Cell division and cell determination Flashcards
1
Q
Which is the terminal executioner caspase that commits a mammalian cell to die?
A
Caspase 3, it is the exectutioner caspase which controls progression to DNA fragmentation, lodd of mitochondrial integrity and cellular fragmentation.
2
Q
What is caspase 9?
A
Caspase 9 is the initiator caspase of the intrinsic apoptotic pathway.
3
Q
What is caspase 8?
A
Caspase 8 is the initiator caspase of the extrinsic apoptotic pathway.
4
Q
What is caspase 2?
A
Caspase 2 is a lesser known initiator caspase that does not directly activate executioner caspases
5
Q
what is apoptosis?
A
Apoptosis is a form of programmed cell death regulated by multiple pathways.
