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histology > cartilage > Flashcards

cartilage Flashcards

1
Q

it is distinguished by a high degree of compressive elasticity

A

cartilage

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2
Q

partially deformable, has shock absorbing properties and yet is firm in consistency

A

cartilage

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3
Q

the primary supportive tissue in fhe developing embryo and forms the structural framework from which most of the skeleton develops

A

cartilage

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4
Q

what provides the cartilage with its structural integrity

A

the arcade like arrangement of collagen fibers with the abundance of glycosaminoglycans

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5
Q

if cartilage is avascular, where does it get its nutritional supply

A

diffusion from the surrounding connective tissue, fluid from synovial joint, and medullary vessels of underlying bone

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6
Q

inportance of slippery characteristics of cartilage

A

reduces friction

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7
Q

the reason for the cartilage to have regenerative capacity

A

avascular nature

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8
Q

the formation of cartilage

A

chondrogenesis

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9
Q

mesenchymal cells will differentiate into

A

chondroblast

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10
Q

the primary support of the tissue

A

cartilage

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11
Q

the youngest cells, actually undifferentiated mesenchymal cells fsted to become chondroblast

A

chondrogenic cell

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12
Q

small stellate or spindle shaped cells located in the inner chondrogenic or cellular layer of perichondrium

A

chondrogenic cells

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13
Q

secretory cells that synthesize and secrete cartilage matrix

A

chondroblast

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14
Q

derived from chondrogenic cells and larger than the latter with round centrally round nuclei

A

chondroblast

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15
Q

they are not contained in the lacuna and located at the periphery of cartilage beneath the inner chindrogenic layer of preichondrium.

A

chondroblast

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16
Q

responsible for synthesis and maintenance of the extracellular matrix

A

chondroblast

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17
Q

it combines to form collagen fibers

A

pro-collagen chains

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18
Q

derived from chondroblast cell line

A

chondrocytes

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19
Q

these cells have been isolated and trapped in spaces called lacunae

A

chondrocytes

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20
Q

appears like swollen chondroblast embedded in large, ovoid or angular lacunae

A

chondrocytes

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21
Q

cells of cartilage

A

chondrocytes

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22
Q

have a reduced capacity for synthesis and secretion of cartilage matrix

A

chondrocytes

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23
Q

chondrocytes often occurs in groups called

A

isogenous or cell nests

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24
Q

spherical cells with fewer organelles than the chondroblast

A

chondrocytes

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25
Q

cells directly derived from chondrogenic cells.

A

chondroclats

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26
Q

also called cartilage eaters because they phagocytize cartilage matrix

A

chondroclast

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27
Q

they are responsible for shaping cartilage by removing or eating excess cartilage matrix

A

chondroclast

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28
Q

Cartilage is classified based on the

A

predominate type of fiber in the matrix

29
Q

this type of cartilage has matrix has fine, type II collagen fibers in the matrix.

A

hyaline cartilage

30
Q

These fibers are of similar refractive index to the surrounding ground substance and are not distinctly visible in the amorphous matrix.

A

hyaline cartilage

31
Q

The staining differences in the matrix of hyaline cartilage are due to

A

variations in proteoglycan content

32
Q

provides shape retention and tensile strength

A

fibers

33
Q

what type of collagen is present in the fibers of cartilage

A

type 2

34
Q

these component of the cartilage is responsible for the absorption of compression forces

A

amorphous gel-like matrix

35
Q

the amorphous gel-like matrix is composed of proteoglycans which serves as ______

A

the proteinaceous backbone to which the CHO in the form of GAGs are attached

36
Q

prinicipal GAGs in amorphous gel-like matrix

A

chondroitin sulfate and keratan sulfate

37
Q

a gelatinous mucopolysaccharide that binds the proteoglycans together into large aggregates

A

hyaluronic acid

38
Q

this type of cartilage is flexible and resilienrt

A

hyaline cartilage

39
Q

what type of cartilage is where the chondrocytes appear spherical, has lacuna, and collagen is the only fiber

A

hyaline cartilage

40
Q

a type of cartilage that is highly bendable and the matrix

A

elastic

41
Q

They serve as mechanical support and covers articulating surfaces of bones. They are model for formation of tubular bones and plays a role in repair of fractures.

A

hyaline cartilage

42
Q

term “hyalos” means

A

glassy as it appears white and glassy grossly

43
Q

Hyaline cartilage is found in the

A

tracheal rings and articular cartilage as well as the respiratory organs

44
Q

color of elastic cartilage

A

grossly yellow due to the yellow color of elastic fibers in the fresh state.

45
Q

Elastic fibers are distinctly visible as

A

short fine black (with silver stain) steaks in the amorphous matrix; while the collagen fibers are not visible.

46
Q

give the cartilage the ability to be deformed and return to shape

A

elastic fibers

47
Q

the matrix of elastic cartilage is mainly comprised of

A

elastic fibers and type 2 collagen

48
Q

Lacunae and cell nests are more frequent and closer together than in hyaline cartilage. Chondrocytes are bigger than those of hyaline cartilage and perichondrium is also present.

A

elastic cartilage

49
Q

where is elastic cartilage foubd

A

in the organs or structures that need resilience such as the pinna of the ear, eustachian tube, external auditory meatus, larynx and epiglottis

50
Q

has prominent, type I collagen fibers which are arranged in either an interwoven, herringbone pattern or a unidirectional fashion.

A

fibrocartilage

51
Q

Has a feature of both the DWFCT and cartilage, thus considered an intermediate between these two tissues.

A

fibrocartilage

52
Q

Composed of large bundles of collagen fibers separated by isolated groups of cartilage

A

fibrocartilage

53
Q

type of cartilage where the Chondrocytes tend to be arranged in somewhat regular rows rather than the obvious isogenous groups

A

fibrocartilage

54
Q

They are known to resist compression and tension

A

fibrocartilage

55
Q

where is fibrocartilage located

A

Located at transition points between DWFCT and cartilage or between DWFCT and bone, such as the pubic symphysis, periphery of the intervertebral disc where it forms a fibrous ring called annulus fibrosus, and the attachments of certain tendons and ligaments and in menisci.

56
Q

Maintenance and Repair of Cartilage

A

Cartilage is maintained throughout life by the nutritive role of chondrocytes.

57
Q

the type of hyaline cartilage that is acidophilic matrix due to lesser amoutn of glycosaminoglycans

A

young cartilage

58
Q

the reason why mature hyaline cartilage is basophilic

A

due to the accumulation of glycosaminoglycans

59
Q

these cartilage has flattened lacunae and chondrocytes

A

young carrilage

60
Q

this cartilage is large and ovoid lucana and chondrocytes, with cell nests and isogenous groups

A

mature

61
Q

what do you call the fibrous ring formws in the periphery of the intervertebral disc

A

annulus fibrosus

62
Q

principal component of the cartilage

A

intercellular substance

63
Q

cartilage is made up of

A

capsule, cells, intercerllular

64
Q

formed early by condensation from mesenchyml connective tissue. It is absent in the articular cartilage of the synovial joint

A

perichondrium

65
Q

made up of stellate or spindle-shaped chondrogenic cells from the fibroblast cell line.

A

intercellular or chondrogenic layer

66
Q

form the fiber network of cartilage matrix

A

collagen

67
Q

Cartilage matrix between lacunae are termed

A

inter-territorial matrix

68
Q

the territorial matrix is located

A

around the lacunar margin

histology (11 decks)

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