Cardiovascular System Flashcards
Function of the system
What does it include
- pumps blood and contents to all cells for metabolite exchange and immune response
- cardiovascular and lymphatic
List the components of the cardiovascular system and what they do generally
1 heart - has 4 chambers to receive blood and pump blood
2 arteries - efferent to the blood. Transports blood away from heart
3 capillaries- responsible for metabolite exchange between tissue and blood
4 veins - afferent to blood and carries blood back to heart for pumping
List and describe the 2 major systems of the cardiovascular system
List the basic blood flow pattern
1 pulmonary - pumps deoxygenated blood to lungs for oxygenation
2 systematic- pumps oxygenated blood to the body
-right atrium / right ventricle / lungs / left atrium / left ventricle / body
What is internal surface of blood and lymph system lined with
And it’s function the lining
/simple squamous epithelium called endothelium
1 semi permeable for metabolite exchange
2 controls where exudate enters CT
3 antithryombogenic barrier
4 secret of factors for growth of other cells
Function of the heart and properties
What supplies heart with nutrients
- rhythmic contractions to pump blood into the cardiovascular vessels
- has 4 chambers
- is auto-rhythmic
-coronary arteries
List the 3 layers of the heart muscle
1 endocardium
2 myocardium
3 epicardium
Describe the endocardium structure , function
- thin inner layer of endothelium with CT.
- middle layer of smooth muscle called myoelastic
- subendocardial outer layer of CT which merges with myocardial layer
- subendocardial layer has modified cardiac fibers part of hearts impulse conducting system
Describe myocardial layer structure and function
- thickest middle layer of heart muscle
- around each chamber spirally
Why are ventricle myocardial thicker than atria ones
-a lot of force is required to pump blood as compared to receiving it
Describe epicardium structure and function
- outer layer of endothelium and CT with blood vessels and nerves for the Heart
- continuous with outer covering of heart called Pericardium
- it’s adipose cushions underlying structures during movement
- fluid of pericardial mesothelium prevent friction
List all parts of the heart
- atrium
- ventricle
- sinoatrial node
- internodal pathways
- atrioventricular node
- valve cusps
- papillary muscle
- atrioventricular bundle ( Bundle of His )
- interventricular septum
- purikinje fibers
- chordae tendinae
- valve flaps
Describe heart valves
How anchored In heart
Function of chordae tendinae
- flaps of CT anchored in the CT of the heart
- has chordae tendinae that extend from cusp to papillary muscle
-prevent valve from turning inside out during ventricle contraction
Describe impulse structures from AV node to apex of heart
- AV continuous with His bundle which gives rise to right and left bundles that run in interventricular septum
- run to apex of heart and divide into purkinje fibers
Describe structure and function of cardiac skeleton
-dense fibrous irregular CT which 1 makes interventricular septum
2 surrounds all valves and extend to valve cusp and chordae tendinae
3 provide insertion joint for cardiac muscle
4 provide electrical insulation between atria and ventricle
Describe structure, location and function of impulse system from SA nodes to purkinje fibers
—SA node is modified muscle fibers. Impulse initiated here and move along myocardial of both atria along internodal pathway
- stimuli reaches AV node and this propagates along His bundle to purkinje bundle
- purkinje have fewer myofibrills and much glycogen and stimulate both atrium and ventricles
What innervates the heart and it’s effects
Where are their ganglia found
- parasympathetic ( slows down )and sympathetic ( speeds up )system
- near SA and AV nodes
How does angina pectoris come about
-free afferent fibers between myocardium fibers register pain
What do walls of vasculature have
What determines the amount and arrangement
- endothelial and smooth muscle in veins and arteries
- only endothelial in capillaries
-mechanical and metabolic factors
Endothelial function
- semi permeable barrier facilitating exchange of metabolites between tissue and blood
- control where exudate is released ( immune roles )
- secrete factors which influence growth of other cells
- modulate blood flow by release of factors such as endothelin 1 , prostacyclin
Why doesn’t endothelial clot
-due to release of anticoagulants such as heparin
What does VEGF do and how does it do it
- vascular endothelial growth factors stimulate vascular formation from mesoderm ( vasculogenensis )
- Maintain adult capillaries
- stimulate sprouting of already existing capillaries ( angiogenesis )
-endothelial recruits smooth muscle and fibroblasts to form vascular tissue
Where is smooth muscle present and it’s structure
Why do arteries have gap junctions
- in vessels larger than capillaries
- to modulate blood flow via vasoconstriction and vasodilation
Where elastic fibers present, why and in what structure
- in arteries to allow the vessels to expand under pressure
- as lamellae
What is tunics and. And them
-concentric layers of CT of vessels
1 initima
2 media
3 adventitia