Central Nervous System Flashcards
Cannons Postulates (4)
- Nervous regulation of internal environment
- Tonic control
- Antagonistic control
- One chemical signal can have different effects in different tissues
CNS
Brain and spinal cord
PNS
All nerves connecting to the CNS, cranial and spinal nerves
Gray matter
Unmyelinated nerve cells
White matter
Myelinated axons, few cell bodies
Cranium
Bony skull that encases the brain
Vertebral column
Bone where spinal cord runs through
Meninges
Membrane between bone and tissues
Types of meninges
Dura mater, arachnoid membrane, pia mater
Purpose of meninges
Cushion and protect delicate neural tissue
Order the layers of the meninges from inside to outside
Pia mater (most inner) –> arachnoid mater –> dura mater (most external)
Spinal nerve roots
Dorsal and ventral
Dorsal spinal nerve root
Sensory
Ventral spinal nerve root
Motor
Dorsal root gray horn
Process sensory information
Ventral root gray horn
Send out motor information
Ascending vs. descending tracts
Ascending= carry signals to brain
Descending= carry signals from brain
Spinal reflex
Initiates a response without input from the brain (ex. pulling hand away from something hot)
Spinal cord serves as an….
Integrating center
SEQ process of reflexes
Sensory receptor produces a sensory potential in response to stimulus –> sensory neuron conducts action potentials –> processed by brain or spinal cord gray matter –> action potential from integrating center travels to motor neuron –> effector (reflex)
Blood-brain barrier
Protects the brain from harmful substances, HIGHLY selective permeability –> mediated by astrocyte foot processes and tight junctions
Astrocyte foot processes
Secrete paracrines that promote tight junction formation
Tight junctions
Prevent solute movement between endothelial cells –> keep blood-brain barrier highly selective
Cerebral spinal fluid
Clear and colorless, protects brain from chemical and physical injury, circulates through various openings in the brain and subarachnoid space
What produces the cerebrospinal fluid?
Choroid plexus
Choroid plexus
At the center of the brain, produces cerebrospinal fluid
Subarachnoid space
Provides a layer of cushioning for the brain
Metabolic requirements of the brain
Oxygen, glucose
Brain is responsible for what percentage of glucose consumption?
50%
What passes freely across blood-brain barrier?
Oxygen, brain requires high oxygen
What percentage of oxygenated blood pumped by heart does brain recieve?
15%
Frontal lobe
Primary motor cortex, motor association area, responsible for skeletal muscle movement
Parietal lobe
Primary somatosensory cortex, sensory association area
Occipital lobe
Visual association area, visual cortex
Temporal lobe
Auditory cortex, auditory association area
Olfactory cortex
Smell
Gustatory cortex
Taste
Brain association areas
Integrate information from sensory and motor areas, direct voluntary behaviors