Cell Physiology Flashcards

1
Q

What makes up the plasma membrane

A

lipid bilayer + proteins

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2
Q

Basic framework of the plasma membrane

A

phospholipid bilayer

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3
Q

Components of the bilayer

A

hydrophilic heads and hydrophobic tails

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4
Q

hydrophobic tails are

A

nonpolar

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5
Q

form pores so that specific ions can flow across membrane; direction is determined by gradient

A

Ion channel

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6
Q

selectively move substances across membrane by undergoing a change in shape; good for larger molecules

A

Carrier/transporter protein

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7
Q

recognizes specific ligand and alters cell function; cellular recognition sites

A

receptors

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8
Q

catalyze chemical reactions in and outside of cell

A

enzymes

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9
Q

anchor proteins in the plasma membrane of neighboring cells to one another or to protein filaments.

A

linkers

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10
Q

Most permeant ion

A

K+

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11
Q

Lipid bilayer is selectively permeable to

A

nonpolar, small, and uncharged molecules

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12
Q

Nonpolar, small, and uncharged molecules can pass through membrane via

A

simple diffusion

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13
Q

small, uncharged polar molecules enter membrane via

A

channel

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14
Q

small, uncharged polar molecules enter membrane going

A

along gradient, no ATP

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15
Q

Not permeable to ions or large, uncharged polar molecules need a

A

transporter or channel and ATP

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16
Q

More hydrophobic (nonpolar)=

A

greater permeability

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17
Q

Degree of water permeability is influenced by

A

cholesterol content of bilayer

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18
Q

NaOH diffuses __ in higher concentrations

A

faster

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19
Q

Bigger the gradient= __ diffusion rate

A

faster

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20
Q

What makes up the Extracellular fluid

A

Interstitial fluid + plasma

21
Q

3 most prevalent ions in the ECF=

A

Na, Cl, HCO-3 (bicarbonate)

22
Q

3 most prevalent ions in the ICF=

A

K, HPO2-, and Mg2+

23
Q

what is 10 times more prevalent in the plasma than in the interstitial fluid

A

protein anions

24
Q

To find the amount of an ion in a concentration gradient….

25
What ions move from inside to outside
K+, Anions
26
What ions move from outside to inside
Na+, Ca2+, Cl-
27
Ions flow from a __ concentration to area of __ concentration
higher, lower
28
What makes up the electrochemical gradient
concentration gradient + electrical gradient
29
changes in membrane potential, charge separations across the membrane
Electrical gradient
30
At rest, the inside of the plasma membrane is
slightly negative
31
K+ ions are attracted to the
inside of the cell
32
the K+ electrical gradient is
inward, ECF to ICF
33
the difference in ion concentrations across the membrane
Chemical gradient
34
determine the direction and rate of ion movement through ion channels because ions are charged
Both electrical and chemical gradients
35
transmembrane proteins, water filled pores, can be open or closed
ion channels
36
Electrical signals in neurons are the result of
movement of ions across the membrane through channels
37
What molecules aren't affected by the electrical gradient
Uncharged molecules like O2 and H2O
38
Simple diffusion and channel-mediated diffusion of water have movement...
down concentration gradient
39
Channel mediated movement of ions have movement...
down electrochemical gradient
40
Facilitated diffusion (ion channels) require
ATP and membrane proteins
41
Cell maintains the concentration gradients through the transport protein
Na+/K+ ATPase
42
Na+/K+ ATPase is a
primary active transporter (pump)
43
Na+/K+ ATPase is active because.... and primary because....
moves ions against a concentration gradient using ATP, does the transporting and hydrolyzes ATP
44
The Na+/K+ ATPase uses the energy from...
hydrolyzing ATP
45
Na+/K+ ATPase pumps what in and out of the cell
pumps K+ ions into cell and Na+ out of cell
46
In the Na+/K+ ATPase pump, __ Na+ ions move
3, out of the cell (ICF to ECF)
47
In the Na+/K+ ATPase pump, __ K+ ions move
2 inside the cell (ECF to ICF)
48
More __ will move inwards to the cell down its electrical gradient
K+
49
Lipid molecules enter cell via
Simple diffusion