Cellular Differentiation Flashcards
1
Q
Stem Cell
A
an unspecialized cell that can divide without limit as needed and can under specific conditions, differentiate into specialized cells
- divided into lots of categories according to potential to differentiate.
- they can also continually divide and regenerate new stem cells instead of specializing
2
Q
Totipotent
A
- first embryonic cells that arise from the division of the zygote are the ultimate stem cells
- have potential to differentiate into any of the cells needed to enable and organism to grow and develop
- specialized into pluripotent
3
Q
pluripotent
A
- embryonic cells that develop from totipotent stem cells and are precursors to fundamental tissue layers of the embryo
- has potential to differentiate into any type of human tissue but can’t support full development of organism
- specialized into multipotent
4
Q
multipotent stem cell
A
- potential to differntiate into types of cells within a give cell lineage (like RBC or WBCs)
- specialized into oligopotent
5
Q
oligopotent
A
- limited to becoming one a few different cell types
- specialized into unipotent
6
Q
unipotent
A
- fully specialized and can only reproduce to generate more of its own specific cell type
7
Q
what happens when a cell differentiates (becomes more specialized?)
A
- undertakes major changes in size, shape, metabolic activity and overall function
- to differentiate into specialized form, it needs to manipulate genes and proteins that are expressed
8
Q
transcription factor
A
one of a class of proteins that bind to specific genes on DNA molecule and either promote or inhibit transcription
- used by cell to differentiate