Cell Differentiation Flashcards
Cell Differentiation
Cells produced from zygote (not specialised) differentiating from eachother due to gene expression
Is DNA in all somatic cells the same regardless of cell function
Yes. Different gene expression is what enables cells to have different functions
2 Types of Stem Cell Division
Self-renewal and Differentiation
Self Renewal
Forms a daughter cell identical to stem cell to maintain stem cell number in body
Differentiation
Produces specialised cell to replace dead or damage cell
Niche
Microenviormnet around stem cells that supports signals to regulate self renewal and differntiation
3 Types of Niche
Direct, Soluble Factors and Intermediate Cell
Where stem cells are found
Embryonic - Blastocyte (fetus), Tissue (throughout Life) and Induced Pluipotent stem cells (lab)
Multipotent Def.
Can make many (but not all) types of specialised cells. Typically give rise to cells in tissue they belong to
Pluripotent Def.
Can make all types of specialised cells except extraembryonic
Totipotent Def.
Can make all types of specialised cells incuding extraembryonic
Embryonic Stem CElls location
Inner mass of blastocyte
What type of stem cell are embryonic srem cells
Pluripotent
Examples of Tissue Location
Skin, Brain, bone marrow and intestines
Committed Progenitors DEf.
Non self replicating. Multipotent. TRansiet Amplifying cells
