Cell Membrane 2 Flashcards
What do Glycoproteins and Glycolipids do?
They form a protective coat (glycocalyx) and form cell to cell recognition/ interaction
How much water is in the body of a 70kg man?
60% of the body is water, 42 of 70kg is water
What is Adipose tissue made of
90% lipids, majority are triglycerides
Small fraction of water
Females have slightly more
What is Skeletal Muscle made of?
75% water, 18% protein
Definition of osmosis
The movement of water across a membrane in response to a solute concentration gradient
-water moves from a region of low solute to high solute
What are aquaporin channels?
channels of transmembrane proteins that have a hole always open to allow water to pass through
Leak channels
2 Types of extracellular fluid
Interstitial fluid
Plasma
Ions High in Extracellular Fluid
Na+
Cl-
Ca2+
HCO3-
Ions Higher in Extracellular fluid
K+
Anions (HPO4-, H2PO4-)
Proteins
What is Osmotic Pressure
Pressure that would have to be applied to oppose and prevent osmosis
What is osmolarity?
The overall solute concentration of a compartment
-takes into account both penetrating and non-penetrating solutes
What is the normal osmolarity levels of the human body?
280-296 mOsM (around 300 mOsM)
Isosmotic
2 solutions have identical osmolarities (equal)
Hyperosmotic
Describes the solution with the higher osmolarity (greater than)
Hypoosmotic
Describes the solution with the lower osmolarity (less than)
Differences between Osmolarity from tonicity
Osmolarity: describes overall solute concentration
-takes into account all solutes, both penetrating and non penetrating
-measured in mOsM/L
Differences from Tonicity from osmolarity
-describes a solution relative to a cell based on how cell volume responds
-only focuses on non-penetrating solutes
-has no units, just comparative
-always compares a solution to a cell
-tells what happens when a cell is placed in a solution
Tonicity
Describes a solution and how it would affect cell volume if a cell were placed into the solution and allowed to come to equilibrium
Osmolality
Osmoles per kg of solvent