Cells of the Nervous System Flashcards
Central nervous system components (2)
Brain
Spinal cord
Peripheral nervous system components (2)
Cranial nerves
Spinal nerves
About how many neurons in the human brain?
Over 86 billion
2 types of cells in nervous system
Neurons
Glia
Dendrite function
Receive signals
Soma function
Integrate signal
Axon function
Send signal
How many axon(s) does a neuron have?
1
Relatively speaking, how many dendrite(s) does a neuron have?
More than 1
Synapse
Point of contact between neurons
Post-synaptic: dendrite or axon?
Dendrite
Pre-synaptic: dendrite or axon?
Axon
Synaptic cleft
Space between axon and dendrite
Soma
Neuron cell body
Axon hillock
Site of action potential initiation
Golgi
Protein packaging and delivery
Endoplasmic reticulum: what is it, what is synthesized there
Processing center
Synthesized: proteins (rough), lipids (smooth)
Nucleus
Command center
DNA replication and transcription
Ribosomes
Protein synthesis
5 ways neurons are classified
Location Connections Morphology Functionality Gene expression
Projection neuron: definition and example
Neuron that has dendrites and cell body in one region, but axon projects to and synapses in another region (ex: motor neuron- cell body in spinal cord, synapses on muscle)
Efferent
Exiting from
Ex: motor neuron is efferent from spinal cord
Afferent
Going to
Ex: motor neuron is afferent to muscle
Interneurons
Receive and send signals in the same region
Example of interneuron
Inhibitory interneurons in spinal cord
Excitatory
Activates neuron it synapses on
Inhibitory
Reduces activity of neuron it synapses on
Can projection neurons and interneurons be excitatory, inhibitory, or both?
Both
Unipolar neuron
Soma with 1 neurite/process (has branches, but not well defined)
Pseudo-bipolar or pseudo-monopolar neuron
Axon has split into 2 branches: soma is attached at the side
Bipolar neuron
Soma with 2 extensions: 1 axon and 1 dendrite
Multipolar neuron
Most common type of neuron
1 axon, more than 1 dendrite
Which is more numerous, glia or neurons? How many times more of one than the other?
Glia: 10-50 times more than neurons
Glia functions (5): regulate ____ ____ around neuron, ____ and ____, _____ neuron ______, ___ neurons, recycle _____
Regulate chemical environment around neuron Repair and regeneration Support/stabilize neuron organization Feed neurons Recycle neurotransmitters
Function of myelination
Increase action potential conduction velocity
2 types of glial cells that are involved in myelination
Oligodendrocytes (CNS) Schwann cells (PNS)
2 types of glial cells that protect from infection and damage
Astrocytes
Microglia
What is the specific role of astrocytes?
Form blood-brain barrier
What is the specific role of microglia?
Scavenge dead cells
Tripartite synapse
Astroglia surround the synapse and play a role in synaptic function