brain
What is a sensory pathway that goes up to the brain?
Afferent
What is a motor response to a stimulus?
Efferent
What is a simple, involuntary pathway from spinal cord?
Reflex