Cell Membrane - 2 Flashcards
1
Q
Roles of the membrane
A
- Partially permeable barriers
- Sites of chemical reactions
- Sites of cell communication within and between cells
- Compartmentalisation
- Provide the structure of organelles
2
Q
What is a phospholipid
A
- Has a hydrophilic head, made of a glycerol with a phosphate group attached
- Hydrophobic tail made of fatty acids
3
Q
Define the term Hydrophilic
A
- Uneven charges/polar
- Easily interact with water
4
Q
Define the term Hydrophobic
A
- Evenly distributed charges
- Repels water molecules
5
Q
Define the term Amphipathic
A
Some parts charged and some not
6
Q
Components of cells membranes
A
- Phospholipids
- Channel proteins
- Glycolipids
- Glycoproteins
- Cholesterol
- Extrinsic proteins
7
Q
What are Integral proteins
A
- Are carrier molecules or channels
- Help transport ions, sugars and amino acids across the membrane
- Some are receptors for hormones and enzymes
8
Q
What are Peripheral proteins
A
- Free on the membrane surface or bound to integral proteins
- May act as receptors
- Many are glycoproteins
9
Q
What are Glycoproteins and Glycolipids
A
- Act as a receptor sites
- can assist in binding cells together
- Glycoproteins = carbohydrate + protein
- Glycolipids = carbohydrate + phospholipids
10
Q
What is Cholesterol
A
- Lipid with a molecular formula C27H470
- controls membrane fluidity and permeability
- More cholesterol the less fluid and less permeable
11
Q
Which Factors affect permeability of the memebrane
A
- Solvents
- Temperature
- Detergents
12
Q
How do Solvents affect permeability
A
- Dissolve the lipids in the membrane
13
Q
How does Temperature affect permeability
A
- Negative temperatures cause ice crystals to form and pierce the membrane, increasing permeability
- High temperatures increase the kinetic energy and phospholipids move further apart. Proteins denature and fall out leaving large gaps
14
Q
What is Cell signalling
A
- How cells communicate with other cells
- need messenger/ signal molecules
- Needs receptors on cell surface
15
Q
Define Diffusion
A
- The movement of molecules from a region of higher concentration to a region of lower concentration down a concentration gradient
- Passive process