Central Motor System 1 Flashcards

1
Q

Motor Cortex

A

Controls volitional movement

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2
Q

Premotor Cortex

A

-Involved in the planning of actions
-Stimulation can cause complex movements (e.g. reaching)
-Sends most connections to the primary motor cortex
-Sends some connections directly to the spinal cord

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3
Q

Mirror Neurons

A

These neurons fire…
-when an action is performed
-when watching someone perform that same action

-Found in premotor cortex and somatosensory cortex
-Some argue that mirror neurons are key to speech perception
-Acoustics of speech are directly tied to the physical motion of the articulators
-Accurately perceiving speech may require using the percieved sound to determine the (unseen) articulator movement
–Motor theory of speech perception

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4
Q

Primary Motor Cortex

A

-Involved in generating actions
-Stimulation can cause simple movements
-Receives input from somatosensory cortex
-An area that controls muscles in one area often receives proprioceptive input from that same area

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5
Q

Cortical respresentation

A

-Motor functions are organized topographically
-The size of the cortical area for a body part is related to the precision of motor control
-Is plastic and experience-based

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6
Q

Motor Programs

A

-When you write your name in vastly different sizes, you are using different muscle groups
-Then end result looks the same but scaled
-The speed and acceleration of the hand movement is also scaled
-This is called motor equivalence
-This suggests planning occurs at an abstract level
-This also explains how we can deal with perturbations and other unexpected sensory information

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7
Q

Basal Ganglia

A

-Involved in the refinement of motor activities
–Compresses competing motor activity
–Regulates desired motor activity
–Contributes to learned complex movements (like speech)

-Signals pass from the motor cortex through the basal ganglia and back to the motor cortex

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8
Q

Nucleus Accumbens

A

-Central structure for reward
-Involved in addiction

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9
Q

Substantia nigra

A

-Major source of dopaminergic neurons

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10
Q

Dopamine

A

-Critical for reward/addiction
-Degeneration of these neurons lead to Parkinson’s disease

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11
Q

GABA

A

-Major inhibitory neurotransmitter
-Plays a central role in the inhibitory pathways for the basal ganglia

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12
Q

Major Loops

A

-The basal ganglia is a part of a number of major loops where signals are modified
-These loops refine motor actions
-The basal ganglia does not initiate motor action, it only modifies it

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13
Q

Complex motor learning

A

-Learning complex motor skills (like talking) requires basal ganglia involvement
-For learned complex motor skills the basal ganglia plays a regulating role

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14
Q

Direct Pathway

A

Excitatory (Inhibit inhibition)

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15
Q

Indirect Pathway

A

Inhibitory (inhibit inhibition of inhibition)

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16
Q

Parkinson’s disease

A

-Reduction of dopaminergic neurons in substantia nigra
-Characterized by:
–Resting tremors
–Slow movements (bradykinesia)
–Shuffling gait
–Difficulty initiating movements

-Substanita nigra inhibits the indirect pathway (inhibits an inhibitory pathway –> excitatory)

Substantia nigra excites the direct pathway ( excites and excitatory pathway –> excitatory)

17
Q

Reducing the neurons on the substantia nigra would result in..

A

Less movements in both pathways

18
Q

Parkinson’s Treatments

A

-L-Dopa
-Direct deep brain stimulation