Cardiovascular System - Blood Flashcards
Exam 1
Cardiac Output
amount of blood dispelled from each ventricle in 1 minute; stroke volume x heart beat
Stroke Volume
quantity of blood ejected from one heartbeat
Heart Beat
number of beats per minute
Blood
only fluid tissue in body, composed of plasma and formed elements
Connective Tissue of Blood
type of tissue with nonliving fluid matrix called plasma and living blood cells called formed elements
Plasma
nonliving fluid matrix in blood, composed of over 90% water and containing dissolved solutes
Formed Elements
erythrocytes
leukocytes
thrombocytes
Why is blood red?
because of red blood cells, which contain hemoglobin
Hemoglobin
composed of a protein called heme, which binds oxygen and is responsible for the delivery of oxygen to the tissues
Erythrocytes
What percentage of total blood?
Red blood cells responsible for oxygen transport, comprising about 45% of whole blood
Leukocytes
White blood cells involved in immune response, found in small quantities in whole blood
Platelets
Cell fragments essential for blood clotting, present in the Buffy coat of whole blood
Hematocrit
Percentage of blood volume occupied by erythrocytes, with normal values of 42-47% for males and 37-42% for females
Buffy Coat
Thin, whitish layer in a spun tube of blood, containing white blood cells and platelets
Plasma Proteins
List Examples
Abundant solutes in blood plasma, including albumin, globulin and fibrinogen proteins
Average Blood Volume Levels
Males: 5 - 6L
Females: 4 - 5L
Hempatopoiesis
production and development of blood
Where does Hematopoiesis take place? (Fetus, Infants, Adults)
fetus: placenta, liver
infants: red bone marrow (of spongy bone), liver
adults: red bone marrow (of spongy bone)
Where is most blood found?
hip bone (flat bone)
Functions of Blood
transport: respiratory gases, nutrients, hormones, electrolytes (ions)
protect: fight infection, prevent hemorrhaging
regulation: maintain pH, fluid volume, body temp
What is the benefit of the shape of RBCs?
biconcave shape; offers huge surface area to transport gas
Study Tree Chart of Blood
GO STUDY IT
How do WBCs fight infection?
phagocytosis; emigrate (diapedesis) blood vessel and extracellular matrix
Phagocytosis
when a cell eats/engulfs another cell
When monocytes emigrate, what happens?
They either fuse together, becoming macrophages OR remain monocytes and FIGHT
How can edema occur?
plasma (fluid) emigrates into extracellular matrix, increasing the amount of extracellular fluid, causing swelling
What is inflammation?
swelling of individual cells
Do WBC have phospholipid bilayer?
No, instead they have pseudopodium
How does phagocytosis occur?
enzymes of ribosomes, inside lysosomes, digest other cells
Lysosome
organelle responsible for intracellular digestion (AKA cell receptionist)
What are the components of the endomembrane system?
Rough ER; Golgi Apparatus; Lysosome
Chemotaxis
chemical attraction of leukocytes to tissue damage/infection
List the Granular Leukocytes
Neutrophils; Basophils; Eosinophils
List the Agranular Leukocytes?
Lymphocytes; Monocytes
Neutrophils
most numerous WBCs; mononucleic; have multiple nuclear lobes b/c cytokinesis did not follow mitosis; phagocytic
Eosinophils
WBCs involved in allergies, asthma, and defense against parasites