Cells & Tissues Flashcards

1
Q

What is the bulk of the heart muscle made up of?

A

Myocardium

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2
Q

What is the inner surface of the myocardium made up of?

A

Endothelium

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3
Q

What does the right ventricle pump?

A

Deoxygenated blood to the lungs

Low pressure 25mmHg

Little resistance to blood flow

Short distance to the lungs

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4
Q

What does the left ventricle pump?

A

Oxygenated blood to all organs of the body

Higher pressure 120 mmHg

Thick muscular wall

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5
Q

Outline the valves of the heart;

A

• atrioventricular (bicuspid/mitral/tricuspid)

•semi lunar valves (aortic & pulmonary)

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6
Q

What are atrioventricular valves attached to?

A

Chordae tendinae

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7
Q

What is the tension of the chordae tendinae regulated by?

A

Papillary muscles

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8
Q

When ventricles contract what also contracts? And what does this cause?

A

Popularly muscles also contract

Tightens the chordae tendinae and prevents the valve cusps from everting into the atria

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9
Q

Give some characteristics of cardiac muscle;

A

Fibres arranged in a latticework

Fibres divide,recombine & spread

Striated appearance

Myofibrils contain actin & myosin

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10
Q

What are intercalated discs?

A

Cell membranes that separate individual cardiac muscle cells

At each disc cell membranes fuse together

Allow rapid diffusion of ions

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11
Q

What 2 syncytiums is the heart composed of?

A

Atrial syncytium - two walls of the area

Ventricular syncytium - two walls of the ventricle

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12
Q

What is the average for action potential?

A

105mV

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13
Q

What is the sequence of excitation?

A

Involves increase in cytosolic calcium

Contraction of atria & ventricles must be coordinated to prevent AV valves closing during ventricle filling

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14
Q

What are the action potential of the cardiac muscle fibres 3 phases?

A
  1. Rapid depolarisation - voltage gates Na+ channels open
  2. Plateau - voltage gates Ca2+ channels open
  3. Depolarisation - voltage gated K+ channels open, K+ outflow
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15
Q

Describe the P wave of the ECG;

A
  • SA node fires, atrial depolarisation
  • atrial systole
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16
Q

Describe the QRS complex of the ECG;

A
  • AV node fires, ventricular depolarisation
  • ventricular systole
17
Q

Describe the T wave of the ECG;

A

Ventricular repolarisation

18
Q

What’s the name for the heart initiating its own impulse?

A

myogenic

19
Q

What is the myogenic motion controlled by?

A

Controlled by cardiovascular centre located in ventrolateral medulla

20
Q

What 2 systems work to oppose each other?

A

SNS

PNS

21
Q

What is the function of SNS?

A

Accelerates hearts actions

Increase in rhythm

Force of contraction

Excitability increased

22
Q

What is the function of PNS?

A

decrease in chronotropic effect

Decelerates the hearts actions

Inotropic effect

23
Q

What is the function of endocrine hormones?

A

Released from the adrenal gland, adrenaline & dopamine are all involved in the initiation of the “fight or flight” response

24
Q

What is the function of endocrine hormones?

A

Released from the adrenal gland, adrenaline & dopamine are all involved in the initiation of the “fight or flight” response