Cell Membrane - 2 Flashcards

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1
Q

Roles of the membrane

A
  • Partially permeable barriers
  • Sites of chemical reactions
  • Sites of cell communication within and between cells
  • Compartmentalisation
  • Provide the structure of organelles
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2
Q

What is a phospholipid

A
  • Has a hydrophilic head, made of a glycerol with a phosphate group attached
  • Hydrophobic tail made of fatty acids
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3
Q

Define the term Hydrophilic

A
  • Uneven charges/polar
  • Easily interact with water
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4
Q

Define the term Hydrophobic

A
  • Evenly distributed charges
  • Repels water molecules
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5
Q

Define the term Amphipathic

A

Some parts charged and some not

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6
Q

Components of cells membranes

A
  • Phospholipids
  • Channel proteins
  • Glycolipids
  • Glycoproteins
  • Cholesterol
  • Extrinsic proteins
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7
Q

What are Integral proteins

A
  • Are carrier molecules or channels
  • Help transport ions, sugars and amino acids across the membrane
  • Some are receptors for hormones and enzymes
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8
Q

What are Peripheral proteins

A
  • Free on the membrane surface or bound to integral proteins
  • May act as receptors
  • Many are glycoproteins
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9
Q

What are Glycoproteins and Glycolipids

A
  • Act as a receptor sites
  • can assist in binding cells together
  • Glycoproteins = carbohydrate + protein
  • Glycolipids = carbohydrate + phospholipids
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10
Q

What is Cholesterol

A
  • Lipid with a molecular formula C27H470
  • controls membrane fluidity and permeability
  • More cholesterol the less fluid and less permeable
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11
Q

Which Factors affect permeability of the memebrane

A
  • Solvents
  • Temperature
  • Detergents
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12
Q

How do Solvents affect permeability

A
  • Dissolve the lipids in the membrane
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13
Q

How does Temperature affect permeability

A
  • Negative temperatures cause ice crystals to form and pierce the membrane, increasing permeability
  • High temperatures increase the kinetic energy and phospholipids move further apart. Proteins denature and fall out leaving large gaps
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14
Q

What is Cell signalling

A
  • How cells communicate with other cells
  • need messenger/ signal molecules
  • Needs receptors on cell surface
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15
Q

Define Diffusion

A
  • The movement of molecules from a region of higher concentration to a region of lower concentration down a concentration gradient
  • Passive process
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16
Q

What Factors affect diffusion

A
  • Temperature
  • Steepness of gradient
  • surface area
  • Nature of diffusing molecule
17
Q

Which Particles can diffuse

A
  • Lipid based molecules
  • Very small molecules
18
Q

Particles that cant diffuse

A
  • Large molecules
  • Charged particles
19
Q

What is Facilitated diffusion

A
  • Passive transport
  • Involves channel proteins or carrier proteins
  • Occurs down the concentration gradient
20
Q

Define Active transport

A

Uses energy in the form of ATP to move molecules or ions against a concentration gradient

21
Q

Define Bulk transport

A
  • Uses membranes to transport large amounts of materials
  • Needs ATP
  • Two types: Endocytosis (Entering) and exocytosis (Exiting)
22
Q

Define Osmosis

A

The movement of water molecules from a region of higher water potential to a region of lower water potential down a water potential gradient, across a partially permeable membrane

23
Q

What occurs in a Isotonic solution

A

No net movement

24
Q

What occurs in a Hypotonic solution

A
  • Water moves into the cell
  • Animal cell bursts (Lysis)
  • Haemolysis
  • Plant cell becomes turgid
  • Doesn’t burst due to cell wall
25
Q

What occurs in a Hypertonic

A
  • Water moves out the cell
  • animal cell shrinks
  • crenation
  • Plant cell becomes flaccid
  • Plasmolysis