Cells and Tissue of the Nervous system Flashcards

1
Q

What is the central nervous system and periphery nervous system composed of

A

CNS- Brain and spinal cord

PNS- cranial and spinal nerves

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2
Q

What is the divisions of the PNS

A

Sensory - afferent

Motor - efferent

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3
Q

What is the further division of Efferent PNS

A

Somatic - voluntary

Autonomic - involuntary (sympathetic/parasympathetic)

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4
Q

What is the two cell types found in the neurosytem

A

Neurons - excitable cells

Gilal cells - nonexcitable supporting cells

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5
Q

What is the features and structure of a typical neuron

A

Composed of multiple dendrites
cell body
One long axon
and a sympathetic terminal

With AP traveling from the cell dendrites to sympathetic terminals

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6
Q

What is the 3 different types of neurons

A

Multipolar
Bipolar
Pseudounipolar

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7
Q

What type of neurone is the most typical motor neurone

A

Mutipolar

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8
Q

What type of neurone is pseudo unipolar

A

Sensory neurone

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9
Q

What is the important about the structure of pseudo unipolar

A

Dendrite passes onto to axon directly as celll body sits outside central nervous system - ganglion

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10
Q

What kind of neurone is bipolar

A

specialized sensory neurons for the transmission of special senses
(smell, sight, taste, hearing and vestibular functions)

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11
Q

Were are bipolar neurons found

A

Olfactory mucosa

Retinal nerve fibres

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12
Q

What features of neurone allow it to have a high metabolic rate

A

Prominent Nucleus with loos chromatin

Mitochondria
rER
Golig apparatus

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13
Q

What is the cytoplasm in the cell body and axon called

A

Cell body - perikaryon

axon - axoplasm

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14
Q

What is features of neurones

A

Long living
Axon has the potential to grow bak
Amitotic - cant do mitosis (cell body damage is irreversible)

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15
Q

What is the purpose of the myelin sheath (the envelope around the axon

A

increases conduction speed in axons by saltory conduction

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16
Q

How does salutary conducting occur

A

AP jumps from node of raniver to next node

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17
Q

What is similarity and differences between myelinated and non myelinated axon

A

Both axons have schwann cells wrapped around

but in nonmyelinated axon still wrapped by schwann cells but myelin sheath is not formed

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18
Q

What produces myelin sheath

A

Schwann cells (PNS)

Oligodendrocytes (CNS)

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19
Q

What disease shows the clinical importance of myelin sheath

A

Multiple sclerosis

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20
Q

What occurs in multiple sclerosis and what is the affect of this

A

Patchy loss/scarring of myelin sheath = demyelination

meaning nerve conduction across affected axons is abnormal

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21
Q

What is a good investigation for multiple sclerosis

A

MRI as shows plaque with demyelination

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22
Q

What is the name of a myelinated axon

A

mesaxon

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23
Q

Why don’t pain and sensory follow the same path

A

As have different tracts

24
Q

Define tracts

A

bundles of axons carrying specific information within the white matter = fibre pathways

25
What forms the grey matter in the CNS
Cell bodies and non myelinated axons
26
What forms the white matter in the CNS - why is it white?
Myelinated axons white as myelin (from membrane lipids) colours the matter
27
What forms the myelinated axons and cell bodies in the periphery
nerves and ganglions
28
What is a collection of cell bodies called in the central nervous system
Nuclei
29
What is a collection of cell bodies outside the CNS called
Ganglion
30
What is the 4 glial cells found in the CNS
astrocyte oligodendrocyte Microglia ependymal
31
Function fo astrocyte
Covers the synapse and capillaries Forms blood brain barrier - help in K+ buffering
32
What is the function of microgilal
Phagocytees | scar tissue formation
33
What is the function of ependymal
Line ventricles
34
What is the two Glial cells found in the PNS
Satellite cells | Schwann cells
35
What is the function of satellite cells
Surround neuronal cell bodies
36
What is 4 big parts of the brain
cerebellum Cerebrum Diencephalon Brainstem
37
What is the three parts of the brain stem
mid brain pons medulla
38
Where does the cranial nerve comes from
Brain stem
39
What does the cavity inside the neural tube from in the development of the nervous system
Ventricles
40
How many ventricles are formed and what are they called
2 lateral ventricles 3rd ventricle Cerebral aqueduct 4th Ventricle
41
Where is the lateral ventricles found
Cavity in the cerebral hemisphere
42
Where is the third ventricle
Cavity in the diencephalon
43
What is the smallest ventricle and where is it located
The cerebral aqueduct | Found going down the middling e
44
Where is the fourth ventricle exactly located
In the hindbrain | between the cerebellum posteriorly and the pons/medulla anteriorly
45
As soon as the neural tube forms what does it divided into and then further divide into
3 primary vesicles and then 5 secondary vesicles
46
What is the 3 primary vesicles
Prosencephalon - Forebrain Mesencephalon - Midbrain Rhombencephalon - Hindbrain
47
What is the 5 secondary vesicles
Telencephalon - forebrain Diencephalon -forebrain Mesencephalon - midbrain Metencephalon -hindbrain Myelencephalon - hindbrain
48
What does the telencephalon in the forebrain develop into
The cerebral hemisphere
49
What does the diencephalon in the forebrain develop into
Thalamus and hypothalamus
50
What does the hindbrain | (Metencephalon + Myelencephalon) develop into
Pons and medulla | and the cerebellum at the back
51
What does the Mesencephalon develop into
the midbrain
52
Where is CSF found
Inside the ventricles Centre canal of spinal cord - between pia and arachnoid
53
Where is CSF formed
Fomred in the chord plexus in each ventricle | a thin vascular structure
54
What is the function of the CSF
Responsible for the maintenance of the intracranial pressure
55
What is the circulation of the CSF
Circulates ventricles then leave ventricular space between thin layer at the roof of the 4th ventricle Via 3 holes where it goes into the subarachnoid space in the spinal cord
56
How and Where is the CSF absorbed
By the arachnoid villi into sagittal sinus
57
What is it called when arachnoid villi join together
Granulation Arachnoid