Cellular Control - 6 Flashcards

1
Q

What is the reason that a brain cell differs from a muscle cell?

A

Different proteins are being made due to the activation and deactivation of different genes.

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2
Q

What happens to activated genes within a cell?

A

They are transcribed into mRNA, which is then translated into protein.

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3
Q

What is the process called that modifies a cell and leads to its specialization?

A

Differentiation.

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4
Q

What is a transcription factor (TF)?

A

Proteins that activate or deactivate genes.

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5
Q

What are the two types of transcription factors?

A
  • Activators
  • Repressors
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6
Q

What role do activators play in gene expression?

A

They bind to the promoter region and help RNA polymerase to bind and transcribe the gene.

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7
Q

What do repressors do in the context of gene expression?

A

They bind to the gene and block RNA polymerase from binding.

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8
Q

What is an operon?

A

A section of DNA that contains a cluster of genes controlled by a single promoter.

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9
Q

What are the components of an operon?

A
  • Structural genes
  • Control elements
  • Regulatory gene
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10
Q

What is the function of the lac repressor in E. coli?

A

It binds to the operator region, blocking RNA polymerase from binding to the promoter region when lactose is absent.

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11
Q

What occurs when lactose is present in E. coli?

A

Lactose binds to the repressor, changing its shape and allowing RNA polymerase to transcribe the structural genes.

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12
Q

What does the lacZ gene code for?

A

An enzyme called beta-galactosidase.

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13
Q

What is splicing?

A

The process of removing introns from mRNA before translation.

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14
Q

In which type of organisms does splicing occur?

A

Eukaryotes.

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15
Q

What is cAMP?

A

A second messenger molecule that activates proteins by changing their 3D structure.

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16
Q

What role do Hox genes play in an organism?

A

They control the general organization of the organism’s body plan.

17
Q

What is the importance of Hox genes in evolution?

A

They are highly conserved, indicating their crucial role in development.

18
Q

What is apoptosis?

A

Controlled cell death where cells annihilate themselves without making a mess.

19
Q

What is the function of mitosis in body plan development?

A

To create enough cells to fill the body.

20
Q

What are the two types of stimuli that can activate apoptosis?

A
  • Internal stimuli (e.g., DNA damage)
  • External stimuli (e.g., pathogenic infection)
21
Q

What is a mutation?

A

Any change to the base sequence of DNA.

22
Q

What are the types of mutations?

A
  • Substitution
  • Insertion
  • Deletion
  • Inversion
23
Q

What is a frameshift mutation?

A

A mutation that changes the codon and all following codons due to insertion or deletion.

24
Q

What can lead to a neutral effect of a mutation on a protein’s function?

A

The mutation changes a base but the amino acid remains the same due to the degeneracy of the genetic code.

25
Q

How can a mutation be beneficial or harmful?

A

It can produce a protein with an altered tertiary structure affecting the organism’s function.