Caspi et al ERQ Flashcards

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1
Q

What can this study be used for?

A

Gene (molecular) 🧬

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2
Q

Year

A

Caspi et al (2003)

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3
Q

Aim

A

Test the role of 5-HTT gene in developing depression in response to stressful events

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4
Q

Participants

A

1037 children from New Zealand

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5
Q

Experimental design

A

A longtitudinal study (natural experiment)

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6
Q

Procedure

A
  • Genetic mapping was used to divide participants into three groups: 2 short alleles of 5-HTT, one short and one long allele, both long alleles
  • Participants were asses longtitudinally between ages 3 and 26.
  • A ‘life history calendar’ and an interview were used to asses stressful events and depressive symptoms
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7
Q

Results

A
  • Participants with 2 short alelles of 5-HTT gene reacted to stressful events with more depressive symptoms
  • This wasn’t true for participants who had two long alleles
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8
Q

Link to gene effects on behavior

A
  • Suggests that there may be genetical predisposition to depression
  • Genes may affect our reactions which in turn make us more susceptible to developing a mental condition
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9
Q

Evaluation

A

+ Big sample
+

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