Cell Membrane 1 Flashcards
Biological rhythms and changes in set point
Variables are regulated within a normal range around a set point, but set points vary
Variables that change predictably and create repeating patterns or cycles of changes:
Biorhythms
What separates one compartment of a cell from another
Membranes: bilateral of phospholipids with protein molecules inside (lipid bilayer)
Functions of a cell membrane: Physical Isolation
-physical barrier seperating intracellular fluid and extra cellular fluid
-separates cell from environment
Functions of a cell membrane: Regulation of exchange with environment:
-controls entry, elimination, and release
(Selectively permeable)
Functions of a cell membrane: Communication
-between cell and its environment
-contains proteins that allow for responding or interacting with external environment
Functions of a cell membrane: Structural Support
-proteins in membrane are used to make cell-to-cell connections (tissue) and anchor to cytoskeleton
Average Composition of a cell membrane:
55% proteins
45% lipids
Small amount of carbohydrates
-not all cell membranes are created equally
Three Types of lipids found in the cell membrane:
Phospholipid: major lipid: main: 50-60%
Sphingolipids: lipid rafts: 30%
Cholesterol: increases viscosity and decreases permeability: 10-20%
T or F: All homeostatic set points for variables in the body remain constant
False
What is the Fluid Mosaic Model?
Current cell membrane model
-proteins dispersed throughout
-extracellular surface contains glycoproteins and glycolipids
What can be loosely or tightly bound to membranes?
Cell Membrane Proteins
Types of integral proteins
: Transmembrane and Lipid Anchored proteins
Roles of Integral Proteins
Membrane receptors
Cell adhesion molecules
Transmembrane movement (channels, carriers, pores, pumps)
Enzymes
Mediators of intracellular signalling
What do Peripheral Proteins do
Attach to integral proteins and are loosely attached to phospholipid head
Participate in intracellular signalling
Form submembraneous cytoskeleton